Social Isolation in Early versus Late Adolescent Mice Is Associated with Persistent Behavioral Deficits That Can Be Improved by Neurosteroid-Based Treatment

Brexanolone (SAGE-547 injection) in post-partum depression: a randomised controlled trial

(2017) Stephen Kanes et al.   LANCET

Neuroactive steroids and PTSD treatment

(2017) Ann M. Rasmusson et al.   NEUROSCIENCE LETTERS

Neurosteroids and potential therapeutics: Focus on pregnenolone

(2016) Monique Vallée   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Childhood trauma predicts antidepressant response in adults with major depression: data from the randomized international study to predict optimized treatment for depression

(2016) L M Williams et al.   Translational Psychiatry

Improving the Prediction of Treatment Response in Depression: Integration of Clinical, Cognitive, Psychophysiological, Neuroimaging, and Genetic Measures

(2016) Andrew H. Kemp et al.   CNS SPECTRUMS

Anxiolytic-like effects of YL-IPA08, a potent ligand for the translocator protein (18 kDa) in animal models of post-traumatic stress disorder

(2014) Li-Ming Zhang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Short communication - N-palmitoylethanolamide, an endocannabinoid, exhibits antidepressant effects in the forced swim test and the tail suspension test in mice

(2014) Hai-Ling Yu et al.   Pharmacological Reports

5α-reductase type I expression is downregulated in the prefrontal cortex/Brodmann’s area 9 (BA9) of depressed patients

(2014) Roberto Carlos Agis-Balboa et al.   PSYCHOPHARMACOLOGY

Pregnenolone Can Protect the Brain from Cannabis Intoxication

(2014) Monique Vallée et al.   SCIENCE

Ganaxolone improves behavioral deficits in a mouse model of post-traumatic stress disorder

(2014) Graziano Pinna et al.   Frontiers in Cellular Neuroscience

A Neurobiological Hypothesis of Treatment-Resistant Depression – Mechanisms for Selective Serotonin Reuptake Inhibitor Non-Efficacy

(2014) Jeremy D. Coplan et al.   Frontiers in Behavioral Neuroscience

Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010

(2013) Harvey A Whiteford et al.   LANCET

Expression of GABAA α2-, β1- and ɛ-receptors are altered significantly in the lateral cerebellum of subjects with schizophrenia, major depression and bipolar disorder

(2013) S H Fatemi et al.   Translational Psychiatry

Mechanisms of antidepressant resistance

(2013) Wissam El-Hage et al.   Frontiers in Pharmacology

The neurobiology of depression and antidepressant action

(2012) Paul Willner et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Childhood Maltreatment Predicts Unfavorable Course of Illness and Treatment Outcome in Depression: A Meta-Analysis

(2011) Valentina Nanni et al.   AMERICAN JOURNAL OF PSYCHIATRY

Evidence-based pharmacotherapy of post-traumatic stress disorder (PTSD)

(2011) Jonathan C. Ipser et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Impact of Physical and Sexual Abuse on Treatment Response in the Treatment of Resistant Depression in Adolescent Study (TORDIA)

(2011) Wael Shamseddeen et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Implication of allopregnanolone in the antinociceptive effect of N-palmitoylethanolamide in acute or persistent pain

(2011) Oscar Sasso et al.   PAIN

Neurosteroids reduce social isolation-induced behavioral deficits: a proposed link with neurosteroid-mediated upregulation of BDNF expression

(2011) Mauricio Nin   Frontiers in Endocrinology

The GABAergic deficit hypothesis of major depressive disorder

(2010) B Luscher et al.   MOLECULAR PSYCHIATRY

S-norfluoxetine microinfused into the basolateral amygdala increases allopregnanolone levels and reduces aggression in socially isolated mice

(2010) Marianela Nelson et al.   NEUROPHARMACOLOGY

Effects of Duloxetine in Treatment-Refractory Men with Posttraumatic Stress Disorder

(2010) E. Walderhaug et al.   PHARMACOPSYCHIATRY

SSRIs act as selective brain steroidogenic stimulants (SBSSs) at low doses that are inactive on 5-HT reuptake

(2009) Graziano Pinna et al.   CURRENT OPINION IN PHARMACOLOGY

The Importance of Childhood Trauma and Childhood Life Events for Chronicity of Depression in Adults

(2009) Jenneke E. Wiersma et al.   JOURNAL OF CLINICAL PSYCHIATRY

Global Brain Gene Expression Analysis Links Glutamatergic and GABAergic Alterations to Suicide and Major Depression

(2009) Adolfo Sequeira et al.   PLoS One

Understanding the Pathophysiology of Postpartum Depression: Implications for the Development of Novel Treatments

(2008) Charles B. Nemeroff   NEURON

Decreased corticolimbic allopregnanolone expression during social isolation enhances contextual fear: A model relevant for posttraumatic stress disorder

(2008) F. Pibiri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA