Multifunctional nanoparticle composites: progress in the use of soft and hard nanoparticles for drug delivery and imaging

Alizarin Complexone Functionalized Mesoporous Silica Nanoparticles: A Smart System Integrating Glucose-Responsive Double-Drugs Release and Real-Time Monitoring Capabilities

(2016) Zhen Zou et al.   ACS Applied Materials & Interfaces

pH-Triggered Polypeptides Nanoparticles for Efficient BODIPY Imaging-Guided Near Infrared Photodynamic Therapy

(2016) Le Liu et al.   ACS Applied Materials & Interfaces

Co-Delivery of Cisplatin Prodrug and Chlorin e6 by Mesoporous Silica Nanoparticles for Chemo-Photodynamic Combination Therapy to Combat Drug Resistance

(2016) Wei Zhang et al.   ACS Applied Materials & Interfaces

Intracellularly Acid-Switchable Multifunctional Micelles for Combinational Photo/Chemotherapy of the Drug-Resistant Tumor

(2016) Tingting Wang et al.   ACS Nano

A theranostic micelleplex co-delivering SN-38 and VEGF siRNA for colorectal cancer therapy

(2016) Shin-Yu Lee et al.   BIOMATERIALS

pH-sensitive polymeric micelles formed by doxorubicin conjugated prodrugs for co-delivery of doxorubicin and paclitaxel

(2016) Yakun Ma et al.   CARBOHYDRATE POLYMERS

Carbon dots incorporated polymeric hydrogels as multifunctional platform for imaging and induction of apoptosis in lung cancer cells

(2016) Abhay Sachdev et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Folate receptor-targeted multimodal polymersomes for delivery of quantum dots and doxorubicin to breast adenocarcinoma: In vitro and in vivo evaluation

(2016) Mona Alibolandi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

PEGylated polyethylenimine-entrapped gold nanoparticles loaded with gadolinium for dual-mode CT/MR imaging applications

(2016) Benqing Zhou et al.   Nanomedicine

Optimization of anti-cancer drugs and a targeting molecule on multifunctional gold nanoparticles

(2016) Nahla Rizk et al.   NANOTECHNOLOGY

Meta-analysis of cellular toxicity for cadmium-containing quantum dots

(2016) Eunkeu Oh et al.   Nature Nanotechnology

Upconversion luminescence tracking of gene delivery via multifunctional nanocapsules

(2016) Xilin Bai et al.   TALANTA

One-pot aqueous synthesis of gadolinium doped CdTe quantum dots with dual imaging modalities

(2016) Chunli Jiang et al.   TALANTA

Facile synthesis of ternary CdMnS QD-based hollow nanospheres as fluorescent/magnetic probes for bioimaging

(2016) Bingxia Zhao et al.   Journal of Materials Chemistry B

Paramagnetic albumin decorated CuInS2/ZnS QDs for CD133+ glioma bimodal MR/fluorescence targeted imaging

(2016) Jing Zhang et al.   Journal of Materials Chemistry B

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Peptides for Specifically Targeting Nanoparticles to Cellular Organelles: Quo Vadis?

(2015) Lauren D. Field et al.   ACCOUNTS OF CHEMICAL RESEARCH

Dual-Responsive Polymer Coated Superparamagnetic Nanoparticle for Targeted Drug Delivery and Hyperthermia Treatment

(2015) Santanu Patra et al.   ACS Applied Materials & Interfaces

Facile Synthesis of Gd–Cu–In–S/ZnS Bimodal Quantum Dots with Optimized Properties for Tumor Targeted Fluorescence/MR In Vivo Imaging

(2015) Weitao Yang et al.   ACS Applied Materials & Interfaces

Structure-Invertible Nanoparticles for Triggered Co-Delivery of Nucleic Acids and Hydrophobic Drugs for Combination Cancer Therapy

(2015) Kai Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Core-Shell Upconversion Nanoparticle@Metal-Organic Framework Nanoprobes for Luminescent/Magnetic Dual-Mode Targeted Imaging

(2015) Yantao Li et al.   ADVANCED MATERIALS

Multifunctional Bioconjugate for Cancer Cell-Targeted Theranostics

(2015) Wei Du et al.   BIOCONJUGATE CHEMISTRY

TPGS-stabilized NaYbF4:Er upconversion nanoparticles for dual-modal fluorescent/CT imaging and anticancer drug delivery to overcome multi-drug resistance

(2015) Gan Tian et al.   BIOMATERIALS

Reversal of multidrug resistance by co-delivery of paclitaxel and lonidamine using a TPGS and hyaluronic acid dual-functionalized liposome for cancer treatment

(2015) Assogba G. Assanhou et al.   BIOMATERIALS

Telodendrimer nanocarrier for co-delivery of paclitaxel and cisplatin: A synergistic combination nanotherapy for ovarian cancer treatment

(2015) Liqiong Cai et al.   BIOMATERIALS

Preparation and identification of multifunctional mesoporous silica nanoparticles for in vitro and in vivo dual-mode imaging, theranostics, and targeted tracking

(2015) Ming-Hsien Chan et al.   BIOMATERIALS

Multi-functional self-fluorescent unimolecular micelles for tumor-targeted drug delivery and bioimaging

(2015) Guojun Chen et al.   BIOMATERIALS

Photosensitizer conjugated iron oxide nanoparticles for simultaneous in vitro magneto-fluorescent imaging guided photodynamic therapy

(2015) Md Nafiujjaman et al.   CHEMICAL COMMUNICATIONS

Multifunctional liposomes having target specificity, temperature-triggered release, and near-infrared fluorescence imaging for tumor-specific chemotherapy

(2015) Kenji Kono et al.   JOURNAL OF CONTROLLED RELEASE

Hard and soft nanoparticles for image-guided surgery in nanomedicine

(2015) Erica Locatelli et al.   JOURNAL OF NANOPARTICLE RESEARCH

SERS-fluorescence dual mode nanotags for cervical cancer detection using aptamers conjugated to gold-silver nanorods

(2015) Suwussa Bamrungsap et al.   MICROCHIMICA ACTA

Multifunctional nanoparticle–EpCAM aptamer bioconjugates: A paradigm for targeted drug delivery and imaging in cancer therapy

(2015) Manasi Das et al.   Nanomedicine-Nanotechnology Biology and Medicine

Matrix metalloproteinase triggered size-shrinkable gelatin-gold fabricated nanoparticles for tumor microenvironment sensitive penetration and diagnosis of glioma

(2015) Shaobo Ruan et al.   Nanoscale

Dendrimer-Assisted Formation of Fe3O4/Au Nanocomposite Particles for Targeted Dual Mode CT/MR Imaging of Tumors

(2015) Hongdong Cai et al.   Small

CD44v6 Monoclonal Antibody-Conjugated Gold Nanostars for Targeted Photoacoustic Imaging and Plasmonic Photothermal Therapy of Gastric Cancer Stem-like Cells

(2015) Shujing Liang et al.   Theranostics

Facile synthesis of hyaluronic acid-modified Fe3O4/Au composite nanoparticles for targeted dual mode MR/CT imaging of tumors

(2015) Yong Hu et al.   Journal of Materials Chemistry B

Hybrid nanoprobes of bismuth sulfide nanoparticles and CdSe/ZnS quantum dots for mouse computed tomography/fluorescence dual mode imaging

(2015) Jun Chen et al.   JOURNAL OF NANOBIOTECHNOLOGY

Upconversion Fluorescence-SERS Dual-Mode Tags for Cellular and in Vivo Imaging

(2014) Xiaojuan Niu et al.   ACS Applied Materials & Interfaces

Targeted Iron-Oxide Nanoparticle for Photodynamic Therapy and Imaging of Head and Neck Cancer

(2014) Dongsheng Wang et al.   ACS Nano

Multifunctional Liquid Crystal Nanoparticles for Intracellular Fluorescent Imaging and Drug Delivery

(2014) Christopher M. Spillmann et al.   ACS Nano

Gel-Liposome-Mediated Co-Delivery of Anticancer Membrane-Associated Proteins and Small-Molecule Drugs for Enhanced Therapeutic Efficacy

(2014) Tianyue Jiang et al.   ADVANCED FUNCTIONAL MATERIALS

Real-Time In Vivo Quantitative Monitoring of Drug Release by Dual-Mode Magnetic Resonance and Upconverted Luminescence Imaging

(2014) Jianan Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A fullerene-based multi-functional nanoplatform for cancer theranostic applications

(2014) Jinjin Shi et al.   BIOMATERIALS

Prussian blue coated gold nanoparticles for simultaneous photoacoustic/CT bimodal imaging and photothermal ablation of cancer

(2014) Lijia Jing et al.   BIOMATERIALS

Doxorubicin loaded singlet-oxygen producible polymeric micelle based on chlorine e6 conjugated pluronic F127 for overcoming drug resistance in cancer

(2014) Hyung Park et al.   BIOMATERIALS

Targeted cancer theranostics using alpha-tocopheryl succinate-conjugated multifunctional dendrimer-entrapped gold nanoparticles

(2014) Jingyi Zhu et al.   BIOMATERIALS

Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs

(2014) Lin Zhu et al.   BIOMATERIALS

Encapsulating tantalum oxide into polypyrrole nanoparticles for X-ray CT/photoacoustic bimodal imaging-guided photothermal ablation of cancer

(2014) Yushen Jin et al.   BIOMATERIALS

A tumor-targeting near-infrared laser-triggered drug delivery system based on GO@Ag nanoparticles for chemo-photothermal therapy and X-ray imaging

(2014) Jinjin Shi et al.   BIOMATERIALS

Multifunctional liposomes loaded with paclitaxel and artemether for treatment of invasive brain glioma

(2014) Xiu-Ying Li et al.   BIOMATERIALS

Biodegradable polymeric vesicles containing magnetic nanoparticles, quantum dots and anticancer drugs for drug delivery and imaging

(2014) Fei Ye et al.   BIOMATERIALS

Multifunctional graphene quantum dots for simultaneous targeted cellular imaging and drug delivery

(2014) Xiaojuan Wang et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Biocompatible mesoporous silica-coated superparamagnetic manganese ferrite nanoparticles for targeted drug delivery and MR imaging applications

(2014) Banalata Sahoo et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Role of non-covalent and covalent interactions in cargo loading capacity and stability of polymeric micelles

(2014) Xiyu Ke et al.   JOURNAL OF CONTROLLED RELEASE

Responsive polymer–fluorescent carbon nanoparticle hybrid nanogels for optical temperature sensing, near-infrared light-responsive drug release, and tumor cell imaging

(2014) Hui Wang et al.   Nanoscale

‘One-pot’ synthesis of multifunctional GSH–CdTe quantum dots for targeted drug delivery

(2014) Xiaoqin Chen et al.   NANOTECHNOLOGY

Bio-inspired Development of a Dual-Mode Nanoprobe for MRI and Raman Imaging

(2014) Kuk-Youn Ju et al.   Small

In vitro interaction of colloidal nanoparticles with mammalian cells: What have we learned thus far?

(2014) Moritz Nazarenus et al.   Beilstein Journal of Nanotechnology

Magnetic/Upconversion Fluorescent NaGdF4:Yb,Er Nanoparticle-Based Dual-Modal Molecular Probes for Imaging Tiny Tumors in Vivo

(2013) Chunyan Liu et al.   ACS Nano

Iron Oxide @ Polypyrrole Nanoparticles as a Multifunctional Drug Carrier for Remotely Controlled Cancer Therapy with Synergistic Antitumor Effect

(2013) Chao Wang et al.   ACS Nano

Facile Synthesis of Magnetite/Perfluorocarbon Co-Loaded Organic/Inorganic Hybrid Vesicles for Dual-Modality Ultrasound/Magnetic Resonance Imaging and Imaging-Guided High-Intensity Focused Ultrasound Ablation

(2013) Dechao Niu et al.   ADVANCED MATERIALS

NIR-Triggered Anticancer Drug Delivery by Upconverting Nanoparticles with Integrated Azobenzene-Modified Mesoporous Silica

(2013) Jianan Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The targeted co-delivery of DNA and doxorubicin to tumor cells via multifunctional PEI-PEG based nanoparticles

(2013) Chunxi Liu et al.   BIOMATERIALS

Targeted CT/MR dual mode imaging of tumors using multifunctional dendrimer-entrapped gold nanoparticles

(2013) Qian Chen et al.   BIOMATERIALS

Ultra-small BaGdF5-based upconversion nanoparticles as drug carriers and multimodal imaging probes

(2013) Dongmei Yang et al.   BIOMATERIALS

Gold nanoparticle cluster–plasmon-enhanced fluorescent silica core–shell nanoparticles for X-ray computed tomography–fluorescence dual-mode imaging of tumors

(2013) Koichiro Hayashi et al.   CHEMICAL COMMUNICATIONS

A multifunctional nanoprobe based on Au–Fe3O4 nanoparticles for multimodal and ultrasensitive detection of cancer cells

(2013) Jian Liu et al.   CHEMICAL COMMUNICATIONS

Multifunctional dendrimer-based nanoparticles for in vivo MR/CT dual-modal molecular imaging of breast cancer

(2013) Kangan Li et al.   International Journal of Nanomedicine

Dual anticancer drug/superparamagnetic iron oxide-loaded PLGA-based nanoparticles for cancer therapy and magnetic resonance imaging

(2013) N. Schleich et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

SPIO nanoparticle-stabilized PAA-F127 thermosensitive nanobubbles with MR/US dual-modality imaging and HIFU-triggered drug release for magnetically guided in vivo tumor therapy

(2013) Hsin-Yang Huang et al.   JOURNAL OF CONTROLLED RELEASE

Sub-10 nm Fe3O4@Cu2–xS Core–Shell Nanoparticles for Dual-Modal Imaging and Photothermal Therapy

(2013) Qiwei Tian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rattle-Structured Multifunctional Nanotheranostics for Synergetic Chemo-/Radiotherapy and Simultaneous Magnetic/Luminescent Dual-Mode Imaging

(2013) Wenpei Fan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Vivo Multimodality Imaging and Cancer Therapy by Near-Infrared Light-Triggered trans-Platinum Pro-Drug-Conjugated Upconverison Nanoparticles

(2013) Yunlu Dai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In situ preparation of gold nanoparticle-loaded lysozyme–dextran nanogels and applications for cell imaging and drug delivery

(2013) Huanxin Cai et al.   Nanoscale

Synthesis of Au–Fe3O4heterostructured nanoparticles for in vivo computed tomography and magnetic resonance dual model imaging

(2013) Jing Zhu et al.   Nanoscale

Multifunctional Gold Nanostar Conjugates for Tumor Imaging and Combined Photothermal and Chemo-therapy

(2013) Haiyan Chen et al.   Theranostics

Theranostic Probe Based on Lanthanide-Doped Nanoparticles for Simultaneous In Vivo Dual-Modal Imaging and Photodynamic Therapy

(2012) Yong Il Park et al.   ADVANCED MATERIALS

Hybrid Nanoparticles for Detection and Treatment of Cancer

(2012) Michael J. Sailor et al.   ADVANCED MATERIALS

Europium-doped gadolinium sulfide nanoparticles as a dual-mode imaging agent for T1-weighted MR and photoluminescence imaging

(2012) Jongjin Jung et al.   BIOMATERIALS

Multifunctional QD-based co-delivery of siRNA and doxorubicin to HeLa cells for reversal of multidrug resistance and real-time tracking

(2012) Jin-Ming Li et al.   BIOMATERIALS

Superparamagnetic PLGA-iron oxide microcapsules for dual-modality US/MR imaging and high intensity focused US breast cancer ablation

(2012) Yang Sun et al.   BIOMATERIALS

Theranostic liposomes of TPGS coating for targeted co-delivery of docetaxel and quantum dots

(2012) Madaswamy S. Muthu et al.   BIOMATERIALS

Multifunctional Fe3O4@C@Ag hybrid nanoparticles as dual modal imaging probes and near-infrared light-responsive drug delivery platform

(2012) Jian Chen et al.   BIOMATERIALS

Doxorubicin loaded superparamagnetic PLGA-iron oxide multifunctional microbubbles for dual-mode US/MR imaging and therapy of metastasis in lymph nodes

(2012) Chengcheng Niu et al.   BIOMATERIALS

Au-nanoparticle coated mesoporous silica nanocapsule-based multifunctional platform for ultrasound mediated imaging, cytoclasis and tumor ablation

(2012) Xia Wang et al.   BIOMATERIALS

Multifunctional dendrimer-entrapped gold nanoparticles for dual mode CT/MR imaging applications

(2012) Shihui Wen et al.   BIOMATERIALS

Recent advances in synthesis and surface modification of lanthanide-doped upconversion nanoparticles for biomedical applications

(2012) Min Lin et al.   BIOTECHNOLOGY ADVANCES

Temozolomide loaded PLGA-based superparamagnetic nanoparticles for magnetic resonance imaging and treatment of malignant glioma

(2012) You Ling et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Gold Nanorods Performing as Dual-Modal Nanoprobes via Metal-Enhanced Fluorescence (MEF) and Surface-Enhanced Raman Scattering (SERS)

(2012) Ana M. Gabudean et al.   Journal of Physical Chemistry C

Multifunctional Fe3O4/TaOx Core/Shell Nanoparticles for Simultaneous Magnetic Resonance Imaging and X-ray Computed Tomography

(2012) Nohyun Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multifunctional Branched Gold–Carbon Nanotube Hybrid for Cell Imaging and Drug Delivery

(2012) L. Minati et al.   LANGMUIR

A functionalized graphene oxide-iron oxide nanocomposite for magnetically targeted drug delivery, photothermal therapy, and magnetic resonance imaging

(2012) Xinxing Ma et al.   Nano Research

Folate Decorated Dual Drug Loaded Nanoparticle: Role of Curcumin in Enhancing Therapeutic Potential of Nutlin-3a by Reversing Multidrug Resistance

(2012) Manasi Das et al.   PLoS One

Remote activation of biomolecules in deep tissues using near-infrared-to-UV upconversion nanotransducers

(2012) M. K. G. Jayakumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hybrid gold-iron oxide nanoparticles as a multifunctional platform for biomedical application

(2012) Clare Hoskins et al.   JOURNAL OF NANOBIOTECHNOLOGY

Noninvasive MRI-SERS Imaging in Living Mice Using an Innately Bimodal Nanomaterial

(2011) Mehmet V. Yigit et al.   ACS Nano

Traceable Multifunctional Micellar Nanocarriers for Cancer-Targeted Co-delivery of MDR-1 siRNA and Doxorubicin

(2011) Xiao-Bing Xiong et al.   ACS Nano

Multifunctional Nanoemulsion Platform for Imaging Guided Therapy Evaluated in Experimental Cancer

(2011) Anita Gianella et al.   ACS Nano

Cellular Uptake and Fate of PEGylated Gold Nanoparticles Is Dependent on Both Cell-Penetration Peptides and Particle Size

(2011) Eunkeu Oh et al.   ACS Nano

The Controlled Display of Biomolecules on Nanoparticles: A Challenge Suited to Bioorthogonal Chemistry

(2011) W. Russ Algar et al.   BIOCONJUGATE CHEMISTRY

Dual docetaxel/superparamagnetic iron oxide loaded nanoparticles for both targeting magnetic resonance imaging and cancer therapy

(2011) You Ling et al.   BIOMATERIALS

Multifunctional nanoprobes for upconversion fluorescence, MR and CT trimodal imaging

(2011) Huaiyong Xing et al.   BIOMATERIALS

Multifunctional nanoparticles for upconversion luminescence/MR multimodal imaging and magnetically targeted photothermal therapy

(2011) Liang Cheng et al.   BIOMATERIALS

Multifunctional nanocarrier mediated co-delivery of doxorubicin and siRNA for synergistic enhancement of glioma apoptosis in rat

(2011) Du Cheng et al.   BIOMATERIALS

Multifunctional nanoparticles for multimodal imaging and theragnosis

(2011) Dong-Eun Lee et al.   CHEMICAL SOCIETY REVIEWS

Reversal of multidrug resistance by co-delivery of tariquidar (XR9576) and paclitaxel using long-circulating liposomes

(2011) Niravkumar R. Patel et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Toxicology and clinical potential of nanoparticles

(2011) Lara Yildirimer et al.   Nano Today

Nanoparticle actuated hollow drug delivery vehicles

(2011) Esther Amstad et al.   Nanomedicine

Upconversion nanoparticles: synthesis, surface modification and biological applications

(2011) Meng Wang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Fabrication of SERS-fluorescence dual modal nanoprobes and application to multiplex cancer cell imaging

(2011) Sangyeop Lee et al.   Nanoscale

The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers

(2011) Carlee E. Ashley et al.   NATURE MATERIALS

PLGA/polymeric liposome for targeted drug and gene co-delivery

(2010) Hanjie Wang et al.   BIOMATERIALS

Polymer-Stabilized Lanthanide Fluoride Nanoparticle Aggregates as Contrast Agents for Magnetic Resonance Imaging and Computed Tomography

(2010) Evelyn Ning Man Cheung et al.   CHEMISTRY OF MATERIALS

Upconverting luminescent nanoparticles for use in bioconjugation and bioimaging

(2010) Heike S Mader et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Quantum Dot Capped Magnetite Nanorings as High Performance Nanoprobe for Multiphoton Fluorescence and Magnetic Resonance Imaging

(2010) Hai-Ming Fan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Vitro and in Vivo Studies of FePt Nanoparticles for Dual Modal CT/MRI Molecular Imaging

(2010) Shang-Wei Chou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases

(2010) E. S. Olson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantum dots: a powerful tool for understanding the intricacies of nanoparticle-mediated drug delivery

(2009) James B Delehanty et al.   Expert Opinion on Drug Delivery

Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance

(2009) Yogesh Patil et al.   JOURNAL OF CONTROLLED RELEASE

A dual CT-MR dendrimer contrast agent as a surrogate marker for convection-enhanced delivery of intracerebral macromolecular therapeutic agents

(2008) Celeste Aida S. Regino et al.   Contrast Media & Molecular Imaging

Gadolinium Chelate Coated Gold Nanoparticles As Contrast Agents for Both X-ray Computed Tomography and Magnetic Resonance Imaging

(2008) Christophe Alric et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantum dots versus organic dyes as fluorescent labels

(2008) Ute Resch-Genger et al.   NATURE METHODS