PERV inactivation is necessary to guarantee absence of pig-to-patient PERVs transmission in xenotransplantation

Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9

(2017) Dong Niu et al.   SCIENCE

A comprehensive microbiological safety approach for agarose encapsulated porcine islets intended for clinical trials

(2016) Lawrence S. Gazda et al.   XENOTRANSPLANTATION

Genome-wide inactivation of porcine endogenous retroviruses (PERVs)

(2015) L. Yang et al.   SCIENCE

Elimination of porcine endogenous retroviruses from pig cells

(2015) Joachim Denner   XENOTRANSPLANTATION

Porcine endogenous retrovirus infection of human peripheral blood mononuclear cells

(2014) Joachim Denner   XENOTRANSPLANTATION

Microbiological safety of the first clinical pig islet xenotransplantation trial in New Zealand

(2014) Shaun Wynyard et al.   XENOTRANSPLANTATION

Long-term effects of PERV-specific RNA interference in transgenic pigs

(2012) Marwan Semaan et al.   XENOTRANSPLANTATION

High level expression of the anti-retroviral protein APOBEC3G is induced by influenza A virus but does not confer antiviral activity

(2009) Eva-K Pauli et al.   Retrovirology

Recombinant porcine endogenous retroviruses (PERV-A/C): a new risk for xenotransplantation?

(2008) Joachim Denner   ARCHIVES OF VIROLOGY