Single particle tracking-based reaction progress kinetic analysis reveals a series of molecular mechanisms of cetuximab-induced EGFR processes in a single living cell

Live-cell single-molecule tracking reveals co-recognition of H3K27me3 and DNA targets polycomb Cbx7-PRC1 to chromatin

(2016) Chao Yu Zhen et al.   eLife

Analysis of Interactions between the Epidermal Growth Factor Receptor and Soluble Ligands on the Basis of Single-Molecule Diffusivity in the Membrane of Living Cells

(2015) Do-Hyeon Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanistic insights into EGFR membrane clustering revealed by super-resolution imaging

(2015) Jing Gao et al.   Nanoscale

Dynamics of CRISPR-Cas9 genome interrogation in living cells

(2015) Spencer C. Knight et al.   SCIENCE

Probing the target search of DNA-binding proteins in mammalian cells using TetR as model searcher

(2015) Davide Normanno et al.   Nature Communications

Asymmetric PTEN Distribution Regulated by Spatial Heterogeneity in Membrane-Binding State Transitions

(2013) Satomi Matsuoka et al.   PLoS Computational Biology

Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesions

(2012) Olivier Rossier et al.   NATURE CELL BIOLOGY

Rational design of true monomeric and bright photoactivatable fluorescent proteins

(2012) Mingshu Zhang et al.   NATURE METHODS

Inferring diffusion in single live cells at the single-molecule level

(2012) A. Robson et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Cytoskeletal Control of CD36 Diffusion Promotes Its Receptor and Signaling Function

(2011) Khuloud Jaqaman et al.   CELL

Role of the Clathrin Terminal Domain in Regulating Coated Pit Dynamics Revealed by Small Molecule Inhibition

(2011) Lisa von Kleist et al.   CELL

Single-molecule analysis reveals three phases of DNA degradation by an exonuclease

(2011) Gwangrog Lee et al.   Nature Chemical Biology

Interfacial enzyme kinetics of a membrane bound kinase analyzed by real-time MAS-NMR

(2011) Sandra J Ullrich et al.   Nature Chemical Biology

Pre-existing clusters of the adaptor Lat do not participate in early T cell signaling events

(2011) David J Williamson et al.   NATURE IMMUNOLOGY

Molecular mechanism and physiological functions of clathrin-mediated endocytosis

(2011) Harvey T. McMahon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nimotuzumab, a promising therapeutic monoclonal for treatment of tumors of epithelial origin

(2010) Melarkode S. Ramakrishnan et al.   mAbs

Spatial control of EGF receptor activation by reversible dimerization on living cells

(2010) Inhee Chung et al.   NATURE

Nimotuzumab, an Antitumor Antibody that Targets the Epidermal Growth Factor Receptor, Blocks Ligand Binding while Permitting the Active Receptor Conformation

(2009) A. Talavera et al.   CANCER RESEARCH

Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer

(2009) Eric Van Cutsem et al.   NEW ENGLAND JOURNAL OF MEDICINE

Subdiffraction-Resolution Fluorescence Imaging with Conventional Fluorescent Probes

(2008) Mike Heilemann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Actin restricts FcɛRI diffusion and facilitates antigen-induced receptor immobilization

(2008) Nicholas L. Andrews et al.   NATURE CELL BIOLOGY

High-density mapping of single-molecule trajectories with photoactivated localization microscopy

(2008) Suliana Manley et al.   NATURE METHODS