Article
Oncology
Nilay Aksoy, Emine Sen, Susi Sukmasari, Ozlem Bingol Ozakpinar, Feyze Aricioglu, Yasemin Yucel Yucel, Muhammet Ridvan Dumlu, Abd Almonem Doolaanea, Mohammad Nasrin AbdulRahman, Vakur Olgac, Piril Bozkan, Bugra Ozan
Summary: This study evaluated the preventive effect of Eugenia jambolana extract against 5-FU-induced mucositis. The results showed that a 3% gel of Eugenia jambolana had a significant preventive effect, making it a viable option for preventive strategies.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2022)
Article
Plant Sciences
Ellen Nayara Silva de Jesus, Mateus Silva Tavares, Pedro Anibal C. Barros, Daniele Carvalho Miller, Pedro Iuri C. da Silva, Jofre Jacob S. Freitas, Anderson B. de Lima, William N. Setzer, Joyce Kelly R. da Silva, Pablo Luis B. Figueiredo
Summary: This study evaluated the acute oral toxic, antinociceptive, and anti-inflammatory activities of Eugenia uniflora essential oil. The essential oil showed analgesic and anti-inflammatory effects without causing toxicity in animals.
JOURNAL OF ETHNOPHARMACOLOGY
(2023)
Article
Plant Sciences
Ju-Hsin Cheng, Ho-Cheng Wu, Chia-Hung Yen, Tsong-Long Hwang, Horng-Huey Ko, Hsun-Shuo Chang
Summary: Non-alcoholic fatty liver disease (NAFLD) is a liver disease caused by the accumulation of excess lipids. The research aimed to investigate the bioactive components of Formosan plants that could reduce lipid droplet accumulation. The study found that the methanolic extract of Elaeagnus glabra Thunb. showed excellent anti-LD accumulation activity and isolated several compounds with potential therapeutic effects.
Article
Biochemistry & Molecular Biology
Oberdan Oliveira Ferreira, Silvia Helena Marques da Silva, Mozaniel Santana de Oliveira, Eloisa Helena de Aguiar Andrade
Summary: The chemical compositions of essential oils from Myrcia multiflora and Eugenia florida were analyzed using gas chromatography and flame ionization detection, and their fungicidal potential against five yeast fungicide species was evaluated. Myrcia multiflora (B) essential oil showed significant inhibitory effect against the fungal species.
Review
Chemistry, Organic
Tran Trung Hieu, Nguyen Thi Chung, Vo Cong Dung, Dau Xuan Duc
Summary: Melia azedarach, a member of the mahogany family, has been traditionally used in folk medicine and recent studies have revealed its diverse range of bioactivities and isolated organic compounds, suggesting its potential therapeutic value.
CURRENT ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Applied
Saulo Almeida de Menezes, Giulia Bongiorni Galego, Graziela de Vargas Rigo, Julio Cesar Ribeiro de Oliveira Farias de Aguiar, Bruno de Oliveira Veras, Lilian Cortez Sombra Vandesmet, Cicero Ramon Bezerra dos Santos, Mariana Gomes Vidal Sampaio, Clecia de Carvalho Marques, Vilmar Luiz Lermen, Daniela Maria do Amaral Ferraz Navarro, Marcia Vanusa da Silva, Maria Tereza dos Santos Correia, Tiana Tasca
Summary: The study reveals the anti-Trichomonas vaginalis activity of essential oils from Myrtaceae in Caatinga. These oils exhibit varied efficacy against T. vaginalis isolates, with Eugenia pohliana essential oil showing promising selectivity towards vaginal epithelial cells. The combination of this essential oil with metronidazole shows a synergistic effect, indicating different mechanisms of action.
NATURAL PRODUCT RESEARCH
(2023)
Article
Chemistry, Applied
Mariana Gomes Vidal Sampaio, Cicero Ramon Bezerra Dos Santos, Lilian Cortez Sombra Vandesmet, Bruno Souza Dos Santos, Izabelly Bianca Da Silva Santos, Maria Tereza dos Santos Correia, Arthur Lima de Berredo Martins, Luis Claudio Nascimento da Silva, Irwin Rose De Alencar Menezes, Maria Celeste Veja Gomez, Marcia Vanusa Da Silva
Summary: The study evaluated the volatile composition, antioxidant, and antiprotozoal activities of the essential oil obtained from leaves of Eugenia gracillima Kiaersk in the Brazilian Northeast area. The oil showed weak to moderate antioxidant activity and high selectivity against Leishmania parasites, suggesting it as a potential source for anti-Leishmania drug development.
NATURAL PRODUCT RESEARCH
(2021)
Article
Chemistry, Applied
Vu Huong Giang, Le Thi Thuy, Pham Thi Cham, Le Ba Vinh, Ninh Khac Ban, Tran My Linh, Nguyen Chi Mai, Pham Thi Hoe, Tran Thu Huong, Nguyen Hai Dang, Hyuncheol Oh, Tran Hong Quang
Summary: Phytochemical investigation of Lycopodiella cernua whole plants led to the isolation and identification of three new compounds and 12 known ones. Some of the compounds displayed inhibitory effects on NO in BV2 cells and cytotoxic activity against various cancer cell lines.
NATURAL PRODUCT RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Wenjie Yu, Fengjie Sun, Ruixin Xu, Meng Cui, Yongquan Liu, Quanyuan Xie, Limin Guo, Chenxian Kong, Xin Li, Xiali Guo, Liping Luo
Summary: This study comprehensively investigated the physicochemical parameters, chemical composition, and antioxidant capacity of Castanopsis honey (CH), as well as evaluated its anti-inflammatory effects. The results showed that CH has high quality and contains various compounds and phenols, which exhibit significant antioxidant and anti-inflammatory activities.
Article
Biochemistry & Molecular Biology
Oberdan Oliveira Ferreira, Celeste de Jesus Pereira Franco, Everton Luiz Pompeu Varela, Sebastiao Gomes Silva, Marcia Moraes Cascaes, Sandro Percario, Mozaniel Santana de Oliveira, Eloisa Helena de Aguiar Andrade
Summary: This study investigated two specimens of Eugenia florida from different areas in Brazil, analyzing the chemical composition and antioxidant activity of the essential oils extracted from these specimens. The results showed variations in chemical composition and antioxidant activity between the samples, indicating potential differences in the medicinal properties of E. florida from different regions.
Article
Chemistry, Applied
Cicero R. B. dos Santos, Mariana G. V. Sampaio, Lilian C. S. Vandesmet, Bruno S. dos Santos, Saulo A. de Menezes, Benedito Y. M. Portela, Douglas W. R. Gomes, Maria T. S. Correia, Maria C. V. Gomez, Irwin de Alencar R. Menezes, Marcia V. da Silva
Summary: This study investigated the volatile components and activities of the essential oil obtained from the leaves of Eugenia stipitata McVaugh. The oil showed high selective activity against Leishmania braziliensis and good antibacterial activity. However, its free-radical scavenging activity was low. These findings suggest that the essential oil of Eugenia stipitata is a valuable source for the development of antibacterial and antiprotozoal drugs.
NATURAL PRODUCT RESEARCH
(2023)
Article
Agricultural Engineering
Dan Bahadur Pal, Neha Srivastava, Sunder Lal Pal, Mohit Kumar, Asad Syed, Abdallah M. Elgorban, Rajeev Singh, Vijai Kumar Gupta
Summary: This study investigated the pyrolysis of mangifera indica L., Artocarpus heterophyllus L., and jambolana seeds, revealing their rich lignocellulosic composition and varying apparent activation energies during pyrolysis at different conversion rates.
BIORESOURCE TECHNOLOGY
(2021)
Article
Materials Science, Paper & Wood
Hanoch Julianus Sohilait, Healthy Kainama, Martha Kaihena
Summary: The essential oils of clove species Eugenia caryophyllata (COs) from northern Buru Island were analyzed and found to contain high levels of eugenol, beta-caryophyllene, and eugenyl acetate. COsI of bud exhibited superior antioxidant activity.
Article
Biochemistry & Molecular Biology
Tiss Mohamed, Zoubeida Souiy, Lotfi Achour, Khaled Hamden
Summary: This study found that extracts of Globularia alypum exhibited anti-obesity, anti-hyperglycaemic, antipyretic, and analgesic activities.
ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Luciola Bagatini, Giovana Paula Zandona, Jessica Fernanda Hoffmann, Juliane de Souza Cardoso, Fernanda Cardoso Teixeira, Liziane Schittler Moroni, Alexander Junges, Aniela Pinto Kempka, Francieli Moro Stefanello, Cesar Valmor Rombaldi
Summary: Pitangueira leaves were extracted using aqueous infusion (AI) and pressurized liquid extraction (PLE). LC-MS identified 54 compounds in the extracts. PLE-W:E extract had higher concentrations of phenolic acids and tannins, while PLE-E extract had higher concentrations of flavonoids. All extracts exhibited antioxidant, antibacterial, and allelopathic activities, with PLE extracts showing more regular activity.
SUSTAINABLE CHEMISTRY AND PHARMACY
(2023)
Review
Environmental Sciences
Zhiping Niu, Zhizhou Duan, Hongmei Yu, Lina Xue, Feifei Liu, Dong Yu, Keying Zhang, Donghui Han, Weihong Wen, Hao Xiang, Weijun Qin
Summary: Recent studies suggest that long-term exposure to particulate matter is associated with increased blood pressure and hypertension risk.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
(2023)
Article
Environmental Sciences
Su-chun Wang, Guang-zhou Liu, Fei-fei Liu
Summary: This study investigated the physiological and metabolic effects of polystyrene (PS) and aged polystyrene (A-PS) microplastics on Dunaliella salina. It was found that they inhibited the growth of microalgae but promoted pigment synthesis. Oxidative stress analysis showed that PS and A-PS caused oxidative damage to algal cells. Metabolomics analysis showed that PS and A-PS significantly increased different metabolites.
ENVIRONMENTAL POLLUTION
(2023)
Article
Oncology
Ronald Cheung, Emma Ito, Marianela Lopez, Ed Rubinstein, Harald Keller, Fred Cheung, Zhihui Amy Liu, Fei-Fei Liu, Philip Wong
Summary: This study assessed the environmental impact of shorter and more intense hypofractionated regimens and virtual care during the COVID-19 pandemic. The carbon footprint was reduced by 39% during the pandemic year, and there was no increased rate of acute radiation-related adverse events.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2023)
Article
Construction & Building Technology
Chenglong Shi, Jigang Zhang, Xiangying Wang, Feifei Liu, Wenli Chen, Zhehao Ma, Haizhi Liang, Yang Zhao
Summary: Pendulum impact testing and numerical analysis were conducted for the first time on civil air defense walls sprayed with 2-mm polyisocyanate-oxazodone (POZD) coatings at different positions, in order to prevent serious casualties and secondary injuries caused by high-speed splashing concrete fragments. The results showed that spraying a 2-mm POZD coating can significantly reduce damage, restrain splashing of fragments, ensure wall integrity, and improve impact resistance and airtightness. Additionally, using large-rupture-strain fiber-reinforced polymer (FRP) on the back improved bending stiffness and deformation capacity, reducing residual displacement. The failure modes and characteristics obtained from this study provide evaluation criteria for existing civil air defense walls.
JOURNAL OF STRUCTURAL ENGINEERING
(2023)
Review
Oncology
Ronald Chow, Julie Midroni, Jagdeep Kaur, Gabriel Boldt, Geoffrey Liu, Lawson Eng, Fei-Fei Liu, Benjamin Haibe-Kains, Michael Lock, Srinivas Raman
Summary: The aim of this study is to provide a comprehensive understanding of the current landscape of artificial intelligence (AI) for cancer clinical trial enrollment and its predictive accuracy. The study found that AI demonstrated comparable or superior performance to manual screening for patient enrollment in cancer clinical trials, with accuracy, sensitivity, and specificity exceeding 80% in most datasets. AI is highly efficient and requires less time and human resources for screening patients.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2023)
Article
Engineering, Marine
Qingfeng Yan, Jigang Zhang, Feifei Liu, Zhehao Ma, Guoliang Zhao, Chi Gu, Hanyu Song, Yang Zhao
Summary: This study investigates the performance of T-joints in the jacket foundation of offshore wind turbines under impact loading by means of experimental and simulation analysis. The deformation pattern and dynamic response of one hollow T-joint and eight concrete-filled double steel tubular T-joints (CFDST T-joints) are explored through a pendulum testing machine. The experimental results indicate that the local indentation dominates in the deformation process of hollow T-joint while the failure mode of CFDST T-joint will be commonly the global bending. The impact force-displacement curves corresponding to different parameters have similar tendencies and each curve can be divided into four stages. Increasing the impact velocity and axial compression ratio can reduce impact resistance. Meanwhile, increasing outer tube thickness and changing hollow rate exert a remarkable effect on the dynamic performance. Finite element models are then proposed to validate the experimental results and investigate the energy dissipation mechanism of T-joints under impact loading. The plastic deformation of the outer tube is the main energy dissipation mechanism for CFDST T-joints. In general, the investigation in this study offers a reliable basis for the study of impact failure mechanism for CFDST T-joint.
Article
Environmental Sciences
Feifei Liu, Xiangxiang Wang, Mengnan Pan, Ke Zhang, Feng Zhou, Jiahui Tong, Zhongyang Chen, Hao Xiang
Summary: This study found that sustained exposure to higher concentrations of air pollutants is associated with increased prevalence of metabolic syndrome (MetS) and its components. For every 10μg/m³ increase in air pollutant concentrations, the risk of MetS increased. The study also identified that age may significantly modify the association between air pollution and MetS.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Food Science & Technology
Kara J. Torrey, Yongqiang Liu, Huifang Li, Hang Ma, Christopher W. Via, Matthew J. Bertin, Navindra P. Seeram
Summary: Maple water products, tapped directly from maple trees, lack industry consensus on their authenticity, hindering their promotion in the functional beverage market. This study aims to establish standards of identity for maple water and analyze its chemical composition. The research shows that pasteurized maple water has a stable chemical composition over a 12-month period and exhibits similar phytochemical profiles and chemical characteristics to phenolic-enriched maple syrup extract. Additionally, both maple water and maple syrup extract show moderate antioxidant and anti-inflammatory effects. This critical information will help define and distinguish maple water from other beverages, promoting growth in the maple industry.
Article
Multidisciplinary Sciences
Shuhui Sun, Shuai Ma, Yusheng Cai, Si Wang, Jie Ren, Yuanhan Yang, Jiale Ping, Xuebao Wang, Yiyuan Zhang, Haoteng Yan, Wei Li, Concepcion Rodriguez Esteban, Yan Yu, Feifei Liu, Juan Carlos Izpisua Belmonte, Weiqi Zhang, Jing Qu, Guang-Hui Liu
Summary: This study investigates the phenotypic and molecular adaptations to exercise in young and old mice, and reveals that exercise protects tissues from infectious injury, suppresses inflammaging in aged individuals, and improves the central nervous system and systemic vasculature. The study also uncovers the role of the core circadian clock protein BMAL1 in delaying senescence and promoting recovery from infectious damage, resembling the beneficial effects of exercise. These findings highlight the significance of exercise in rejuvenating the circadian clock network and pave the way for further exploration of the interaction between exercise, aging, and immune challenges in the whole organism.
Article
Geochemistry & Geophysics
Yuan Sun, Feifei Liu, Jia Liu, Liangxi Chen, Yan Li, Hongrui Ding, Anhuai Lu
Summary: In this study, a simulated photoelectron system was used to investigate the effects of semiconducting mineral photoelectrons on the microbial community and sulfate reduction. The results showed that photoelectrons had significant impacts on microbial community diversity and sulfate reduction rate, and promoted the enrichment of sulfate-reducing bacteria. This process has important implications for carbon and sulfur element cycling as well as the formation of dolomite.
Article
Chemistry, Multidisciplinary
Na Xu, Keyi Di, Feifei Liu, Wencheng Zhao, Bo Zhang
Summary: This study proposes a risk assessment method for lift-jacking accidents, using a combination of fuzzy fault tree analysis (FFTA) and failure mode and effects analysis (FMEA). Qualitative analysis of the fault tree is used to identify risk factors, and a hybrid approach is applied to quantify the probability of each bottom event. The FFTA-FMEA model aggregates expert assessments to effectively eliminate ambiguity and uncertainty, and facilitates the quantification and identification of medium to high-risk factors in lift-jacking accidents.
APPLIED SCIENCES-BASEL
(2023)
Article
Engineering, Civil
Di Zhao, Jigang Zhang, Feifei Liu, Zhehao Ma, Guoliang Zhao, Chi Gu, Weicheng Zhang, Hanyu Song
Summary: The dynamic response to lateral impact of steel tube confined concrete with a circular hollow section was investigated through laboratory pendulum impact tests. The results showed that increasing the outer wall thickness and adopting an appropriate hollow ratio can effectively improve the impact resistance of such columns.
THIN-WALLED STRUCTURES
(2023)
Article
Public, Environmental & Occupational Health
Xiu Jin, Feifei Liu, Ya Zhang, Yingying Ma, Linqing Yang, Yunfei Wang, Ying Liu
Summary: This study aimed to investigate the infection status of HR-HPV E6/E7 mRNA in ASCUS patients and analyze the pathogenic rate of different HPV subtypes, providing a more accurate basis for managing ASCUS patients. It was found that colposcopy referral or further biopsy is recommended for ASCUS patients with HPV16/18/45E6/E7 mRNA positivity and postmenopausal patients with HR-HPVE6/E7 mRNA positivity.
Article
Radiology, Nuclear Medicine & Medical Imaging
Feifei Liu, Mingtong Liu, Meiting Li, Yuwei Xin, Dongping Gao, Jun Wu, Jiaan Zhu
Summary: This study successfully extracted relevant knowledge from Chinese electronic medical records using a small number of manually annotated samples and established a knowledge graph for rheumatoid arthritis using a combination of pretrained language models and deep neural networks.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Meeting Abstract
Oncology
Matthew Lunning, Kristen A. Deger, Fei Fei Liu, Ahmed Elsada, Sven L. Klijn, Michal Litkiewicz, Conrado Franco-Villalobos, Sonja V. Sorensen
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA
(2023)
