Adenoviral Vectors Armed with Cell Fusion-Inducing Proteins as Anti-Cancer Agents

Expression of the fusogenic p14 FAST protein from a replication-defective adenovirus vector does not provide a therapeutic benefit in an immunocompetent mouse model of cancer

(2016) C M Wong et al.   CANCER GENE THERAPY

Epithelial Junction Opener Improves Oncolytic Adenovirus Therapy in Mouse Tumor Models

(2016) Roma Yumul et al.   HUMAN GENE THERAPY

Measles Virus Fusion Protein: Structure, Function and Inhibition

(2016) Philippe Plattet et al.   Viruses-Basel

Adenovirus-Mediated Expression of the p14 Fusion-Associated Small Transmembrane Protein Promotes Cancer Cell Fusion and Apoptosis In Vitro but Does Not Provide Therapeutic Efficacy in a Xenograft Mouse Model of Cancer

(2016) Carmen M. Wong et al.   PLoS One

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Talimogene Laherparepvec: First Global Approval

(2015) Sarah L. Greig   DRUGS

The history and future of targeting cyclin-dependent kinases in cancer therapy

(2015) Uzma Asghar et al.   NATURE REVIEWS DRUG DISCOVERY

The Adenovirus Genome Contributes to the Structural Stability of the Virion

(2014) Bratati Saha et al.   Viruses-Basel

Relevance of historical therapeutic approaches to the contemporary treatment of pediatric solid tumors

(2013) Daniel M. Green et al.   PEDIATRIC BLOOD & CANCER

Prostate Cancer-Specific and Potent Antitumor Effect of a DD3-Controlled Oncolytic Virus Harboring the PTEN Gene

(2012) Miao Ding et al.   PLoS One

GALV expression enhances the therapeutic efficacy of an oncolytic adenovirus by inducing cell fusion and enhancing virus distribution

(2011) S Guedan et al.   GENE THERAPY

Strategies to Enhance Viral Penetration of Solid Tumors

(2011) Elspeth Smith et al.   HUMAN GENE THERAPY

Chromatin structure of adenovirus DNA throughout infection

(2011) A. N. Giberson et al.   NUCLEIC ACIDS RESEARCH

Use of Cre/loxP recombination to swap cell binding motifs on the adenoviral capsid protein IX

(2011) Kathy L. Poulin et al.   VIROLOGY

Retargeting of Adenovirus Vectors through Genetic Fusion of a Single-Chain or Single-Domain Antibody to Capsid Protein IX

(2010) K. L. Poulin et al.   JOURNAL OF VIROLOGY

Synergistic Interaction Between Oncolytic Viruses Augments Tumor Killing

(2010) Fabrice Le Boeuf et al.   MOLECULAR THERAPY

Hyaluronidase Expression by an Oncolytic Adenovirus Enhances Its Intratumoral Spread and Suppresses Tumor Growth

(2010) Sonia Guedan et al.   MOLECULAR THERAPY

Active Adenoviral Vascular Penetration by Targeted Formation of Heterocellular Endothelial–epithelial Syncytia

(2010) Hannah H Chen et al.   MOLECULAR THERAPY

Phase II Clinical Trial of a Granulocyte-Macrophage Colony-Stimulating Factor–Encoding, Second-Generation Oncolytic Herpesvirus in Patients With Unresectable Metastatic Melanoma

(2009) Neil N. Senzer et al.   JOURNAL OF CLINICAL ONCOLOGY

Adenovirus Virion Stability and the Viral Genome: Size Matters

(2009) Michael A Kennedy et al.   MOLECULAR THERAPY

International epidemiology of human pre-existing adenovirus (Ad) type-5, type-6, type-26 and type-36 neutralizing antibodies: Correlates of high Ad5 titers and implications for potential HIV vaccine trials

(2009) T. Christopher Mast et al.   VACCINE

Inhibition of NF-κB in fusogenic membrane glycoprotein causing HL-60 cell death: Implications for acute myeloid leukemia

(2008) Li Tan et al.   CANCER LETTERS

Syncytia formation affects the yield and cytotoxicity of an adenovirus expressing a fusogenic glycoprotein at a late stage of replication

(2008) S Guedan et al.   GENE THERAPY

Presence of the Adenovirus IVa2 Protein at a Single Vertex of the Mature Virion

(2008) J. B. Christensen et al.   JOURNAL OF VIROLOGY

The p14 FAST Protein of Reptilian Reovirus Increases Vesicular Stomatitis Virus Neuropathogenesis

(2008) C. W. Brown et al.   JOURNAL OF VIROLOGY

DNA Genome Size Affects the Stability of the Adenovirus Virion

(2008) A. C. Smith et al.   JOURNAL OF VIROLOGY

Mechanics of membrane fusion

(2008) Leonid V Chernomordik et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Evaluation of Twenty-One Human Adenovirus Types and One Infectivity-Enhanced Adenovirus for the Treatment of Malignant Melanoma

(2007) Dennis Hoffmann et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY