Article
Veterinary Sciences
Wenhao Li, Weike Zeng, Yanping Zhang, Zhijie Ma, Xingyan Fang, Yingcang Han, Yonggang Sun, Xiayang Jin, Liuyin Ma
Summary: This study investigates the metabolite composition of yak milk and its role in hypoxic stress tolerance, comparing it to human milk. The results show that yak milk relies on certain essential amino acids to tolerate hypoxic stress, while human milk utilizes neuroprotective effects of non-essential amino acids or derivates. Additionally, metabolites related to hypoxic stress are more abundant in yak colostrum compared to yak mature milk.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Chemistry, Analytical
Anna Zubrycka, Andrzej Kwasanica, Monika Haczkiewicz, Karolina Sipa, Konrad Rudnicki, Slawomira Skrzypek, Lukasz Poltorak
Summary: This study analyzed 5647 street samples and identified 53 illicit drugs, with Delta-9-tetrahydrocannabinol, amphetamine being the most common. Except for methadone, almost all samples were spiked with at least one cutting agent, with caffeine being the most frequently found adulterant.
Article
Chemistry, Multidisciplinary
Xiabin Chen, Xingyu Deng, Yun Zhang, Yanan Wu, Kang Yang, Qiang Li, Jiye Wang, Weixuan Yao, Junsen Tong, Tian Xie, Shurong Hou, Jianzhuang Yao
Summary: BZE, the major toxic metabolite of cocaine, was successfully degraded into inactive metabolites by a redesigned bacterial cocaine esterase. A new mutant, BZEease2, showed significantly improved catalytic efficiency in vivo, potentially useful for cocaine overdose treatment and environmental BZE clearance.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Analytical
Jonas Carneiro Cruz, Mariana Azevedo Rosa, Lucas Mores, Eduardo Carasek, Jose Alexandre de Souza Crippa, Eduardo Costa Figueiredo, Maria Eugenia Costa Queiroz
Summary: This manuscript describes the development of magnetic restricted-access carbon nanotubes as a sorbent for determining CBD and THC in human plasma samples. The method showed adequate selectivity, linearity, precision, and accuracy. It was successfully applied to determine CBD levels in healthy volunteers and THC levels in cannabis smokers.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Josimar M. Batista, Maria J. Neves, Helvecio C. Menezes, Zenilda L. Cardeal
Summary: A new amino acid extraction method using functionalized magnetic carbon nanotubes was developed and optimized, which showed excellent extraction of analytes. Exposure of Saccharomyces cerevisiae to BaP at a concentration of 25.0 μmol L-1 caused changes in cell viability, indicating metabolic alterations. A fast and efficient GC/MS method was optimized to determine 16 amino acids in yeasts exposed or not to BaP. Comparison of amino acid concentrations revealed statistically significant differences in glycine, serine, phenylalanine, proline, asparagine, aspartic acid, glutamic acid, tyrosine, and leucine, suggesting their potential as toxicity biomarker candidates.
Article
Chemistry, Analytical
Xinqi Sun, Jiaoyang Luo, Qian Lu, Chunyu Li, Zhigao Zhao, Fang An, Meihua Yang
Summary: In this study, a new method using a combination of MWNTs-OH and other materials was developed for solid-phase extraction and detection of pesticide residues in Lonicerae japonicae flower buds. The method showed high purification efficiency and good recovery.
MICROCHEMICAL JOURNAL
(2022)
Article
Food Science & Technology
Sebastian Imperiale, Elke Kaneppele, Ksenia Morozova, Federico Fava, Demian Martini-Losch, Peter Robatscher, Giovanni Peratoner, Elena Venir, Daniela Eisenstecken, Matteo Scampicchio
Summary: Hay milk is a traditional dairy product protected as traditional specialty guaranteed (TSG), with strict regulations to ensure authenticity. The study proposes two analytical approaches using GC-MS and HPLC-HRMS to differentiate milk containing silage, successfully predicting the use of maize or grass silage in cow's diet with 100% recognition. The findings suggest that analytical approaches based on HRMS are a viable authentication method for hay milk.
Article
Food Science & Technology
Wei Ren, Mengqi Sun, Xiaoyuan Shi, Tianqi Wang, Yonghui Wang, Xinrui Wang, Bingjian Huang, Xiyan Kou, Huili Liang, Yinghui Chen, Changfa Wang, Mengmeng Li
Summary: This study demonstrates that the lipid and VOC profiles of donkey milk are influenced by dietary roughage, with corn straw group (G1 group) having the highest variety and content of triacylglycerol species, and the wheat group (G2 group) and wheat straw group (G3 group) showing significantly increased VOCs, with the greatest difference found between G1 and G2 groups.
Article
Biochemistry & Molecular Biology
Ema Almeida, Sofia Soares, Joana Goncalves, Tiago Rosado, Nicolas Fernandez, Jesus M. Rodilla, Luis A. Passarinha, Mario Barroso, Eugenia Gallardo
Summary: Drug abuse is a global problem with increased risks of diseases, injuries, and deaths. This study evaluates the long-term stability of cocaine and opiates in oral fluid samples and optimizes the conditions for improved stability.
Article
Medicine, Legal
Liz Arango-Merino, Caterin Quevedo-Castro, Julian Mancera-Barros, Alvaro Emilio Sarmiento-Gutierrez, Victoria A. Arana, Judith Granados-Reyes
Summary: This study conducted a descriptive statistical analysis of cutting agents found in 2118 seized cocaine samples in the Northern Region of Colombia from 2015 to 2017. The most commonly used cutting agents in these samples include caffeine, phenacetin, lidocaine, imidazole and levamisole. The cocaine samples showed different mixtures of cutting agents, with caffeine/phenacetin and caffeine/lidocaine/phenacetin being the predominant mixtures.
FORENSIC SCIENCE INTERNATIONAL
(2021)
Article
Environmental Sciences
Hanna Mojska, Iwona Gielecinska, Joanna Winiarek, Wlodzimierz Sawicki
Summary: The study found that the level of acrylamide in colostrum was significantly lower than in mature milk, and that breastfeeding women had significantly lower acrylamide intake from hospital diets compared to home diets. There was a positive correlation between dietary acrylamide intake by breastfeeding women and its content in breast milk.
Article
Biochemical Research Methods
Qingqing Li, Wenmin Zhang, Yuheng Guo, Hui Chen, Qingqing Ding, Lan Zhang
Summary: A material called oxygenated carbon nanotubes cages (OCNTCs) was prepared for the extraction of aromatic amines (AAs) in food contact materials. This material showed high selectivity for AAs and a sensitive analysis method was developed with low limits of detection and good precision.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Article
Chemistry, Applied
Shihuan Li, Senwei Feng, Ann Van Schepdael, Xu Wang
Summary: This study proposes a sensitive method for detecting the impact of bisphenols and triclosan, commonly found in various products, on human health. The results show that the method has low intra-day and inter-day variations, as well as good reproducibility and lifespan.
Article
Food Science & Technology
Taotao Dai, Xixiang Shuai, Jun Chen, Changhong Li, Jiali Wang, Wei Liu, Chengmei Liu, Risi Wang
Summary: Whole peanut milk (WPM) prepared using an industry-scale microfluidization system (ISMS) showed improved physical stability and changed properties under different pressures, including particle size, distribution, and flavor substances.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Engineering, Environmental
Debora Sorolla-Rosario, Julio Llorca-Porcel, Monica Perez-Martinez, Dolores Lozano-Castello, Agustin Bueno-Lopez
Summary: This study tested the application of carbon sorbents in Thermoextraction-Desorption Gas Chromatography-Mass Spectrometry (TED-GC-MS) technique and found that carbon sorbents have better retention performance compared to traditional PDMS sorbents. The carbon materials' advantages lie in their slit-type pores, which are ideal for retaining aromatic compounds released from most polymers, and their higher retention capacity compared to PDMS. The combination of PDMS+carbon sorbents can further improve the retention of the most representative compounds for each polymer, but the experimental procedure becomes more complicated. Additionally, carbon materials are effective in retaining chlorinated compounds released from PVC thermodecomposition, which PDMS sorbents cannot do.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2022)
Article
Microbiology
Andre Angelo Medeiros Gomes, Simone Albino Paes, Ana Paula Sato Ferreira, Danilo Batista Pinho, Zenilda de Lourdes Cardeal, Helvecio Costa Menezes, Patricia Gomes Cardoso, Olinto Liparini Pereira
Summary: This study aimed to discover the Induratia species producing volatile organic compounds (VOCs) in Carqueja plants used in traditional medicine and coffee plants in Brazil. Eleven fungal isolates producing volatile metabolites were obtained, with I. coffeana CCF 572 showing antimicrobial activity against multiple Aspergillus species.
BRAZILIAN JOURNAL OF MICROBIOLOGY
(2023)
Article
Environmental Sciences
Elson Silva Galvao, Henrique Bittencourt Paiva, Helvecio Costa Menezes, Taciana Toledo de Almeida Albuquerque, Zenilda de Lourdes Cardeal
Summary: A risk assessment and source apportionment of PAHs in a highly trafficked and industrialized region in southeastern Brazil revealed higher concentrations of PAHs during the summer due to fire outbreaks. The study identified four potential sources through isomer ratio diagnostic and PCA, which were confirmed and apportioned using the PMF model as gasoline-related (31.8%), diesel-related (25.1%), biomass burning (23.4%), and mixed sources (19.6%). The overall cancer risk was tolerable, with ingestion being the major exposure route. Mixed sources contributed the most to the cancer risk, followed by gasoline-related, diesel-related, and biomass burning sources. Higher risks were associated with PM2.5-bound PAHs exposure, highlighting the need for mitigation measures.
Review
Chemistry, Multidisciplinary
Samantha C. H. Rodrigues, Helvecio C. Menezes, Dawidson A. Gomes, Zenilda L. Cardeal
Summary: Metabolomics provides information about the biochemical and physiological state of a biological system. Gas chromatography coupled to mass spectrometry (GC-MS) is widely used for metabolomic analysis due to its advantages in sensitivity, resolution, reproducibility, database coverage, and cost. This review focuses on the sampling, sample preparation, data processing, and GC-MS analysis of metabolomic studies of damaged skin. It also discusses the biological interpretation of certain metabolites in photoexposed skin and melanoma. Lastly, the integration of skin metabolomics with other omics sciences for improved diagnosis is presented.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2023)
Review
Chemistry, Physical
Philippe Serp
Summary: Catalytic active sites composed of isolated metal single atoms are present in enzymatic, homogeneous, and heterogeneous catalysts. Single-atom catalysts (SACs) in heterogeneous catalysis have the potential to exhibit high reactivity and selectivity, provided that their local coordination environment and electronic properties are properly tuned. These sites possess distinctive properties compared to metal nanoparticles or clusters. Despite the challenges in achieving catalysts with high homogeneity of active sites in supported catalysis, a growing body of research has shown the potential synergy between these two species to enhance catalytic performance. This mini-review discusses the different types of synergies, as well as the challenges and opportunities for these catalysts in thermal, electro, and photo-catalysis.
Article
Chemistry, Physical
Jeremy Audevard, Javier Navarro-Ruiz, Vincent Bernardin, Yann Tison, Anna Corrias, Iker Del Rosal, Alain Favre-Reguillon, Regis Philippe, Iann C. Gerber, Philippe Serp
Summary: Pd/C catalysts are widely used in hydrogenation reactions, with Pd nanoparticles promoting H-spillover. However, in selective hydrogenation, unpromoted Pd/C catalysts are not effective. Pd single atom catalysts, although selective, have low activity. By utilizing a cooperative catalysis between Pd nanoparticles and Pd single atoms, high selectivity and activity can be achieved.
Article
Chemistry, Analytical
Josimar M. Batista, Maria J. Neves, Helvecio C. Menezes, Zenilda L. Cardeal
Summary: A new amino acid extraction method using functionalized magnetic carbon nanotubes was developed and optimized, which showed excellent extraction of analytes. Exposure of Saccharomyces cerevisiae to BaP at a concentration of 25.0 μmol L-1 caused changes in cell viability, indicating metabolic alterations. A fast and efficient GC/MS method was optimized to determine 16 amino acids in yeasts exposed or not to BaP. Comparison of amino acid concentrations revealed statistically significant differences in glycine, serine, phenylalanine, proline, asparagine, aspartic acid, glutamic acid, tyrosine, and leucine, suggesting their potential as toxicity biomarker candidates.
Review
Chemistry, Multidisciplinary
Canio Scarfiello, Doan Pham Minh, Katerina Soulantica, Philippe Serp
Summary: Carbon capture and utilization is a promising strategy to achieve global energy and climate goals. By catalytic hydrogenation of CO2 with renewable H-2, waste CO2 can be transformed into a chemical feedstock for valuable energy carriers and chemicals. CO2-Fischer-Tropsch synthesis-based hydrocarbons can contribute to a circular carbon economy and significantly impact anthropogenic emissions into the atmosphere.
ADVANCED MATERIALS INTERFACES
(2023)
Article
Chemistry, Applied
Vincent Bernardin, Laurent Vanoye, Camila Rivera-Careamo, Philippe Serp, Alain Favre-Reguillon, Regis Philippe
Summary: Understanding the cooperative action of palladium nanoparticles (NPs) and palladium single atoms (SAs) supported on Ni is essential for developing more efficient supported transition metal catalysts. This work compared a series of Pd-catalysts on CNTs with the same palladium loading but different SA/NP ratios and demonstrated a synergy between the two palladium species (SAs and NPs). The study also identified the optimal distribution of surface palladium for maximum activity in the chosen test reactions.
Article
Chemistry, Physical
Jeremy Audevard, Javier Navarro-Ruiz, Vincent Bernardin, Regis Philippe, Anna Corrias, Yann Tison, Alain Favre-Reguillon, Iker Del Rosal, Iann C. Gerber, Philippe Serp
Summary: Achieving high selectivity, conversion, and rate in the industrially important selective hydrogenation of a,b-unsaturated aldehydes is challenging. Previous approaches have sacrificed activity for selectivity towards unsaturated alcohol or saturated aldehyde. However, this study demonstrates that combining Ni nanoparticles (NiNP) and Ru single atoms (RuSA) on CNTs allows for improved hydrocinnamaldehyde selectivity without compromising activity. The resulting catalyst shows 94% selectivity at 99% conversion and has good stability in continuous flow conditions. Insights into the cooperative catalysis mechanism between NiNP and RuSA were obtained through density functional theory calculations.
JOURNAL OF CATALYSIS
(2023)
Article
Chemistry, Analytical
Lucas Almir Cavalcante Minho, Zenilda de Lourdes Cardeal, Helvecio Costa Menezes
Summary: In this study, an open-source program based on deep neural networks was developed to optimize chromatographic methods and simulate operating conditions outside the laboratory. The deep neural networks models successfully predicted the retention times of compounds in the first and second dimensions, showing good compliance with various chemical classes. However, continuous updates to the database are needed for accurate prediction of retention times of less common compounds, and the formation of a collaborative database is proposed.
JOURNAL OF SEPARATION SCIENCE
(2023)
Article
Chemistry, Analytical
Lucas Almir Cavalcante Minho, Zenilda de Lourdes Cardeal, Helvecio Costa Menezes
Summary: Reinforcing hollow polypropylene fibers with nanocellulose improves the extractive properties of microporous membranes, making them suitable for long-term sampling of water contaminants. The modified polypropylene hollow fiber grafted with nanocellulose was characterized using various analysis techniques. The miniaturized passive sampling devices equipped with the new material successfully identified a variety of pollutants in environmental waters.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Davide Salusso, Canio Scarfiello, Anna Efimenko, Doan Pham Minh, Philippe Serp, Katerina Soulantica, Spyridon Zafeiratos
Summary: The metal-support interaction is crucial for the performance of catalysts, and understanding its evolution under reactive gas atmospheres is important for catalyst design. In this study, the in situ restructuring of cobalt particles supported on TiO2 and the impact of gas phase environment were investigated using X-ray photoemission spectroscopy.
