Multisite tumor sampling enhances the detection of intratumor heterogeneity at all different temporal stages of tumor evolution

Multisite tumor sampling: a new tumor selection method to enhance intratumor heterogeneity detection

(2017) José I. López et al.   HUMAN PATHOLOGY

Tumor Heterogeneity: Will It Change What Pathologists Do

(2017) Fredrik T. Bosman   PATHOBIOLOGY

How to study and overcome tumor heterogeneity with circulating biomarkers: The breast cancer case

(2017) Valentina Appierto et al.   SEMINARS IN CANCER BIOLOGY

Future perspectives of circulating tumor DNA in colorectal cancer

(2017) C Nadal et al.   TUMOR BIOLOGY

Cancer Liquid Biopsy: Is It Ready for Clinic?

(2017) Ying Pan et al.   IEEE Pulse

Intratumor Heterogeneity in Primary Kidney Cancer Revealed by Metabolic Profiling of Multiple Spatially Separated Samples within Tumors

(2017) Takatsugu Okegawa et al.   EBioMedicine

Identification of neutral tumor evolution across cancer types

(2016) Marc J Williams et al.   NATURE GENETICS

Tumour heterogeneity: principles and practical consequences

(2016) Giorgio Stanta et al.   VIRCHOWS ARCHIV

The degree of intratumor mutational heterogeneity varies by primary tumor sub-site

(2016) Levi G. Ledgerwood et al.   Oncotarget

Regional and temporal heterogeneity of epithelial ovarian cancer tumor biopsies: implications for therapeutic strategies

(2016) Lara Paracchini et al.   Oncotarget

Tumour sampling method can significantly influence gene expression profiles derived from neoadjuvant window studies

(2016) Dominic A. Pearce et al.   Scientific Reports

How should clinicians address intratumour heterogeneity in clear cell renal cell carcinoma?

(2015) Aspasia Soultati et al.   CURRENT OPINION IN UROLOGY

Many private mutations originate from the first few divisions of a human colorectal adenoma

(2015) Haeyoun Kang et al.   JOURNAL OF PATHOLOGY

A Big Bang model of human colorectal tumor growth

(2015) Andrea Sottoriva et al.   NATURE GENETICS

Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution

(2015) Shaoping Ling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regional biases in mutation screening due to intratumoural heterogeneity of prostate cancer

(2014) Tae-Min Kim et al.   JOURNAL OF PATHOLOGY

Clonal evolution in breast cancer revealed by single nucleus genome sequencing

(2014) Yong Wang et al.   NATURE

Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity

(2014) Andriy Marusyk et al.   NATURE

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

(2014) Marco Gerlinger et al.   NATURE GENETICS

Renal tumors with clear cells. A review

(2013) José I. López   PATHOLOGY RESEARCH AND PRACTICE

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE