Connexin-Dependent Neuroglial Networking as a New Therapeutic Target

Barreloid Borders and Neuronal Activity Shape Panglial Gap Junction-Coupled Networks in the Mouse Thalamus

(2016) Lena Claus et al.   CEREBRAL CORTEX

Treatment Options for Narcolepsy

(2016) Lucie Barateau et al.   CNS DRUGS

Repression of Astrocytic Connexins in Cortical and Subcortical Brain Regions and Prefrontal Enrichment of H3K9me3 in Depression and Suicide

(2016) Corina Nagy et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Connexin-based channels contribute to metabolic pathways in the oligodendroglial lineage

(2016) Jianqin Niu et al.   JOURNAL OF CELL SCIENCE

Bridging the gap to therapeutic strategies based on connexin/pannexin biology

(2016) Christian C. Naus et al.   Journal of Translational Medicine

Crucial role of astrocytes in temporal lobe epilepsy

(2016) C. Steinhäuser et al.   NEUROSCIENCE

Regulation of neuron–astrocyte metabolic coupling across the sleep–wake cycle

(2016) J.-M. Petit et al.   NEUROSCIENCE

The homeostatic astroglia emerges from evolutionary specialization of neural cells

(2016) Alexei Verkhratsky et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Astrocytes regulate cortical state switching in vivo

(2016) Kira E. Poskanzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocytes as new targets to improve cognitive functions

(2016) Glenn Dallérac et al.   PROGRESS IN NEUROBIOLOGY

Astroglial networks promote neuronal coordination

(2016) Oana Chever et al.   Science Signaling

Glial Gap Junctions Boost Modafinil Action on Arousal

(2016) Jun Lu et al.   SLEEP

Impact of Astroglial Connexins on Modafinil Pharmacological Properties

(2016) Adeline Duchêne et al.   SLEEP

Antidepressants Impact Connexin 43 Channel Functions in Astrocytes

(2016) Tiffany Jeanson et al.   Frontiers in Cellular Neuroscience

Astroglial networks promote neuronal coordination

(2016) Oana Chever et al.   Science Signaling

Glial Gap Junctions Boost Modafinil Action on Arousal

(2016) Jun Lu et al.   SLEEP

Impact of Astroglial Connexins on Modafinil Pharmacological Properties

(2016) Adeline Duchêne et al.   SLEEP

Potentiation of Amitriptyline Anti-Hyperalgesic-Like Action By Astroglial Connexin 43 Inhibition in Neuropathic Rats

(2016) Tiffany Jeanson et al.   Scientific Reports

Respective pharmacological features of neuropathic-like pain evoked by intrathecal BDNF versus sciatic nerve ligation in rats

(2015) Saïd M’Dahoma et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

General anesthetics have differential inhibitory effects on gap junction channels and hemichannels in astrocytes and neurons

(2015) Xinhe Liu et al.   GLIA

Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis

(2015) Nanna B Finnerup et al.   LANCET NEUROLOGY

Attenuated Levels of Hippocampal Connexin 43 and its Phosphorylation Correlate with Antidepressant- and Anxiolytic-Like Activities in Mice

(2015) Gaël Quesseveur et al.   Frontiers in Cellular Neuroscience

Potential primary roles of glial cells in the mechanisms of psychiatric disorders

(2015) Kazuhiko Yamamuro et al.   Frontiers in Cellular Neuroscience

The dual face of connexin-based astroglial Ca2+ communication: A key player in brain physiology and a prime target in pathology

(2014) Marijke De Bock et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Amitriptyline up-regulates connexin43-gap junction in rat cultured cortical astrocytes via activation of the p38 and c-Fos/AP-1 signalling pathway

(2014) N Morioka et al.   BRITISH JOURNAL OF PHARMACOLOGY

Characterization of Panglial Gap Junction Networks in the Thalamus, Neocortex, and Hippocampus Reveals a Unique Population of Glial Cells

(2014) Stephanie Griemsmann et al.   CEREBRAL CORTEX

Reduced connexin 43 immunolabeling in the orbitofrontal cortex in alcohol dependence and depression

(2014) José Javier Miguel-Hidalgo et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Connexin 30 sets synaptic strength by controlling astroglial synapse invasion

(2014) Ulrike Pannasch et al.   NATURE NEUROSCIENCE

Roles of gap junctions, connexins, and pannexins in epilepsy

(2014) Shanthini Mylvaganam et al.   Frontiers in Physiology

Hemichannels: new roles in astroglial function

(2014) Juan A. Orellana et al.   Frontiers in Physiology

Forebrain Engraftment by Human Glial Progenitor Cells Enhances Synaptic Plasticity and Learning in Adult Mice

(2013) Xiaoning Han et al.   Cell Stem Cell

Glia and epilepsy: Experimental investigation of antiepileptic drugs in an astroglia/microglia co-culture model of inflammation

(2013) Hannes Dambach et al.   EPILEPSIA

Astrocyte-restricted disruption of connexin-43 impairs neuronal plasticity in mouse barrel cortex

(2013) Yong Han et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The psychostimulant modafinil enhances gap junctional communication in cortical astrocytes

(2013) Xinhe Liu et al.   NEUROPHARMACOLOGY

Astrocytic Cx43 and Cx30 differentially modulate adult neurogenesis in mice

(2013) Marie Liebmann et al.   NEUROSCIENCE LETTERS

Emerging role for astroglial networks in information processing: from synapse to behavior

(2013) Ulrike Pannasch et al.   TRENDS IN NEUROSCIENCES

Connexin and pannexin hemichannels in brain glial cells: properties, pharmacology, and roles

(2013) Christian Giaume et al.   Frontiers in Pharmacology

Curious and contradictory roles of glial connexins and pannexins in epilepsy

(2012) Peter L. Carlen   BRAIN RESEARCH

Astrocytic CX43 hemichannels and gap junctions play a crucial role in development of chronic neuropathic pain following spinal cord injury

(2012) Michael J. Chen et al.   GLIA

Intercellular Ca2+ Waves: Mechanisms and Function

(2012) Luc Leybaert et al.   PHYSIOLOGICAL REVIEWS

Astrocyte regulation of sleep circuits: experimental and modeling perspectives

(2012) Tommaso Fellin et al.   Frontiers in Computational Neuroscience

Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation

(2011) Mireille Bélanger et al.   Cell Metabolism

Ablation of connexin30 in transgenic mice alters expression patterns of connexin26 and connexin32 in glial cells and leptomeninges

(2011) B. D. Lynn et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

From a glial syncytium to a more restricted and specific glial networking

(2011) Christian Giaume et al.   JOURNAL OF PHYSIOLOGY-PARIS

Cx32 and Cx47 mediate oligodendrocyte:astrocyte and oligodendrocyte:oligodendrocyte gap junction coupling

(2011) Sameh K. Wasseff et al.   NEUROBIOLOGY OF DISEASE

Gap Junction Dysfunction in the Prefrontal Cortex Induces Depressive-Like Behaviors in Rats

(2011) Jian-Dong Sun et al.   NEUROPSYCHOPHARMACOLOGY

Sleep deprivation and sleep recovery modifies connexin36 and connexin43 protein levels in rat brain

(2011) Javier Franco-Pérez et al.   NEUROREPORT

Astroglial networks scale synaptic activity and plasticity

(2011) U. Pannasch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasticity of astroglial networks in olfactory glomeruli

(2011) L. Roux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocytic regulation of cortical UP states

(2011) K. E. Poskanzer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astroglial networks: a step further in neuroglial and gliovascular interactions

(2010) Christian Giaume et al.   NATURE REVIEWS NEUROSCIENCE

Deletion of Astrocyte Connexins 43 and 30 Leads to a Dysmyelinating Phenotype and Hippocampal CA1 Vacuolation

(2009) S. E. Lutz et al.   JOURNAL OF NEUROSCIENCE

Modulation of Brain Hemichannels and Gap Junction Channels by Pro-Inflammatory Agents and Their Possible Role in Neurodegeneration

(2008) Juan A. Orellana et al.   ANTIOXIDANTS & REDOX SIGNALING

Differential NMDA-dependent activation of glial cells in mouse hippocampus

(2008) Alexandre Serrano et al.   GLIA

Neurons control the expression of connexin 30 and connexin 43 in mouse cortical astrocytes

(2008) Annette Koulakoff et al.   GLIA

Gap Junction-Mediated Astrocytic Networks in the Mouse Barrel Cortex

(2008) V. Houades et al.   JOURNAL OF NEUROSCIENCE

Implications of antiinflammatory properties of the anticonvulsant drug levetiracetam in astrocytes

(2008) Aiden Haghikia et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Chronic psychotropic drug treatment causes differential expression of connexin 43 and GFAP in frontal cortex of rats

(2008) S. Hossein Fatemi et al.   SCHIZOPHRENIA RESEARCH

Astroglial Metabolic Networks Sustain Hippocampal Synaptic Transmission

(2008) N. Rouach et al.   SCIENCE

Expression of astrocytic markers aquaporin 4 and connexin 43 is altered in brains of subjects with autism

(2008) S. Hossein Fatemi et al.   SYNAPSE

Neuroglia: the 150 years after

(2008) Helmut Kettenmann et al.   TRENDS IN NEUROSCIENCES