Human Papillomavirus and the DNA Damage Response: Exploiting Host Repair Pathways for Viral Replication

FANCD2 Binds Human Papillomavirus Genomes and Associates with a Distinct Set of DNA Repair Proteins to Regulate Viral Replication

(2017) Chelsey C. Spriggs et al.   mBio

Human papillomavirus in oropharyngeal cancer: The changing face of a disease

(2016) Jon Mallen-St Clair et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Human Papillomavirus–Associated Cancers — United States, 2008–2012

(2016) Laura J. Viens et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling

(2015) L. E. Romick-Rosendale et al.   CLINICAL CANCER RESEARCH

Homologous Recombination Repair Factors Rad51 and BRCA1 Are Necessary for Productive Replication of Human Papillomavirus 31

(2015) William H. Chappell et al.   JOURNAL OF VIROLOGY

The Acetyltransferase Tip60 Is a Critical Regulator of the Differentiation-Dependent Amplification of Human Papillomaviruses

(2015) Shiyuan Hong et al.   JOURNAL OF VIROLOGY

ATM and ATR as therapeutic targets in cancer

(2015) Anika Maria Weber et al.   PHARMACOLOGY & THERAPEUTICS

The Role of the DNA Damage Response throughout the Papillomavirus Life Cycle

(2015) Caleb McKinney et al.   Viruses-Basel

Modulation of DNA Damage and Repair Pathways by Human Tumour Viruses

(2015) Robert Hollingworth et al.   Viruses-Basel

STAT-5 Regulates Transcription of the Topoisomerase IIβ-Binding Protein 1 (TopBP1) Gene To Activate the ATR Pathway and Promote Human Papillomavirus Replication

(2015) Shiyuan Hong et al.   mBio

The Deacetylase Sirtuin 1 Regulates Human Papillomavirus Replication by Modulating Histone Acetylation and Recruitment of DNA Damage Factors NBS1 and Rad51 to Viral Genomes

(2015) Erika S. Langsfeld et al.   PLoS Pathogens

Human Papillomaviruses Activate and Recruit SMC1 Cohesin Proteins for the Differentiation-Dependent Life Cycle through Association with CTCF Insulators

(2015) Kavi Mehta et al.   PLoS Pathogens

Productive Replication of Human Papillomavirus 31 Requires DNA Repair Factor Nbs1

(2014) D. C. Anacker et al.   JOURNAL OF VIROLOGY

Co-opting the Fanconi Anemia Genomic Stability Pathway Enables Herpesvirus DNA Synthesis and Productive Growth

(2014) Heidi Karttunen et al.   MOLECULAR CELL

Manipulation of cellular DNA damage repair machinery facilitates propagation of human papillomaviruses

(2014) Nicholas A. Wallace et al.   SEMINARS IN CANCER BIOLOGY

SV40 Utilizes ATM Kinase Activity to Prevent Non-homologous End Joining of Broken Viral DNA Replication Products

(2014) Gregory A. Sowd et al.   PLoS Pathogens

Human Papillomavirus Episome Stability Is Reduced by Aphidicolin and Controlled by DNA Damage Response Pathways

(2013) T. G. Edwards et al.   JOURNAL OF VIROLOGY

The SMC1-SMC3 cohesin heterodimer structures DNA through supercoiling-dependent loop formation

(2013) Mingxuan Sun et al.   NUCLEIC ACIDS RESEARCH

Evolution of cervical cancer screening and prevention in United States and Canada: Implications for public health practitioners and clinicians

(2013) M. Saraiya et al.   PREVENTIVE MEDICINE

Papillomaviruses Use Recombination-Dependent Replication to Vegetatively Amplify Their Genomes in Differentiated Cells

(2013) Nozomi Sakakibara et al.   PLoS Pathogens

DNA viruses and the cellular DNA-damage response

(2012) A. S. Turnell et al.   JOURNAL OF GENERAL VIROLOGY

The Fanconi Anemia Pathway Limits Human Papillomavirus Replication

(2012) E. E. Hoskins et al.   JOURNAL OF VIROLOGY

Engagement of the ATR-Dependent DNA Damage Response at the Human Papillomavirus 18 Replication Centers during the Initial Amplification

(2012) T. Reinson et al.   JOURNAL OF VIROLOGY

Human Papillomaviruses Recruit Cellular DNA Repair and Homologous Recombination Factors to Viral Replication Centers

(2012) K. A. Gillespie et al.   JOURNAL OF VIROLOGY

The Biology and Life-Cycle of Human Papillomaviruses

(2012) John Doorbar et al.   VACCINE

Cellular transformation by human papillomaviruses: Lessons learned by comparing high- and low-risk viruses

(2012) Aloysius J. Klingelhutz et al.   VIROLOGY

HPV 5 and 8 E6 Abrogate ATR Activity Resulting in Increased Persistence of UVB Induced DNA Damage

(2012) Nicholas A. Wallace et al.   PLoS Pathogens

Conserved Herpesvirus Kinases Target the DNA Damage Response Pathway and TIP60 Histone Acetyltransferase to Promote Virus Replication

(2011) Renfeng Li et al.   Cell Host & Microbe

The Papillomavirus E1 Helicase Activates a Cellular DNA Damage Response in Viral Replication Foci

(2011) N. Sakakibara et al.   JOURNAL OF VIROLOGY

The FANC pathway is activated by adenovirus infection and promotes viral replication-dependent recombination

(2011) Gioia Cherubini et al.   NUCLEIC ACIDS RESEARCH

Cohesin: a regulator of genome integrity and gene expression

(2010) Katherine M. Feeney et al.   BIOCHEMICAL JOURNAL

Deficiencies in the Fanconi Anemia DNA Damage Response Pathway Increase Sensitivity to HPV-Associated Head and Neck Cancer

(2010) J. W. Park et al.   CANCER RESEARCH

Expanded roles of the Fanconi anemia pathway in preserving genomic stability

(2010) Y. Kee et al.   GENES & DEVELOPMENT

Hepatitis C Virus Inhibits DNA Damage Repair through Reactive Oxygen and Nitrogen Species and by Interfering with the ATM-NBS1/Mre11/Rad50 DNA Repair Pathway in Monocytes and Hepatocytes

(2010) K. Machida et al.   JOURNAL OF IMMUNOLOGY

Multiple DNA Damage Signaling and Repair Pathways Deregulated by Simian Virus 40 Large T Antigen

(2010) S. Boichuk et al.   JOURNAL OF VIROLOGY

Destabilization of TIP60 by Human Papillomavirus E6 Results in Attenuation of TIP60-Dependent Transcriptional Regulation and Apoptotic Pathway

(2010) Sudhakar Jha et al.   MOLECULAR CELL

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments

(2010) Hans-Ulrich Bernard et al.   VIROLOGY

How the Fanconi Anemia Pathway Guards the Genome

(2009) George-Lucian Moldovan et al.   Annual Review of Genetics

Robust production and passaging of infectious HPV in squamous epithelium of primary human keratinocytes

(2009) H.-K. Wang et al.   GENES & DEVELOPMENT

The initial steps leading to papillomavirus infection occur on the basement membrane prior to cell surface binding

(2009) R. C. Kines et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

(2009) S. M. H. Sy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of Genomic Instability in Cells Infected with the High-Risk Human Papillomaviruses

(2009) Meelis Kadaja et al.   PLoS Pathogens

Human Papillomaviruses Activate the ATM DNA Damage Pathway for Viral Genome Amplification upon Differentiation

(2009) Cary A. Moody et al.   PLoS Pathogens

Role of Heparan Sulfate in Attachment to and Infection of the Murine Female Genital Tract by Human Papillomavirus

(2008) K. M. Johnson et al.   JOURNAL OF VIROLOGY

Coordinate regulation of Fanconi anemia gene expression occurs through the Rb/E2F pathway

(2008) E E Hoskins et al.   ONCOGENE

Fanconi anemia deficiency stimulates HPV-associated hyperplastic growth in organotypic epithelial raft culture

(2008) E E Hoskins et al.   ONCOGENE