Neuronal Polarity in the Embryonic Mammalian Cerebral Cortex

Rap1 GTPases Are Master Regulators of Neural Cell Polarity in the Developing Neocortex

(2016) Bhavin Shah et al.   CEREBRAL CORTEX

Dynamic mRNA Transport and Local Translation in Radial Glial Progenitors of the Developing Brain

(2016) Louis-Jan Pilaz et al.   CURRENT BIOLOGY

Rab GTPase signaling in neurite outgrowth and axon specification

(2016) David Villarroel-Campos et al.   Cytoskeleton

Ephrin Bs and canonical Reelin signalling

(2016) Theresa Pohlkamp et al.   NATURE

Reelin and Neuropsychiatric Disorders

(2016) Kazuhiro Ishii et al.   Frontiers in Cellular Neuroscience

Bidirectional radial Ca2+ activity regulates neurogenesis and migration during early cortical column formation

(2016) B. G. Rash et al.   Science Advances

Radial Glial Cell-Neuron Interaction Directs Axon Formation at the Opposite Side of the Neuron from the Contact Site

(2015) C. Xu et al.   JOURNAL OF NEUROSCIENCE

CRMPs: critical molecules for neurite morphogenesis and neuropsychiatric diseases

(2015) T T Quach et al.   MOLECULAR PSYCHIATRY

The Outer Subventricular Zone and Primate-Specific Cortical Complexification

(2015) Colette Dehay et al.   NEURON

Molecular Pathways Underlying Projection Neuron Production and Migration during Cerebral Cortical Development

(2015) Chiaki Ohtaka-Maruyama et al.   Frontiers in Neuroscience

Cortical and Clonal Contribution of Tbr2 Expressing Progenitors in the Developing Mouse Brain

(2014) Navneet A. Vasistha et al.   CEREBRAL CORTEX

The serotonin 6 receptor controls neuronal migration during corticogenesis via a ligand-independent Cdk5-dependent mechanism

(2014) M. Jacobshagen et al.   DEVELOPMENT

Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex

(2014) Yuki Hirota et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Proliferative Defects and Formation of a Double Cortex in Mice Lacking Mltt4 and Cdh2 in the Dorsal Telencephalon

(2014) C. Gil-Sanz et al.   JOURNAL OF NEUROSCIENCE

Glial Development: The Crossroads of Regeneration and Repair in the CNS

(2014) Vittorio Gallo et al.   NEURON

Pioneering Axons Regulate Neuronal Polarization in the Developing Cerebral Cortex

(2014) Takashi Namba et al.   NEURON

Development of Cortical Interneurons

(2014) Jianhua Chu et al.   NEUROPSYCHOPHARMACOLOGY

Small organelle, big responsibility: the role of centrosomes in development and disease

(2014) P. L. Chavali et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Prdm8 Regulates the Morphological Transition at Multipolar Phase during Neocortical Development

(2014) Mayuko Inoue et al.   PLoS One

TBC1D24 regulates neuronal migration and maturation through modulation of the ARF6-dependent pathway

(2014) Antonio Falace et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apical Abscission Alters Cell Polarity and Dismantles the Primary Cilium During Neurogenesis

(2014) R. M. Das et al.   SCIENCE

Molecules and mechanisms that regulate multipolar migration in the intermediate zone

(2014) Jonathan A. Cooper   Frontiers in Cellular Neuroscience

Asymmetric Inheritance of Centrosome-Associated Primary Cilium Membrane Directs Ciliogenesis after Cell Division

(2013) Judith T.M.L. Paridaen et al.   CELL

Dynamics of Centrosome Translocation and Microtubule Organization in Neocortical Neurons during Distinct Modes of Polarization

(2013) Akira Sakakibara et al.   CEREBRAL CORTEX

Lineage-dependent circuit assembly in the neocortex

(2013) Peng Gao et al.   DEVELOPMENT

Evidence for dysregulation of axonal growth and guidance in the etiology of ASD

(2013) Kathryn McFadden et al.   Frontiers in Human Neuroscience

Epigenetic regulation of neural stem cell fate during corticogenesis

(2013) Chai MuhChyi et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

c-Jun NH2-terminal Kinase (JNK)-interacting Protein-3 (JIP3) Regulates Neuronal Axon Elongation in a Kinesin- and JNK-dependent Manner

(2013) Tao Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ERK2-Mediated Phosphorylation of Par3 Regulates Neuronal Polarization

(2013) Y. Funahashi et al.   JOURNAL OF NEUROSCIENCE

Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition–like mechanism

(2013) Yasuhiro Itoh et al.   NATURE NEUROSCIENCE

Arl13b-regulated cilia activities are essential for polarized radial glial scaffold formation

(2013) Holden Higginbotham et al.   NATURE NEUROSCIENCE

Non-epithelial stem cells and cortical interneuron production in the human ganglionic eminences

(2013) David V Hansen et al.   NATURE NEUROSCIENCE

Subcortical origins of human and monkey neocortical interneurons

(2013) Tong Ma et al.   NATURE NEUROSCIENCE

Molecular logic of neocortical projection neuron specification, development and diversity

(2013) Luciano Custo Greig et al.   NATURE REVIEWS NEUROSCIENCE

Ephrin-B1 Controls the Columnar Distribution of Cortical Pyramidal Neurons by Restricting Their Tangential Migration

(2013) Jordane Dimidschstein et al.   NEURON

Cajal-Retzius Cells Instruct Neuronal Migration by Coincidence Signaling between Secreted and Contact-Dependent Guidance Cues

(2013) Cristina Gil-Sanz et al.   NEURON

BDNF and Schizophrenia: From Neurodevelopment to Neuronal Plasticity, Learning, and Memory

(2013) R. Nieto et al.   Frontiers in Psychiatry

Prefrontal cortex cytoarchitecture in normal aging and Alzheimer’s disease: a relationship with IQ

(2012) Susanne J. van Veluw et al.   Brain Structure & Function

Excitatory Cortical Neurons with Multipolar Shape Establish Neuronal Polarity by Forming a Tangentially Oriented Axon in the Intermediate Zone

(2012) Yumiko Hatanaka et al.   CEREBRAL CORTEX

OSVZ progenitors in the human cortex: an updated perspective on neurodevelopmental disease

(2012) Bridget E LaMonica et al.   CURRENT OPINION IN NEUROBIOLOGY

Cyclin D2 in the basal process of neural progenitors is linked to non-equivalent cell fates

(2012) Yuji Tsunekawa et al.   EMBO JOURNAL

N-cadherin specifies first asymmetry in developing neurons

(2012) Annette Gärtner et al.   EMBO JOURNAL

Reelin promotes microtubule dynamics in processes of developing neurons

(2012) Maurice Meseke et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Clonally related visual cortical neurons show similar stimulus feature selectivity

(2012) Ye Li et al.   NATURE

Preferential electrical coupling regulates neocortical lineage-dependent microcircuit assembly

(2012) Yong-Chun Yu et al.   NATURE

Reelin Controls Neuronal Positioning by Promoting Cell-Matrix Adhesion via Inside-Out Activation of Integrin α5β1

(2012) Katsutoshi Sekine et al.   NEURON

Foxp-Mediated Suppression of N-Cadherin Regulates Neuroepithelial Character and Progenitor Maintenance in the CNS

(2012) David L. Rousso et al.   NEURON

The involvement of Reelin in neurodevelopmental disorders

(2012) Timothy D. Folsom et al.   NEUROPHARMACOLOGY

Dab2ip Regulates Neuronal Migration and Neurite Outgrowth in the Developing Neocortex

(2012) Gum Hwa Lee et al.   PLoS One

Connexin 43 controls the multipolar phase of neuronal migration to the cerebral cortex

(2012) X. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development and Evolution of the Human Neocortex

(2011) Jan H. Lui et al.   CELL

Molecular Genetics of Neuronal Migration Disorders

(2011) Judy S. Liu   Current Neurology and Neuroscience Reports

What disorders of cortical development tell us about the cortex: one plus one does not always make two

(2011) M Chiara Manzini et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Basolateral rather than apical primary cilia on neuroepithelial cells committed to delamination

(2011) M. Wilsch-Brauninger et al.   DEVELOPMENT

Primary cilia and Gli3 activity regulate cerebral cortical size

(2011) Sandra L. Wilson et al.   Developmental Neurobiology

Cell-type-specific consequences of reelin deficiency in the mouse neocortex, hippocampus, and amygdala

(2011) Maureen P. Boyle et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Gli3 Is Required for Maintenance and Fate Specification of Cortical Progenitors

(2011) H. Wang et al.   JOURNAL OF NEUROSCIENCE

The Outermost Region of the Developing Cortical Plate Is Crucial for Both the Switch of the Radial Migration Mode and the Dab1-Dependent "Inside-Out" Lamination in the Neocortex

(2011) K. Sekine et al.   JOURNAL OF NEUROSCIENCE

Oblique Radial Glial Divisions in the Developing Mouse Neocortex Induce Self-Renewing Progenitors outside the Germinal Zone That Resemble Primate Outer Subventricular Zone Progenitors

(2011) A. Shitamukai et al.   JOURNAL OF NEUROSCIENCE

Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration

(2011) Aycan Sentürk et al.   NATURE

Cytokinesis remnants define first neuronal asymmetry in vivo

(2011) Giulia Pollarolo et al.   NATURE NEUROSCIENCE

Phosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rate

(2011) Nina Westerlund et al.   NATURE NEUROSCIENCE

Reelin, Rap1 and N-cadherin orient the migration of multipolar neurons in the developing neocortex

(2011) Yves Jossin et al.   NATURE NEUROSCIENCE

Cilia in the CNS: The Quiet Organelle Claims Center Stage

(2011) Angeliki Louvi et al.   NEURON

Proneural Transcription Factors Regulate Different Steps of Cortical Neuron Migration through Rnd-Mediated Inhibition of RhoA Signaling

(2011) Emilie Pacary et al.   NEURON

The Cerebrospinal Fluid Provides a Proliferative Niche for Neural Progenitor Cells

(2011) Maria K. Lehtinen et al.   NEURON

Local Application of Neurotrophins Specifies Axons Through Inositol 1,4,5-Trisphosphate, Calcium, and Ca2+/Calmodulin-Dependent Protein Kinases

(2011) S. Nakamuta et al.   Science Signaling

A systems-biology approach to understanding the ciliopathy disorders

(2011) Ji Eun Lee et al.   Genome Medicine

A Focal Epilepsy and Intellectual Disability Syndrome Is Due to a Mutation in TBC1D24

(2010) Mark A. Corbett et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Reelin and Stk25 Have Opposing Roles in Neuronal Polarization and Dendritic Golgi Deployment

(2010) Tohru Matsuki et al.   CELL

TGF-β Signaling Specifies Axons during Brain Development

(2010) Jason J. Yi et al.   CELL

The vertebrate retina: A model for neuronal polarization in vivo

(2010) Owen Randlett et al.   Developmental Neurobiology

The Suppression of CRMP2 Expression by Bone Morphogenetic Protein (BMP)-SMAD Gradient Signaling Controls Multiple Stages of Neuronal Development

(2010) Yiming Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cullin 5 Regulates Cortical Layering by Modulating the Speed and Duration of Dab1-Dependent Neuronal Migration

(2010) S. Simo et al.   JOURNAL OF NEUROSCIENCE

Centrosome Motility Is Essential for Initial Axon Formation in the Neocortex

(2010) F. C. de Anda et al.   JOURNAL OF NEUROSCIENCE

Neurogenic radial glia in the outer subventricular zone of human neocortex

(2010) David V. Hansen et al.   NATURE

Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture

(2010) Timothy W Yu et al.   NATURE GENETICS

WDR62 is associated with the spindle pole and is mutated in human microcephaly

(2010) Adeline K Nicholas et al.   NATURE GENETICS

OSVZ progenitors of human and ferret neocortex are epithelial-like and expand by integrin signaling

(2010) Simone A Fietz et al.   NATURE NEUROSCIENCE

The primary cilium: a signalling centre during vertebrate development

(2010) Sarah C. Goetz et al.   NATURE REVIEWS GENETICS

Adherens junctions: from molecules to morphogenesis

(2010) Tony J. C. Harris et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Apical Complex Couples Cell Fate and Cell Survival to Cerebral Cortical Development

(2010) Seonhee Kim et al.   NEURON

Rab GTPases-Dependent Endocytic Pathways Regulate Neuronal Migration and Maturation through N-Cadherin Trafficking

(2010) Takeshi Kawauchi et al.   NEURON

Axon Extension Occurs Independently of Centrosomal Microtubule Nucleation

(2010) M. Stiess et al.   SCIENCE

A Novel Role for Dbx1-Derived Cajal-Retzius Cells in Early Regionalization of the Cerebral Cortical Neuroepithelium

(2010) Amélie Griveau et al.   PLOS BIOLOGY

Mutations in STIL, Encoding a Pericentriolar and Centrosomal Protein, Cause Primary Microcephaly

(2009) Arun Kumar et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Retinoic Acid from the Meninges Regulates Cortical Neuron Generation

(2009) Julie A. Siegenthaler et al.   CELL

Intermediate Neuronal Progenitors (Basal Progenitors) Produce Pyramidal–Projection Neurons for All Layers of Cerebral Cortex

(2009) Tom Kowalczyk et al.   CEREBRAL CORTEX

Centriole Age Underlies Asynchronous Primary Cilium Growth in Mammalian Cells

(2009) Charles T. Anderson et al.   CURRENT BIOLOGY

Adherens junction domains are split by asymmetric division of embryonic neural stem cells

(2009) Véronique Marthiens et al.   EMBO REPORTS

Downregulation of Functional Reelin Receptors in Projection Neurons Implies That Primary Reelin Action Occurs atEarly/Premigratory Stages

(2009) T. Uchida et al.   JOURNAL OF NEUROSCIENCE

Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling

(2009) Masaaki Torii et al.   NATURE

Asymmetric centrosome inheritance maintains neural progenitors in the neocortex

(2009) Xiaoqun Wang et al.   NATURE

Specific synapses develop preferentially among sister excitatory neurons in the neocortex

(2009) Yong-Chun Yu et al.   NATURE

Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors

(2009) Eve Seuntjens et al.   NATURE NEUROSCIENCE

Expanding the clinical and neuroradiologic phenotype of primary microcephaly due to ASPM mutations

(2009) S. Passemard et al.   NEUROLOGY

SUN1/2 and Syne/Nesprin-1/2 Complexes Connect Centrosome to the Nucleus during Neurogenesis and Neuronal Migration in Mice

(2009) Xiaochang Zhang et al.   NEURON

Mammalian Par3 Regulates Progenitor Cell Asymmetric Division via Notch Signaling in the Developing Neocortex

(2009) Ronald S. Bultje et al.   NEURON

Neuronal Polarity

(2009) S. Tahirovic et al.   Cold Spring Harbor Perspectives in Biology

The JIP1 Scaffold Protein Regulates Axonal Development in Cortical Neurons

(2008) Federico Dajas-Bailador et al.   CURRENT BIOLOGY

Cytokinesis of neuroepithelial cells can divide their basal process before anaphase

(2008) Yoichi Kosodo et al.   EMBO JOURNAL

Eph/ephrin signaling: networks

(2008) D. Arvanitis et al.   GENES & DEVELOPMENT

Convergent evidence identifying MAP/microtubule affinity-regulating kinase 1 (MARK1) as a susceptibility gene for autism

(2008) G. Maussion et al.   HUMAN MOLECULAR GENETICS

Distinct behaviors of neural stem and progenitor cells underlie cortical neurogenesis

(2008) Stephen C. Noctor et al.   JOURNAL OF COMPARATIVE NEUROLOGY

c-Jun N-terminal kinases trigger both degeneration and neurite outgrowth in primary hippocampal and cortical neurons

(2008) S. Eminel et al.   JOURNAL OF NEUROCHEMISTRY

Accurate Balance of the Polarity Kinase MARK2/Par-1 Is Required for Proper Cortical Neuronal Migration

(2008) T. Sapir et al.   JOURNAL OF NEUROSCIENCE

Tbr2 Directs Conversion of Radial Glia into Basal Precursors and Guides Neuronal Amplification by Indirect Neurogenesis in the Developing Neocortex

(2008) Alessandro Sessa et al.   NEURON

Mutations in the Pericentrin (PCNT) Gene Cause Primordial Dwarfism

(2008) A. Rauch et al.   SCIENCE

Brain IGF-1 Receptors Control Mammalian Growth and Lifespan through a Neuroendocrine Mechanism

(2008) Laurent Kappeler et al.   PLOS BIOLOGY