Polychlorinated biphenyls disrupt hepatic epidermal growth factor receptor signaling

Observation of hepatotoxicity during long-term gefitinib administration in patients with non-small-cell lung cancer

(2016) Jingjing Wang et al.   ANTI-CANCER DRUGS

Tipping the Balance: Hepatotoxicity and the 4 Apical Key Events of Hepatic Steatosis

(2016) Michelle M. Angrish et al.   TOXICOLOGICAL SCIENCES

The Roles of mTOR Complexes in Lipid Metabolism

(2015) Alexandre Caron et al.   Annual Review of Nutrition

EGFR Signaling in Liver Diseases

(2015) Karin Komposch et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fish Oil Contaminated with Persistent Organic Pollutants Reduces Antioxidant Capacity and Induces Oxidative Stress without Affecting Its Capacity to Lower Lipid Concentrations and Systemic Inflammation in Rats

(2015) Mee Young Hong et al.   JOURNAL OF NUTRITION

Polychlorinated Biphenyl-Xenobiotic Nuclear Receptor Interactions Regulate Energy Metabolism, Behavior, and Inflammation in Non-alcoholic-Steatohepatitis

(2015) Banrida Wahlang et al.   TOXICOLOGICAL SCIENCES

Potential effects of polychlorinated biphenyls (PCBs) and selected organochlorine pesticides (OCPs) on immune cells and blood biochemistry measures: a cross-sectional assessment of the NHANES 2003-2004 data

(2015) Berrin Serdar et al.   Environmental Health

Biomarkers Linking PCB Exposure and Obesity.

(2014) Somiranjan Ghosh et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Human  -Cell Proliferation and Intracellular Signaling Part 2: Still Driving in the Dark Without a Road Map

(2014) E. Bernal-Mizrachi et al.   DIABETES

GH Administration Rescues Fatty Liver Regeneration Impairment by Restoring GH/EGFR Pathway Deficiency

(2014) A. Collin de l'Hortet et al.   ENDOCRINOLOGY

Persistent organic pollutants and liver dysfunction biomarkers in a population-based human sample of men and women

(2014) Jitender Kumar et al.   ENVIRONMENTAL RESEARCH

Human Receptor Activation by Aroclor 1260, a Polychlorinated Biphenyl Mixture

(2014) Banrida Wahlang et al.   TOXICOLOGICAL SCIENCES

Evaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver disease

(2014) Banrida Wahlang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Coactivation of the PI3K/Akt and ERK signaling pathways in PCB153-induced NF-κB activation and caspase inhibition

(2014) Changjiang Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Phosphorylation of sterol regulatory element-binding protein (SREBP)-1c by p38 kinases, ERK and JNK influences lipid metabolism and the secretome of human liver cell line HepG2

(2014) Birgit Knebel et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Associations of organochlorine pesticides and polychlorinated biphenyls in visceral vs. subcutaneous adipose tissue with type 2 diabetes and insulin resistance

(2013) Ki-Su Kim et al.   CHEMOSPHERE

Evaluation of the Association between Persistent Organic Pollutants (POPs) and Diabetes in Epidemiological Studies: A National Toxicology Program Workshop Review

(2013) Kyla W. Taylor et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Multiple classes of environmental chemicals are associated with liver disease: NHANES 2003–2004

(2013) Krista L. Yorita Christensen et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Phenobarbital Indirectly Activates the Constitutive Active Androstane Receptor (CAR) by Inhibition of Epidermal Growth Factor Receptor Signaling

(2013) S. Mutoh et al.   Science Signaling

Polychlorinated Biphenyl (PCB) Exposure and Diabetes: Results from the Anniston Community Health Survey

(2012) Allen E. Silverstone et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Mortality after exposure to polychlorinated biphenyls and dibenzofurans: 30 years after the “Yucheng Accident”

(2012) Ming-Chieh Li et al.   ENVIRONMENTAL RESEARCH

Non-coplanar polychlorinated biphenyls (PCBs) are direct agonists for the human pregnane-X receptor and constitutive androstane receptor, and activate target gene expression in a tissue-specific manner

(2012) Fadheela Al-Salman et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inflammation-associated interleukin-6/signal transducer and activator of transcription 3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in interleukin-10-deficient mice

(2011) Andrew M. Miller et al.   HEPATOLOGY

Intrinsic Human Elimination Half-Lives of Polychlorinated Biphenyls Derived from the Temporal Evolution of Cross-Sectional Biomonitoring Data from the United Kingdom

(2010) Roland Ritter et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Polychlorinated Biphenyls, Lead, and Mercury Are Associated with Liver Disease in American Adults: NHANES 2003–2004

(2010) Matt Cave et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Perfluorinated Compounds, Polychlorinated Biphenyls, and Organochlorine Pesticide Contamination in Composite Food Samples from Dallas, Texas, USA

(2010) Arnold Schecter et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Blood pressure and hypertension in relation to levels of serum polychlorinated biphenyls in residents of Anniston, Alabama

(2010) Alexey Goncharov et al.   JOURNAL OF HYPERTENSION

An Environment-Wide Association Study (EWAS) on Type 2 Diabetes Mellitus

(2010) Chirag J. Patel et al.   PLoS One

The Constitutive Androstane Receptor Is an Anti-obesity Nuclear Receptor That Improves Insulin Sensitivity

(2009) Jie Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EGF receptor in pancreatic β-cell mass regulation

(2008) Päivi Miettinen et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Genetic variants in STAT3 are associated with nonalcoholic fatty liver disease

(2008) Silvia Sookoian et al.   CYTOKINE

Increased Risk of Diabetes and Polychlorinated Biphenyls and Dioxins: A 24-year follow-up study of the Yucheng cohort

(2008) S.-L. Wang et al.   DIABETES CARE