Zirconium tetraazamacrocycle complexes display extraordinary stability and provide a new strategy for zirconium-89-based radiopharmaceutical development

Comparison of the octadentate bifunctional chelator DFO*-pPhe-NCS and the clinically used hexadentate bifunctional chelator DFO-pPhe-NCS for 89Zr-immuno-PET

(2016) Danielle J. Vugts et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Evaluation of a 3-hydroxypyridin-2-one (2,3-HOPO) Based Macrocyclic Chelator for 89Zr4+ and Its Use for ImmunoPET Imaging of HER2 Positive Model of Ovarian Carcinoma in Mice

(2016) Jeff N.Tinianow et al.   Theranostics

Preliminary Therapy Evaluation of 225Ac-DOTA-c(RGDyK) Demonstrates that Cerenkov Radiation Derived from 225Ac Daughter Decay Can Be Detected by Optical Imaging for In Vivo Tumor Visualization

(2016) Darpan N. Pandya et al.   Theranostics

Macrocycle-Based Hydroxamate Ligands for Complexation and Immunoconjugation of89Zirconium for Positron Emission Tomography (PET) Imaging

(2016) Eszter Boros et al.   ChemPlusChem

p-SCN-Bn-HOPO: A Superior Bifunctional Chelator for 89Zr ImmunoPET

(2015) Melissa A. Deri et al.   BIOCONJUGATE CHEMISTRY

Radionuclide Therapy of Unresectable Tumors with AvidinOX and90Y-biotinDOTA: Tongue Cancer Paradigm

(2015) Claudio Albertoni et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Di-macrocyclic terephthalamide ligands as chelators for the PET radionuclide zirconium-89

(2015) Darpan N. Pandya et al.   CHEMICAL COMMUNICATIONS

Reactions of heteroallenes with cyclam-based Zr(iv) complexes

(2015) Luis G. Alves et al.   DALTON TRANSACTIONS

Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with 89Zr4+: comparison with desferrioxamine-B

(2015) Michelle T. Ma et al.   DALTON TRANSACTIONS

Synthesis and Structural Study of Tetravalent (Zr4+, Hf4+, Ce4+, Th4+, U4+) Metal Complexes with Cyclic Hydroxamic Acids

(2015) Pawel Jewula et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Hydroxypyridinonate Complex Stability of Group (IV) Metals and Tetravalent f-Block Elements: The Key to the Next Generation of Chelating Agents for Radiopharmaceuticals

(2015) Manuel Sturzbecher-Hoehne et al.   INORGANIC CHEMISTRY

Evaluation of 68Ga- and 177Lu-DOTA-PEG4-LLP2A for VLA-4-Targeted PET Imaging and Treatment of Metastatic Melanoma

(2015) Wissam Beaino et al.   MOLECULAR PHARMACEUTICS

Novel Bifunctional Cyclic Chelator for 89Zr Labeling–Radiolabeling and Targeting Properties of RGD Conjugates

(2015) Chuangyan Zhai et al.   MOLECULAR PHARMACEUTICS

An octadentate bifunctional chelating agent for the development of stable zirconium-89 based molecular imaging probes

(2014) Malay Patra et al.   CHEMICAL COMMUNICATIONS

Rational Design, Synthesis, and Evaluation of Tetrahydroxamic Acid Chelators for Stable Complexation of Zirconium(IV)

(2014) François Guérard et al.   CHEMISTRY-A EUROPEAN JOURNAL

Renal Control of Calcium, Phosphate, and Magnesium Homeostasis

(2014) J. Blaine et al.   Clinical Journal of the American Society of Nephrology

Charting the mechanism and reactivity of zirconium oxalate with hydroxamate ligands using density functional theory: implications in new chelate design

(2014) Jason P. Holland et al.   DALTON TRANSACTIONS

Alternative Chelator for 89Zr Radiopharmaceuticals: Radiolabeling and Evaluation of 3,4,3-(LI-1,2-HOPO)

(2014) Melissa A. Deri et al.   JOURNAL OF MEDICINAL CHEMISTRY

Efficient 1-Step Radiolabeling of Monoclonal Antibodies to High Specific Activity with 225Ac for  -Particle Radioimmunotherapy of Cancer

(2014) W. F. Maguire et al.   JOURNAL OF NUCLEAR MEDICINE

A Modular Labeling Strategy for In Vivo PET and Near-Infrared Fluorescence Imaging of Nanoparticle Tumor Targeting

(2014) C. Perez-Medina et al.   JOURNAL OF NUCLEAR MEDICINE

Radiation Dosimetry Study of [89Zr]rituximab Tracer for Clinical Translation of B cell NHL Imaging using Positron Emission Tomography

(2014) Arutselvan Natarajan et al.   MOLECULAR IMAGING AND BIOLOGY

Desferrioxamine as an appropriate chelator for 90Nb: Comparison of its complexation properties for M-Df-Octreotide (M=Nb, Fe, Ga, Zr)

(2014) Valery Radchenko et al.   NUCLEAR MEDICINE AND BIOLOGY

Zirconium-89 Labeled Antibodies: A New Tool for Molecular Imaging in Cancer Patients

(2014) Floor C. J. van de Watering et al.   Biomed Research International

Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis

(2014) Brian M. Zeglis et al.   ChemistryOpen

Enzyme-Mediated Methodology for the Site-Specific Radiolabeling of Antibodies Based on Catalyst-Free Click Chemistry

(2013) Brian M. Zeglis et al.   BIOCONJUGATE CHEMISTRY

Matching chelators to radiometals for radiopharmaceuticals

(2013) Eric W. Price et al.   CHEMICAL SOCIETY REVIEWS

H6phospa-trastuzumab: bifunctional methylenephosphonate-based chelator with89Zr,111In and177Lu

(2013) Eric W. Price et al.   DALTON TRANSACTIONS

Highly Thermally Stable Eight-Coordinate Dichloride Zirconium Complexes Supported by Tridentate [ONN] Ligands: Syntheses, Characterization, and Ethylene Polymerization Behavior

(2013) Aike Li et al.   ORGANOMETALLICS

Investigation of Zr(iv) and89Zr(iv) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging

(2012) François Guérard et al.   CHEMICAL COMMUNICATIONS

Synthesis and structural characterization of novel cyclam-based zirconium complexes and their use in the controlled ROP of rac-lactide: access to cyclam-functionalized polylactide materials

(2012) Luis G. Alves et al.   DALTON TRANSACTIONS

Biodistribution, radiation dosimetry and scouting of 90Y-ibritumomab tiuxetan therapy in patients with relapsed B-cell non-Hodgkin’s lymphoma using 89Zr-ibritumomab tiuxetan and PET

(2012) Saiyada N. F. Rizvi et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Characterisation of organic matter associated with groundwater arsenic in reducing aquifers of southwestern Taiwan

(2012) Wafa M. Al Lawati et al.   JOURNAL OF HAZARDOUS MATERIALS

PET imaging with 89Zr: From radiochemistry to the clinic

(2012) Melissa A. Deri et al.   NUCLEAR MEDICINE AND BIOLOGY

Synthesis, Cu(ii) complexation,64Cu-labeling and biological evaluation of cross-bridged cyclam chelators with phosphonate pendant arms

(2011) Riccardo Ferdani et al.   DALTON TRANSACTIONS

Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease

(2010) Thaddeus J. Wadas et al.   CHEMICAL REVIEWS

89Zr-DFO-J591 for ImmunoPET of Prostate-Specific Membrane Antigen Expression In Vivo

(2010) J. P. Holland et al.   JOURNAL OF NUCLEAR MEDICINE

MicroPET Imaging of Integrin αvβ3 Expressing Tumors Using 89Zr-RGD Peptides

(2010) Orit Jacobson et al.   MOLECULAR IMAGING AND BIOLOGY

Synthesis and structural studies of amido, hydrazido and imido zirconium(iv) complexes incorporating a diamido/diamine cyclam-based ligand

(2009) Rui F. Munhá et al.   DALTON TRANSACTIONS

Standardized methods for the production of high specific-activity zirconium-89

(2009) Jason P. Holland et al.   NUCLEAR MEDICINE AND BIOLOGY