Article
Medicine, General & Internal
Oussama M. Wazni, Gopi Dandamudi, Nitesh Sood, Robert Hoyt, Jaret Tyler, Sarfraz Durrani, Mark Niebauer, Kevin Makati, Blair Halperin, Andre Gauri, Gustavo Morales, Mingyuan Shao, Jeffrey Cerkvenik, Rachelle E. Kaplon, Steven E. Nissen
Summary: In this multicenter trial, cryoballoon ablation as initial therapy was found to be superior to drug therapy in preventing atrial arrhythmia recurrence in patients with paroxysmal atrial fibrillation. Serious procedure-related adverse events were uncommon.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Medical Laboratory Technology
Rangrang Zhang, Weidong Jin, Minglei Han, Yonglan Hou
Summary: Atrial fibrillation (AF) is a common clinical arrhythmia associated with increased risk of death, stroke, and peripheral vascular embolism. Catheter ablation (CA) is an effective treatment, but a high recurrence rate remains a challenge. Identifying biomarkers for prediction of AF recurrence after CA is important for personalized treatment. Carbohydrate antigen 125 (CA-125) has been widely studied and may serve as a useful marker for AF.
CLINICA CHIMICA ACTA
(2023)
Article
Medicine, General & Internal
Jason G. Andrade, George A. Wells, Marc W. Deyell, Matthew Bennett, Vidal Essebag, Jean Champagne, Jean-Francois Roux, Derek Yung, Allan Skanes, Yaariv Khaykin, Carlos Morillo, Umjeet Jolly, Paul Novak, Evan Lockwood, Guy Amit, Paul Angaran, John Sapp, Stephan Wardell, Sandra Lauck, Laurent Macle, Atul Verma
Summary: In patients with symptomatic, paroxysmal atrial fibrillation, catheter cryoballoon ablation was associated with a significantly lower rate of atrial fibrillation recurrence compared to antiarrhythmic drug therapy. The ablation group also had better outcomes in terms of atrial tachyarrhythmia occurrence and atrial fibrillation burden.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Girish M. Nair, David H. Birnie, Pablo B. Nery, Calum J. Redpath, Jean-Francois Sarrazin, Jean-Francois Roux, Ratika Parkash, Martin Bernier, Laurence D. Sterns, John Sapp, Paul Novak, George Veenhuyzen, Carlos A. Morillo, Sheldon M. Singh, Mouhannad M. Sadek, Mehrdad Golian, Andres Klein, Marcio Sturmer, Vijay S. Chauhan, Paul Angaran, Martin S. Green, Jordan Bernick, George A. Wells, Vidal Essebag
Summary: In this study, an augmented double wide-area circumferential ablation (WACA) did not show superiority in preventing recurrent atrial arrhythmias compared to a standard single WACA in patients with paroxysmal AF. The additional ablation did not improve freedom from atrial arrhythmias or safety.
Article
Medicine, General & Internal
Rani Kronenberger, Ines Van Loo, Carlo de Asmundis, Maridi Aerts, Sandro Gelsomino, Vincent Umbrain, Gian-Battista Chierchia, Mark La Meir
Summary: In patients undergoing hybrid ablation, postoperative esophageal findings were studied to assess the risk of atrio-esophageal fistula. Novel preventive strategies were found to eliminate the potential risk of esophageal thermal lesions, highlighting the importance of comprehensive pre-operative screening in patients with preexisting esophageal disease.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Cardiac & Cardiovascular Systems
Lucas Boersma, Jason G. Andrade, Tim Betts, Mattias Duytschaever, Helmut Purerfellner, Francesco Santoro, Stylianos Tzeis, Atul Verma
Summary: Over the past 25 years, there has been a significant interest in developing new catheters and energy sources to optimize the durability and safety of ablation, as well as studying the mechanisms for atrial fibrillation and devising ablation strategies. Although pulmonary vein ablation has been the basis for every AF ablation, it has been recognized that this is not enough to cure all patients, especially those with non-paroxysmal AF.
Article
Cardiac & Cardiovascular Systems
Yuxia Miao, Min Xu, Ling Yang, Chunxu Zhang, Huannian Liu, Xiaoliang Shao
Summary: This study found a linear and positive association between P wave duration within 72 hours after radiofrequency ablation and the risk of atrial fibrillation recurrence in patients with early persistent atrial fibrillation. This association was consistent across different subgroups and there was no significant interaction.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Article
Medicine, General & Internal
Nassir F. Marrouche, Oussama Wazni, Christopher McGann, Tom Greene, J. Michael Dean, Lilas Dagher, Eugene Kholmovski, Moussa Mansour, Francis Marchlinski, David Wilber, Gerhard Hindricks, Christian Mahnkopf, Darryl Wells, Pierre Jais, Prashanthan Sanders, Johannes Brachmann, Jeroen J. Bax, Leonie Morrison-de Boer, Thomas Deneke, Hugh Calkins, Christian Sohns, Nazem Akoum
Summary: Among patients with persistent atrial fibrillation, MRI-guided fibrosis ablation in addition to PVI did not show significant reduction in atrial arrhythmia recurrence compared to PVI catheter ablation alone. The findings do not support the use of MRI-guided fibrosis ablation for the treatment of persistent AF.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2022)
Article
Medicine, General & Internal
Xinlu Wang, Zefeng Wang, Xiaohan Yan, Manyun Huang, Yongquan Wu
Summary: The study showed that catheter ablation can improve cognitive function in patients with atrial fibrillation better than drug therapy alone. There were no significant differences in cognitive function improvement between radiofrequency ablation and cryoballoon ablation, but both procedures showed significant improvement compared to drug therapy.
Article
Medicine, General & Internal
Yun Young Choi, Jaemin Shim, Yun Gi Kim, Kyongjin Min, Seung-Young Roh, Jin Seok Kim, Jong-Il Choi, Young-Hoon Kim
Summary: Adenosine-induced atrial fibrillation (AIAF) does not affect the long-term recurrence rate after pulmonary vein isolation (PVI). Additional ablation for the trigger site of AIAF does not improve clinical outcomes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Immunology
Dishiwen Liu, Yajia Li, Qingyan Zhao
Summary: Atrial fibrillation (AF) is a serious healthcare burden with high morbidity and complications. Catheter ablation, although curable, currently has a low long-term success rate. Inflammation and fibrosis play significant roles in AF progression, and the artificial inflammatory response caused by catheter ablation may impact long-term prognosis. This review focuses on the different types of inflammatory cell death induced by various ablation techniques, as well as the structural and electrical remodeling caused by inflammation and its association with AF recurrence after catheter ablation. Pulsed-field ablation shows promise as a revolutionary innovation with faster, safer, better tissue selectivity, and less inflammatory response.
JOURNAL OF INFLAMMATION RESEARCH
(2023)
Review
Cardiac & Cardiovascular Systems
Wei-Chieh Lee, Po-Jui Wu, Huang-Chung Chen, Hsiu-Yu Fang, Ping-Yen Liu, Mien-Cheng Chen
Summary: Elderly patients undergoing AF ablation have significantly higher rates of recurrent AF or ATA and complications compared to non-elderly patients, except for patients aged 75 years and older.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Ling You, Xiaohong Zhang, Jing Yang, Lianxia Wang, Yan Zhang, Ruiqin Xie
Summary: This study compared the long-term recurrence rates of paroxysmal atrial fibrillation treated by radiofrequency ablation, cryoablation, and three-dimensional guided cryoablation plus radiofrequency ablation, revealing no statistically significant difference among the three groups. The preoperative left atrial appendage emptying velocity and left atrial dimensions were found to be predictive factors for postoperative recurrence of atrial fibrillation.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Jason G. Andrade, Marc W. Deyell, Paul Khairy, Jean Champagne, Peter Leong-Sit, Paul Novak, Lawrence Sterns, Jean-Francois Roux, John Sapp, Richard Bennett, Matthew Bennett, Nathaniel Hawkins, Prashanthan Sanders, Laurent Macle
Summary: Catheter ablation using radiofrequency energy for paroxysmal AF can reduce the risk of progression to persistent AF.
EUROPEAN HEART JOURNAL
(2023)
Article
Nutrition & Dietetics
Youzheng Dong, Ting Huang, Zhenyu Zhai, Quanbin Dong, Zhen Xia, Zirong Xia, Jianhua Yu, Xinghua Jiang, Kui Hong, Yanqing Wu, Xiaoshu Cheng, Juxiang Li
Summary: In H-type hypertensive AF patients treated with first RFCA, folic acid supplementation is associated with a reduced risk of AF recurrence.
FRONTIERS IN NUTRITION
(2022)