Evolved polymerases facilitate selection of fully 2′-OMe-modified aptamers

Selection of 2′-Fluoro-Modified Aptamers with Optimized Properties

(2017) Deepak Thirunavukarasu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The expanding world of DNA and RNA

(2016) Tingjian Chen et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Evolution of thermophilic DNA polymerases for the recognition and amplification of C2ʹ-modified DNA

(2016) Tingjian Chen et al.   Nature Chemistry

Highly stable aptamers selected from a 2′-fully modified fGmH RNA library for targeting biomaterials

(2015) Adam D. Friedman et al.   BIOMATERIALS

Modern affinity reagents: Recombinant antibodies and aptamers

(2015) Katherine Groff et al.   BIOTECHNOLOGY ADVANCES

Transcription yield of fully 2′-modified RNA can be increased by the addition of thermostabilizing mutations to T7 RNA polymerase mutants

(2015) Adam J. Meyer et al.   NUCLEIC ACIDS RESEARCH

Highly accurate synthesis of the fully 2′-fluoro-modified oligonucleotide by Therminator DNA polymerases

(2014) Takeshi Kasuya et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Identification of a T7 RNA polymerase variant that permits the enzymatic synthesis of fully 2′-O-methyl-modified RNA

(2013) Jenny Ibach et al.   JOURNAL OF BIOTECHNOLOGY

Aptamers can Discriminate Alkaline Proteins with High Specificity

(2011) Hanyang Yu et al.   CHEMBIOCHEM

Molecular Imaging with Nucleic Acid Aptamers

(2011) H. Hong et al.   CURRENT MEDICINAL CHEMISTRY

Aptamers as therapeutics

(2010) Anthony D. Keefe et al.   NATURE REVIEWS DRUG DISCOVERY

SELEX with modified nucleotides

(2008) Anthony D Keefe et al.   CURRENT OPINION IN CHEMICAL BIOLOGY