Recombinant adeno-associated virus carrying thymosin β4 suppresses experimental colitis in mice

Long-Term Effect of Gene Therapy on Leber’s Congenital Amaurosis

(2015) James W.B. Bainbridge et al.   NEW ENGLAND JOURNAL OF MEDICINE

Extracellular Vesicles Derived from Bone Marrow Mesenchymal Stem Cells Protect against Experimental Colitis via Attenuating Colon Inflammation, Oxidative Stress and Apoptosis

(2015) Jia Yang et al.   PLoS One

Thymosin-β4 prevents cardiac rupture and improves cardiac function in mice with myocardial infarction

(2014) Hongmei Peng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

In vivo growth suppression of CT-26 mouse colorectal cancer cells by adenovirus-expressed small hairpin RNA specifically targeting thymosin beta-4 mRNA

(2014) T-C Chao et al.   CANCER GENE THERAPY

Thymosin Beta-4 Knockdown in IEC-6 Normal Intestinal Epithelial Cells Induces DNA Re-replication Via Downregulating Emi1

(2014) Ta-Chung Chao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Thymosin β4administration enhances fracture healing in mice

(2014) Rhys D. Brady et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

A dose–response study of thymosin β4 for the treatment of acute stroke

(2014) D.C. Morris et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Beneficial effects of thymosin β4 on spinal cord injury in the rat

(2014) Peng Cheng et al.   NEUROPHARMACOLOGY

Long-Term Safety and Efficacy of Factor IX Gene Therapy in Hemophilia B

(2014) Amit C. Nathwani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Thymosin β4-sulfoxide attenuates inflammatory cell infiltration and promotes cardiac wound healing

(2013) Mark A. Evans et al.   Nature Communications

Thymosin β4 is rapidly internalized by cells and does not induce intracellular Ca2+elevation

(2012) Czeslaw S. Cierniewski et al.   Annals of the New York Academy of Sciences

Thymosin β4 protects C57BL/6 mice from bleomycin-induced damage in the lung

(2012) Enrico Conte et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Adenovirus-mediated hepatocarcinoma-intestine-pancreas/pancreatitis-associated protein suppresses dextran sulfate sodium-induced acute ulcerative colitis in rats

(2012) Yifei Lv et al.   INFLAMMATORY BOWEL DISEASES

IL-10— and IL-20—Expressing Epithelial and Inflammatory Cells are Increased in Patients with Ulcerative Colitis

(2012) Gabriela Fonseca-Camarillo et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Inflammatory gene expression profiles in Crohn's disease and ulcerative colitis: A comparative analysis using a reverse transcriptase multiplex ligation-dependent probe amplification protocol

(2012) Serban Gologan et al.   Journal of Crohns & Colitis

Intracolonically administered adeno-associated virus-bone morphogenetic protein-7 ameliorates dextran sulphate sodium-induced acute colitis in rats

(2012) Zhiming Hao et al.   JOURNAL OF GENE MEDICINE

Thymosin Beta 4 Protects Cardiomyocytes from Oxidative Stress by Targeting Anti-Oxidative Enzymes and Anti-Apoptotic Genes

(2012) Chuanyu Wei et al.   PLoS One

The effect of IL-10 genetic variation and interleukin 10 serum levels on Crohn's disease susceptibility in a New Zealand population

(2011) Alice H. Wang et al.   HUMAN IMMUNOLOGY

Thymosin Beta 4 Prevents Oxidative Stress by Targeting Antioxidant and Anti-Apoptotic Genes in Cardiac Fibroblasts

(2011) Sandeep Kumar et al.   PLoS One

A Phase 2 Study to Evaluate the Safety and Immunogenicity of a Recombinant HIV Type 1 Vaccine Based on Adeno-Associated Virus

(2010) Eftyhia Vardas et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Thymosin β4 and its posttranslational modifications

(2010) E. Hannappel   Annals of the New York Academy of Sciences

Thymosin β4: structure, function, and biological properties supporting current and future clinical applications

(2010) David Crockford et al.   Annals of the New York Academy of Sciences

The polymorphism rs3024505 proximal to IL-10 is associated with risk of ulcerative colitis and Crohns disease in a Danish case-control study

(2010) Vibeke Andersen et al.   BMC Medical Genetics

Apoptosis resistance of mucosal lymphocytes and IL-10 deficiency in patients with steroid-refractory Crohnʼs disease

(2010) Rebeca Santaolalla et al.   INFLAMMATORY BOWEL DISEASES

Different Thymosin Beta 4 Immunoreactivity in Foetal and Adult Gastrointestinal Tract

(2010) Sonia Nemolato et al.   PLoS One

Thymosin β4 Expression in Human Tissues and in Tumors Using Tissue Microarrays

(2010) Jin-Ok Jo et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Proinflammatory cytokines and IL-10 in inflammatory bowel disease and colorectal cancer patients

(2009) Andrzej Szkaradkiewicz et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Defective IL-10 production in severe phenotypes of Crohn's disease

(2009) Ismael Correa et al.   JOURNAL OF LEUKOCYTE BIOLOGY

High Levels of Proinflammatory Cytokines, but Not Markers of Tissue Injury, in Unaffected Intestinal Areas from Patients with IBD

(2009) Alberto J. León et al.   MEDIATORS OF INFLAMMATION

Neurological functional recovery after thymosin beta4 treatment in mice with experimental auto encephalomyelitis

(2009) J. Zhang et al.   NEUROSCIENCE

The β-thymosins: Intracellular and extracellular activities of a versatile actin binding protein family

(2009) Hans Georg Mannherz et al.   CELL MOTILITY AND THE CYTOSKELETON

Thymosin beta-4 upregulates anti-oxidative enzymes and protects human cornea epithelial cells against oxidative damage

(2008) J H-C Ho et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Cytokine network in rectal mucosa in perianal Crohnʼs disease: Relations with inflammatory parameters and need for surgery

(2008) Cesare Ruffolo et al.   INFLAMMATORY BOWEL DISEASES