Gastrointestinal neuroendocrine peptides/amines in inflammatory bowel disease

Abnormal differentiation of stem cells into enteroendocrine cells in rats with DSS-induced colitis

(2017) Magdy El-Salhy et al.   Molecular Medicine Reports

The pro-inflammatory cytokines IFN /TNF  increase chromogranin A-positive neuroendocrine cells in the colonic epithelium

(2016) J. A. Hernandez-Trejo et al.   BIOCHEMICAL JOURNAL

Neuropeptide substance P and the immune response

(2016) Alireza Mashaghi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Treatment with novel AP-1 and NF-κB inhibitors restores the colonic endocrine cells to normal levels in rats with DSS-induced colitis

(2016) MAGDY EL-SALHY et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Enteroendocrine cells, stem cells and differentiation progenitors in rats with TNBS-induced colitis

(2016) Magdy El-Salhy et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

VIP impairs acquisition of the macrophage proinflammatory polarization profile

(2016) Mar Carrión et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Effects of AP-1 and NF-κB inhibitors on colonic endocrine cells in rats with TNBS-induced colitis

(2016) Magdy El-Salhy et al.   Molecular Medicine Reports

Abnormalities in endocrine and immune cells are correlated in dextran-sulfate-sodium-induced colitis in rats

(2016) Magdy El-Salhy et al.   Molecular Medicine Reports

Changes in enteroendocrine and immune cells following colitis induction by TNBS in rats

(2016) Magdy El-Salhy et al.   Molecular Medicine Reports

Vasoactive intestinal peptide dampens formyl-peptide-induced ROS production and inflammation by targeting a MAPK-p47phox phosphorylation pathway in monocytes

(2016) P Chedid et al.   Mucosal Immunology

The role of the neuropeptide Y (NPY) family in the pathophysiology of inflammatory bowel disease (IBD)

(2016) Magdy El-Salhy et al.   NEUROPEPTIDES

Chromogranin A and other enteroendocrine markers in inflammatory bowel disease

(2016) Sara Massironi et al.   NEUROPEPTIDES

Enteric Neuronal Regulation of Intestinal Inflammation

(2016) Kara Gross Margolis et al.   TRENDS IN NEUROSCIENCES

The possible role of gastrointestinal endocrine cells in the pathophysiology of irritable bowel syndrome

(2016) Magdy El-Salhy et al.   Expert Review of Gastroenterology & Hepatology

Prevalence of Inflammatory Bowel Disease Among Adults Aged ≥18 Years — United States, 2015

(2016) James M. Dahlhamer et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Familial aggregation in inflammatory bowel disease: Is it genes or environment?

(2016) Tiago Nunes   WORLD JOURNAL OF GASTROENTEROLOGY

The intestinal immunoendocrine axis: novel cross-talk between enteroendocrine cells and the immune system during infection and inflammatory disease: Figure 1

(2015) John J Worthington   BIOCHEMICAL SOCIETY TRANSACTIONS

Vasoactive intestinal peptide reduces the inflammatory profile in mice infected with Trypanosoma cruzi

(2015) Pulchéria Maria Silva Higyno et al.   EXPERIMENTAL PARASITOLOGY

Vasoactive intestinal peptide suppresses macrophage-mediated inflammation by downregulating interleukin-17A expression via PKA- and PKC-dependent pathways

(2015) Wen-Zhuo Ran et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Colitis-induced neuroplasticity disrupts motility in the inflamed and post-inflamed colon

(2015) Gary M. Mawe   JOURNAL OF CLINICAL INVESTIGATION

Neuroepithelial circuit formed by innervation of sensory enteroendocrine cells

(2015) Diego V. Bohórquez et al.   JOURNAL OF CLINICAL INVESTIGATION

The Role of Neuropeptides in Mouse Models of Colitis

(2015) David Padua et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Immunomodulatory effect of ghrelin in the intestinal mucosa

(2015) N. Eissa et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The neuropeptide vasoactive intestinal peptide: direct effects on immune cells and involvement in inflammatory and autoimmune diseases

(2014) D. Ganea et al.   Acta Physiologica

The role of serotonin and its receptors in activation of immune responses and inflammation

(2014) M. S. Shajib et al.   Acta Physiologica

Physiological underpinnings of irritable bowel syndrome: neurohormonal mechanisms

(2014) Michael Camilleri   JOURNAL OF PHYSIOLOGY-LONDON

An Enteroendocrine Cell – Enteric Glia Connection Revealed by 3D Electron Microscopy

(2014) Diego V. Bohórquez et al.   PLoS One

Gut microbiota and GLP-1

(2014) Amandine Everard et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Chromogranin A as a biomarker of disease activity and biologic therapy in inflammatory bowel disease: a prospective observational study

(2014) Athanasios Zissimopoulos et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Is irritable bowel syndrome an organic disorder?

(2014) Magdy El-Salhy   WORLD JOURNAL OF GASTROENTEROLOGY

Biological function and clinical relevance of chromogranin A and derived peptides

(2014) Maria Angela D'amico et al.   Endocrine Connections

Review article: the role of anti-TNF in the management of ulcerative colitis - past, present and future

(2013) S. Danese et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Fiber and Functional Gastrointestinal Disorders

(2013) Shanti Eswaran et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Emerging neuropeptide targets in inflammation: NPY and VIP

(2013) Bindu Chandrasekharan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Enteroendocrine cell types revisited

(2013) Maja S Engelstoft et al.   CURRENT OPINION IN PHARMACOLOGY

Gut microbiota, enteroendocrine functions and metabolism

(2013) Patrice D Cani et al.   CURRENT OPINION IN PHARMACOLOGY

Co-localisation and secretion of glucagon-like peptide 1 and peptide YY from primary cultured human L cells

(2013) A. M. Habib et al.   DIABETOLOGIA

The Risks and Benefits of Early Immunosuppression and Biological Therapy

(2013) Bruce E. Sands   DIGESTIVE DISEASES

Selective inhibition of mucosal serotonin as treatment for IBD?

(2013) Alon D Levin et al.   GUT

Role of Ghrelin in the Pathophysiology of Gastrointestinal Disease

(2013) Cynthia K. Cheung et al.   Gut and Liver

Increased Fecal Levels of Chromogranin A, Chromogranin B, and Secretoneurin in Collagenous Colitis

(2013) Michael Wagner et al.   INFLAMMATION

Adherence to Anti-TNF Therapy in Inflammatory Bowel Diseases

(2013) Anthony Lopez et al.   INFLAMMATORY BOWEL DISEASES

Inflammatory Bowel Disease Prevalence by Age, Gender, Race, and Geographic Location in the U.S. Military Health Care Population

(2013) John D. Betteridge et al.   INFLAMMATORY BOWEL DISEASES

Clinical presentation, diagnosis, pathogenesis and treatment options for lymphocytic colitis (Review)

(2013) MAGDY EL-SALHY et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Fecal chromogranins and secretogranins are increased in patients with ulcerative colitis but are not associated with disease activity

(2013) Hans Strid et al.   Journal of Crohns & Colitis

Targeted Inhibition of Serotonin Type 7 (5-HT7) Receptor Function Modulates Immune Responses and Reduces the Severity of Intestinal Inflammation

(2013) J. J. Kim et al.   JOURNAL OF IMMUNOLOGY

Oxidative stress disrupts purinergic neuromuscular transmission in the inflamed colon

(2013) Jane A. Roberts et al.   JOURNAL OF PHYSIOLOGY-LONDON

Interleukin 13 and Serotonin: Linking the Immune and Endocrine Systems in Murine Models of Intestinal Inflammation

(2013) Md. Sharif Shajib et al.   PLoS One

Glucocorticosteroids in the treatment of inflammatory bowel disease and approaches to minimizing systemic activity

(2013) Cosimo Prantera et al.   Therapeutic Advances in Gastroenterology

A Dialogue between the Immune System and Brain, Spoken in the Language of Serotonin

(2012) Nicole L. Baganz et al.   ACS Chemical Neuroscience

Systematic review: are lymphocytic colitis and collagenous colitis two subtypes of the same disease - microscopic colitis?

(2012) M. A. Rasmussen et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Irritable Bowel Syndrome: Methods, Mechanisms, and Pathophysiology. The confluence of increased permeability, inflammation, and pain in irritable bowel syndrome

(2012) Michael Camilleri et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells

(2012) Mary A. Zimmerman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Identifying the Stem Cell of the Intestinal Crypt: Strategies and Pitfalls

(2012) Nick Barker et al.   Cell Stem Cell

The roles of purinergic signaling during gastrointestinal inflammation

(2012) Jane A Roberts et al.   CURRENT OPINION IN PHARMACOLOGY

Chromogranin A Cell Density as a Diagnostic Marker for Lymphocytic Colitis

(2012) Magdy El-Salhy et al.   DIGESTIVE DISEASES AND SCIENCES

Impact of 5-HT3 receptor antagonists on peripheral and central diseases

(2012) Gohar Fakhfouri et al.   DRUG DISCOVERY TODAY

A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin

(2012) Kristoffer L. Egerod et al.   ENDOCRINOLOGY

Overlap of Endocrine Hormone Expression in the Mouse Intestine Revealed by Transcriptional Profiling and Flow Cytometry

(2012) Abdella M. Habib et al.   ENDOCRINOLOGY

The role of peptide YY in gastrointestinal diseases and disorders

(2012) MAGDY EL-SALHY et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Viscous versus nonviscous soluble fiber supplements: Mechanisms and evidence for fiber-specific health benefits

(2012) Robynne Chutkan et al.   Journal of the American Academy of Nurse Practitioners

Diffuse Endocrine System, Neuroendocrine Tumors and Immunity: What’s New?

(2012) Pietro Ameri et al.   NEUROENDOCRINOLOGY

Peripheral Mechanisms in Irritable Bowel Syndrome

(2012) Michael Camilleri   NEW ENGLAND JOURNAL OF MEDICINE

Differential Effects of Two Fermentable Carbohydrates on Central Appetite Regulation and Body Composition

(2012) Tulika Arora et al.   PLoS One

High densities of serotonin and peptide YY cells in the colon of patients with lymphocytic colitis

(2012) Magdy El-Salhy   WORLD JOURNAL OF GASTROENTEROLOGY

Review article: infliximab for Crohn’s disease treatment - shifting therapeutic strategies after 10 years of clinical experience

(2011) S. Danese et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Glucose sensing by gut endocrine cells and activation of the vagal afferent pathway is impaired in a rodent model of type 2 diabetes mellitus

(2011) Jennifer Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Sex-dependent control of murine emotional-affective behaviour in health and colitis by peptide YY and neuropeptide Y

(2011) Evelin Painsipp et al.   BRITISH JOURNAL OF PHARMACOLOGY

5-HT and the immune system

(2011) Gerard P Ahern   CURRENT OPINION IN PHARMACOLOGY

Epidemiology and Natural History of Inflammatory Bowel Diseases

(2011) Jacques Cosnes et al.   GASTROENTEROLOGY

Experimental Inflammatory Bowel Disease: Insights into the Host-Microbiota Dialog

(2011) Maya Saleh et al.   IMMUNITY

Classification and functions of enteroendocrine cells of the lower gastrointestinal tract

(2011) Ashok R. Gunawardene et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

High chromogranin A cell density in the colon of patients with lymphocytic colitis

(2011) M. El-Salhy   Molecular Medicine Reports

Parietal cell activation by arborization of ECL cell cytoplasmic projections is likely the mechanism for histamine induced secretion of hydrochloric acid

(2011) Björn I. Gustafsson et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Enteroendocrine cells: a site of ‘taste’ in gastrointestinal chemosensing

(2011) Catia Sternini et al.   Current Opinion in Endocrinology Diabetes and Obesity

Gut hormones: emerging role in immune activation and inflammation

(2010) W. I. Khan et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Pathology of Gastrointestinal Disorders

(2010) Guido Rindi et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Molecular mechanisms underlying nutrient-stimulated incretin secretion

(2010) Helen E. Parker et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Short-Chain Fatty Acids Regulate the Enteric Neurons and Control Gastrointestinal Motility in Rats

(2010) Rodolphe Soret et al.   GASTROENTEROLOGY

Granisetron ameliorates acetic acid-induced colitis in rats

(2010) Gohar Fakhfouri et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Amelioration of dextran sulfate sodium-induced colitis by neuropeptide Y antisense oligodeoxynucleotide

(2010) Xue Hua Pang et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Characterization of basal pseudopod-like processes in ileal and colonic PYY cells

(2010) Diego V. Bohórquez et al.   JOURNAL OF MOLECULAR HISTOLOGY

Purinergic neuromuscular transmission is selectively attenuated in ulcerated regions of inflamed guinea pig distal colon

(2010) Derek S. Strong et al.   JOURNAL OF PHYSIOLOGY-LONDON

Chromogranin A as a possible tool in the diagnosis of irritable bowel syndrome

(2010) Magdy El-Salhy et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Serotonin release and uptake in the gastrointestinal tract

(2009) Paul P. Bertrand et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Neuropeptides and inflammatory bowel disease

(2009) Kara Gross Margolis et al.   CURRENT OPINION IN GASTROENTEROLOGY

Anti-inflammatory effects of 5-HT3receptor antagonist, tropisetron on experimental colitis in rats

(2009) K. Mousavizadeh et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

New and emerging biologics in the treatment of inflammatory bowel disease: quo vadis?

(2009) S. Danese et al.   GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE

Serotonin Has a Key Role in Pathogenesis of Experimental Colitis

(2009) Jean–Eric Ghia et al.   GASTROENTEROLOGY

Elevated Serum Chromogranin a in Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD): A Shared Model for Pathogenesis?

(2009) Reena Sidhu et al.   INFLAMMATORY BOWEL DISEASES

Chromogranin A Promotes Peptide Hormone Sorting to Mobile Granules in Constitutively and Regulated Secreting Cells

(2009) Maité Montero-Hadjadje et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammatory bowel disease: A survey of the epidemiology in Asia

(2009) KL GOH et al.   Journal of Digestive Diseases

Gut endocrine cell development

(2009) Catherine Lee May et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Impaired defense mechanism against inflammation, hyperalgesia, and airway hyperreactivity in somatostatin 4 receptor gene-deleted mice

(2009) Z. Helyes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Granin-derived peptides as diagnostic and prognostic markers for endocrine tumors

(2009) J. Michael Conlon   REGULATORY PEPTIDES

Modulation of granulocyte functions by peptide YY in the rat: Age-related differences in Y receptors expression and plasma dipeptidyl peptidase 4 activity

(2009) Mirjana Dimitrijević et al.   REGULATORY PEPTIDES

Regulatory peptides from chromogranin A and secretogranin II: Putative modulators of cells and tissues involved in inflammatory conditions

(2009) Karen B. Helle   REGULATORY PEPTIDES

The antimicrobial peptides derived from chromogranin/secretogranin family, new actors of innate immunity

(2009) Peiman Shooshtarizadeh et al.   REGULATORY PEPTIDES

Stimulation of CCL2 (MCP-1) and CCL2 mRNA by substance P in LAD2 human mast cells

(2009) Maria Luisa Castellani et al.   Translational Research

The cornucopia of intestinal chemosensory transduction

(2009) Paul Bertrand   Frontiers in Neuroscience

Neuropeptides Rescue Mice from Lethal Sepsis by Down-regulating Secretion of the Late-Acting Inflammatory Mediator High Mobility Group Box 1

(2008) Alejo Chorny et al.   AMERICAN JOURNAL OF PATHOLOGY

Substance P enhances NF-κB transactivation and chemokine response in murine macrophages via ERK1/2 and p38 MAPK signaling pathways

(2008) Jia Sun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Ciliated epithelial cell lifespan in the mouse trachea and lung

(2008) Emma L. Rawlins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Monocyte migration: A novel effect and signaling pathways of catestatin

(2008) Margot Egger et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The intestinal stem cell

(2008) N. Barker et al.   GENES & DEVELOPMENT

Phenotypical and functional study of ghrelin and its receptor in the pathogenesis of Crohnʼs disease

(2008) Shuhei Hosomi et al.   INFLAMMATORY BOWEL DISEASES

Plasma chromogranin a in patients with inflammatory bowel disease

(2008) Valentina Sciola et al.   INFLAMMATORY BOWEL DISEASES

Small intestinal stem cell markers

(2008) Robert K. Montgomery et al.   JOURNAL OF ANATOMY

Serotonin and GI clinical disorders

(2008) Robin Spiller   NEUROPHARMACOLOGY

Targeted Deletion of Neuropeptide Y (NPY) Modulates Experimental Colitis

(2008) Bindu Chandrasekharan et al.   PLoS One

Release of regulatory gut peptides somatostatin, neurotensin and vasoactive intestinal peptide by acid and hyperosmolal solutions in the intestine in conscious rats

(2008) T. Rudholm et al.   REGULATORY PEPTIDES

Exogenous ghrelin modulates release of pro-inflammatory and anti-inflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways

(2008) Talat Waseem et al.   SURGERY

Review: Enteroendocrine cells: Neglected players in gastrointestinal disorders?

(2008) Gordon W. Moran et al.   Therapeutic Advances in Gastroenterology

Morphological relationships between peptidergic nerve fibers and immunoglobulin A-producing lymphocytes in the mouse intestine

(2007) Maiko Shibata et al.   BRAIN BEHAVIOR AND IMMUNITY

Biological agents for ulcerative colitis: Hypes and hopes

(2007) Silvio Danese et al.   MEDICINAL RESEARCH REVIEWS