Article
Oncology
Yanling Chen, Qing Lu, Weibin Zhang, Jiaying Cao, Yi Dong, Wenping Wang
Summary: A predictive nomogram based on clinical and ultrasound findings was established to distinguish combined hepatocellular-cholangiocarcinoma (CHC) from other subtypes of primary liver cancers (PLCs). The nomogram showed promising performance and clinical usefulness in differentiating CHC from hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC).
FRONTIERS IN ONCOLOGY
(2022)
Article
Gastroenterology & Hepatology
Maria Reig, Giuseppe Cabibbo
Summary: The potential impact of DAAs in BCLC-B/C stage patients with HCC is understudied, as HCC patients have been excluded from DAA trials. The decision on using DAAs should be made based on individual patient profiles.
JOURNAL OF HEPATOLOGY
(2021)
Review
Gastroenterology & Hepatology
Aurelie Beaufrere, Julien Calderaro, Valerie Paradis
Summary: Combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a tumor with both hepatocytic and biliary differentiation, whose diagnosis is primarily based on morphology and immunostaining, with a prognosis worse than hepatocellular carcinoma and treatment limited to surgery.
JOURNAL OF HEPATOLOGY
(2021)
Article
Medicine, General & Internal
Ling Gao, Jia-Yan Huang, Zi-Jian Lu, Qiang Lu
Summary: The CEUS characteristics of synchronous CHC and HCC are different. CEUS features in combination with clinical information could help in effective diagnosis, clinical decision-making and better prognosis.
WORLD JOURNAL OF CLINICAL CASES
(2022)
Article
Oncology
Zhizhi Tan, Jiawu Li, Zhenru Wu, Zhengling Zhou, Lulu Yang, Yan Luo
Summary: The purpose of this study was to compare the sonographic features of primary hepatic neuroendocrine tumors (PHNETs) to those of non-hepatitis B and non-hepatitis C hepatocellular carcinoma (NBNC-HCC) on contrast-enhanced ultrasound (CEUS). The results showed that PHNET was more common in women, while NBNC-HCC was more common in men. PHNET had larger tumor size compared to NBNC-HCC. In addition, CEUS revealed that most PHNETs exhibited heterogeneous enhancement in the arterial phase, washout in the portal venous and late phases, and early washout being more likely than NBNC-HCC.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Haibin Tu, Siyi Feng, Lihong Chen, Yujie Huang, Juzhen Zhang, Xiaoxiong Wu
Summary: This study constructed a new model based on contrast-enhanced ultrasound (CEUS) and serological biomarkers to predict the early recurrence (ER) of primary hepatocellular carcinoma after hepatectomy. Data from 466 patients were collected, and univariate analysis and multivariate Cox proportional hazards regression model were used to identify independent prognostic factors for tumor recurrence. The CEUSS model showed high accuracy in predicting ER and can serve as a new tool for individualized treatment.
FRONTIERS IN ONCOLOGY
(2023)
Review
Oncology
Mariella Faccia, Matteo Garcovich, Maria Elena Ainora, Laura Riccardi, Maurizio Pompili, Antonio Gasbarrini, Maria Assunta Zocco
Summary: The evaluation of tumor response to anti-cancer therapy is critical in oncology for treatment planning and follow-up strategies. Contrast-enhanced ultrasound (CEUS) and dynamic CEUS are promising tools for early tumor response evaluation. This article provides a general review of the usefulness of CEUS in monitoring HCC response to therapy, highlighting its role in different disease stages.
Article
Health Care Sciences & Services
Si-Si Huang, Meng-Xuan Zuo, Chuan-Miao Xie
Summary: This study aimed to investigate the preoperative predictors of microvascular invasion (MVI) in hepatitis B virus (HBV)-related combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CCA) patients. The independent predictors of MVI were found to be gamma-glutamyl transpeptidase, peritumoral enhancement, and multiple nodules. The established prediction score showed satisfactory performance in predicting MVI and may facilitate prognostic stratification.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Virology
Giacomo Emanuele Maria Rizzo, Giuseppe Cabibbo, Antonio Craxi
Summary: Hepatitis B virus (HBV) infection is associated with the risk of developing hepatocellular carcinoma (HCC), with or without liver cirrhosis, through various mechanisms. The molecular profile of HBV-HCC is constantly being studied, and it is the result of altered molecular pathways, changes in the microenvironment, and DNA damage. Proper management of HBV-related liver disease is crucial for prevention and treatment of HCC.
Article
Oncology
Meng Xue, Xiaona Lin, Qiu-Xiong Lin, Xiaoyong Pu, Jiumin Liu, Xing-Fang Li, Jun Hou, Xudong Liu, Ren Chen
Summary: This study found that HBV infection was associated with an increased risk of HCC compared to HEV infection, and that HEV infection may mitigate the promoting impact of HBV on HCC development.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Review
Biochemistry & Molecular Biology
Nicholas Noverati, Rukaiya Bashir-Hamidu, Dina Halegoua-DeMarzio, Hie-Won Hann
Summary: Hepatitis B virus is a significant cause of hepatocellular carcinoma globally. The complex mechanisms of this virus include interactions with the host's immune system. Factors such as stress can amplify these mechanisms. Chronic stress, harmful to health, can suppress or activate the host's defense system, leading to tumor initiation and progression in liver cancer. Chronic stress, often overlooked, should be recognized as a potential risk factor.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Acoustics
Y. A. N. L. I. N. G. Chen, Q. I. N. G. Lu, Y. U. L. Zhu, B. E. I. J. I. A. N. Huang, Y. Dong, W. E. N. P. I. N. G. Wang
Summary: The study aimed to evaluate the predictive value of pre-operative clinical information and contrast-enhanced ultrasound (CEUS) imaging characteristics in diagnosing microvascular invasion (MVI) in combined hepatocellular-cholangiocarcinoma (CHC) patients. The results showed that heterogeneous enhancement and marked washout on CEUS were independent predictors of MVI in CHC. Patients with MVI had earlier recurrence after hepatectomy.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2022)
Article
Oncology
Yan Zhou, Shanshan Yin, Lin Zhao, Xiang Zhang, Meng Li, Jianmin Ding, Kun Yan, Xiang Jing
Summary: The combination of CEUS and CT/MRI LI-RADS with serum tumor markers shows promising diagnostic performance in differentiating cHCC-CCAs from HCCs.
FRONTIERS IN ONCOLOGY
(2022)
Article
Acoustics
Huan-Ling Guo, Xin Zheng, Mei-Qing Cheng, Dan Zeng, Hui Huang, Xiao-Yan Xie, Ming-De Lu, Ming Kuang, Wei Wang, Meng-Fei Xian, Li-Da Chen
Summary: The diagnostic performance of CEUS features and US features were better than CEUS LI-RADS, especially when including information such as washout time and tumor boundary, which significantly improved the differentiation between p-HCC and ICC.
JOURNAL OF ULTRASOUND IN MEDICINE
(2022)
Review
Oncology
Florian Rossner, Bruno Valentin Sinn, David Horst
Summary: This review discusses the histomorphological classification and diagnosis methods of combined hepatocellular carcinoma-cholangiocarcinoma (cHCC-CCA), as well as the molecular foundation for potential therapeutic approaches. cHCC-CCA is a rare primary liver cancer composed of hepatocellular and cholangiocellular differentiated cells. The classification of this cancer has evolved over time, with the latest WHO classification emphasizing morphological diagnosis and introducing new subtypes. Immunohistochemical markers have limited value for diagnosis, but recent discoveries in molecular pathway regulation may lead to new therapeutic approaches for this challenging disease.
Article
Urology & Nephrology
Xiaoer Zhang, Wenxin Xu, Tongyi Huang, Jingzhi Huang, Chunyang Zhang, Yutong Zhang, Xiaoyan Xie, Ming Xu
Summary: This study analyzed ultrasound features in patients with SHPT and developed a model based on clinical-ultrasonographic features to predict the severity of SHPT. Serum calcium, serum phosphorus, and total volume of PTGs were identified as independent predictors of serum iPTH level. The nomogram developed showed good calibration and discrimination in predicting SHPT severity.
Article
Oncology
Jingzhi Huang, Baoxian Liu, Manxia Lin, Xiaoer Zhang, Yanling Zheng, Xiaoyan Xie, Ming Xu, Xiaohua Xie
Summary: Ultrasound-guided percutaneous radiofrequency ablation (RFA) provides effective local tumor control for neuroendocrine tumor liver metastases (NETLM) with low morbidity. The study found a high technical efficacy rate and no major complications during the RFA treatment. Patients with Ki-67 < 5% had longer progression-free survival after percutaneous RFA treatment.
INTERNATIONAL JOURNAL OF HYPERTHERMIA
(2022)
Article
Oncology
Yuqing Guo, Manying Li, Xiaoer Zhang, Xiaohua Xie, Yanling Zheng, Ming Xu, Ming Kuang, Kaixin Yu, Xiaoyan Xie, Guangliang Huang
Summary: The study found that 3DUS-FI can be used for real-time guidance in precise needle placement and may further improve the efficacy of liver thermal ablation.
INTERNATIONAL JOURNAL OF HYPERTHERMIA
(2022)
Article
Nutrition & Dietetics
Ling Luo, Junzhao Ye, Congxiang Shao, Yansong Lin, Yanhong Sun, Shiting Feng, Wei Wang, Bihui Zhong
Summary: This study investigated the relationships between serum vitamin D levels and metabolism, liver fat content, and fibrosis in patients with metabolic-associated fatty liver disease (MAFLD) with and without chronic hepatitis B (CHB) infection. The study found that serum vitamin D levels were lower in MAFLD patients compared to healthy controls and patients with CHB alone or overlapping with MAFLD. After adjusting for confounding factors, vitamin D was significantly negatively correlated with liver fat content in MAFLD patients but not in CHB with MAFLD patients. Vitamin D deficiency was associated with the severity of metabolic abnormalities and steatosis in MAFLD patients independent of lifestyle factors, but not in MAFLD with CHB patients.
Article
Radiology, Nuclear Medicine & Medical Imaging
Chao-qun Li, Xin Zheng, Huan-ling Guo, Mei-qing Cheng, Yang Huang, Xiao-yan Xie, Ming-de Lu, Ming Kuang, Wei Wang, Li-da Chen
Summary: This study aimed to establish and confirm an ultrasomics model for differentiating combined hepatocellular cholangiocarcinoma (CHC) from hepatocellular carcinoma (HCC). The ultrasomics model showed higher ability in differentiating CHC from HCC, which may be helpful in clinical diagnosis.
BMC MEDICAL IMAGING
(2022)
Article
Oncology
Sui Peng, Shuling Chen, Wei Hu, Jie Mei, Xuezhen Zeng, Tianhong Su, Wei Wang, Zebin Chen, Han Xiao, Qian Zhou, Bin Li, Yubin Xie, Huanjing Hu, Minghui He, Yanyan Han, Longqing Tang, Yifan Ma, Xiaoshuang Li, Xiangjun Zhou, Zihao Dai, Zelong Liu, Jiehui Tan, Lixia Xu, Shaoqiang Li, Shunli Shen, Dongming Li, Jiaming Lai, Baogang Peng, Zhenwei Peng, Ming Kuang
Summary: This study demonstrates that personalized neoantigen-loaded immunotherapy as adjuvant treatment has the potential to reduce hepatocellular carcinoma recurrence after curative therapy, is feasible, and has a good safety profile.
CANCER IMMUNOLOGY RESEARCH
(2022)
Article
Gastroenterology & Hepatology
Tingfeng Wu, Junzhao Ye, Congxiang Shao, Yansong Lin, Wei Wang, Shiting Feng, Bihui Zhong
Summary: This study aimed to evaluate the association between Lp(a) levels and the risk of carotid atherosclerosis in MAFLD patients with advanced fibrosis, and identified different relationships between Lp(a) levels and liver fat content in different types of MAFLD patients.
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ming Liu, Xiao-Ju Li, Xiao-Er Zhang, Ming Kuang, Xiao-Yan Xie, Guang-Liang Huang
Summary: This study evaluated the local efficacy, safety, and long-term outcomes of combined radiofrequency ablation (RFA) and multipronged ethanol ablation (EA) in the treatment of unfavorable hepatocellular carcinoma (HCC) and determined prognostic factors for survival. The results showed that combined RFA and multipronged EA is a safe and effective treatment for unfavorable HCC, especially for perivascular tumors.
DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY
(2023)
Article
Acoustics
Meng-Fei Xian, Wei Li, Wen-Tong Lan, Dan Zeng, Wen-Xuan Xie, Ming-De Lu, Yang Huang, Wei Wang
Summary: This study aimed to develop an effective strategy for accurate diagnosis of focal liver lesions (FLLs) in patients with non-high risk for hepatocellular carcinoma (HCC). The combination of clinical risk stratification criteria and CEUS criteria showed high accuracy in identifying benign lesions and HCCs in the intermediate-risk group.
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
Article
Biology
Qinghua Huang, Liangrun Zhao, Guanqing Ren, Xiaoyi Wang, Chunying Liu, Wei Wang
Summary: Cardiovascular diseases (CVD) are a major threat to human health and the leading cause of death worldwide. This paper proposes a nested attention-guided deep learning model, NAG-Net, for accurate segmentation of carotid Lumen-intima interface (LII) and Media-adventitia interface (MAI). NAG-Net incorporates task-related clinical domain knowledge and allows for direct obtaining of fine contours without complicated post-processing steps.
COMPUTERS IN BIOLOGY AND MEDICINE
(2023)
Article
Medicine, General & Internal
Wen-Juan Tong, Shao-Hong Wu, Mei-Qing Cheng, Hui Huang, Jin-Yu Liang, Chao-Qun Li, Huan-Ling Guo, Dan-Ni He, Yi-Hao Liu, Han Xiao, Hang-Tong Hu, Si-Min Ruan, Ming-De Li, Ming-De Lu, Wei Wang
Summary: To optimize the integration of AI decision aids and reduce workload in thyroid nodule management, personalized AI needs to be incorporated into radiologists' decision-making processes. The study compares the diagnostic performance and workload reduction of an optimized AI strategy with a traditional all-AI strategy.
Article
Acoustics
Ze-Rong Huang, Lv Li, Hui Huang, Mei-Qing Cheng, Ming- De Li, Huan-Ling Guo, Rui-Fang Lu, Wei Wang, Wei Li, Li- Da Chen
Summary: The objective of this study was to evaluate the value of pre-operative multimodal data in predicting early and late recurrence of hepatocellular carcinoma after curative treatment. Clinical parameters, 2-D shear wave elastography, and contrast-enhanced ultrasound were found to be independently associated with early recurrence. Contrast-enhanced ultrasound and 2-D shear wave elastography were significant predictors of early recurrence at different time points. The multimodal model performed the best in predicting early recurrence of hepatocellular carcinoma.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Zhong Liu, Wei Li, Ziqi Zhu, Huiying Wen, Ming-de Li, Chao Hou, Hui Shen, Bin Huang, Yudi Luo, Wei Wang, Xin Chen
Summary: This study developed a deep learning model that integrates ultrasound contrast-enhanced micro-flow (CEMF) cines, B-mode images, and clinical parameters to improve the diagnosis of significant liver fibrosis (>= F2) in patients with chronic hepatitis B (CHB).
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Si-min Ruan, Hui Huang, Mei-qing Cheng, Man-xia Lin, Hang-tong Hu, Yang Huang, Ming-de Li, Ming-de Lu, Wei Wang
Summary: This study established a shear-wave elastography combined with contrast-enhanced ultrasound algorithm for the differentiation of focal liver lesions. The results showed that the algorithm had higher accuracy and clinical benefits in detecting malignant lesions, and it also showed promising results in patients with normal liver backgrounds.
Article
Radiology, Nuclear Medicine & Medical Imaging
Ming-De Li, Mei-Qing Cheng, Li-Da Chen, Hang-Tong Hu, Jian-Chao Zhang, Si-Min Ruan, Hui Huang, Ming Kuang, Ming-De Lu, Wei Li, Wei Wang
Summary: The study systematically assessed the reproducibility of radiomics features from ultrasound images, finding that wavelet and shearlet features showed the best reproducibility across all procedures.
EUROPEAN RADIOLOGY
(2022)
Article
Acoustics
Ting Luo, Zhen Wang, Xiaoling Yu, Zhiyu Han, Zhigang Cheng, Fangyi Liu, Jie Yu, Ping Liang
Summary: This study aimed to investigate the contribution of subtotal ultrasound-guided percutaneous microwave ablation (MWA) to the inhibition of programmed cell death protein-1 (PD-1) in advanced hepatocellular carcinoma (HCC). The results showed that MWA >50% AR could enhance immune-related gene expression, activate CD8+ T cells, and thereby boost the immunomodulatory effect of PD-1 inhibitors.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Letter
Acoustics
Bernard Cosyns, Sharon L. Mulvagh
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Article
Acoustics
Keith Barron, Michael Blaivas, Laura Blaivas, John Sadler, Isadora Deal
Summary: Researchers investigated whether quantitative ultrasound assessment of hyoid bone movement during induced swallowing would predict the failure of traditional assessment methods in stroke patients. They found that manual ultrasound measurement was not accurate in predicting the assessment outcome, but a machine learning algorithm showed substantial agreement with the results, suggesting its potential for improving dysphagia assessment.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Article
Acoustics
Sheng Chen, Yi-Jie Qiu, Qi Zhang, Xiu-Yun Lu, Yun-Lin Huang, Yi Dong, Wen-Ping Wang
Summary: The impact of hepatocellular carcinoma (HCC) tumor size on Sonazoid contrast-enhanced ultrasound (CEUS) enhancement features was evaluated. The study found that tumor size had a significant impact on the washout features of HCC lesions, with smaller lesions exhibiting a later occurrence of washout.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Article
Acoustics
Sean Mcgrath, Yu-Jack Shen, Masato Aragaki, Yamato Motooka, Takamasa Koga, Alexander Gregor, Nicholas Bernards, Emmanuel Cherin, Christine E. M. Demore, Kazuhiro Yasufuku, Naomi Matsuura
Summary: This study assessed the imaging ability of CE-EBUS in vitro and in vivo and found that CE-EBUS can produce contrast imaging comparable to commercial pre-clinical and clinical ultrasound systems. CE-EBUS has the potential for clinical characterization of mediastinal lymph nodes in lung cancer patients.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Review
Acoustics
Ahmed M. Al-Jumaily, Hassan Liaquat, Sharad Paul
Summary: This article presents a comprehensive review on the effect of various operational parameters of focused ultrasound (FUS) on the injury zone produced by ultrasound beams for different dermatological applications. The article highlights the efficient operational parameters of FUS to enhance pain relief during surgery and make skin treatment more affordable. Additionally, a prospective future technique for efficient FUS is discussed.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Article
Acoustics
Celine Porte, Thomas Lisson, Matthias Kohlen, Finn von Maltzahn, Stefanie Dencks, Saskia von Stillfried, Marion Piepenbrock, Anne Rix, Anshuman Dasgupta, Patrick Koczera, Peter Boor, Elmar Stickeler, Georg Schmitz, Fabian Kiessling
Summary: This study aimed to refine ULM for breast cancer patients by optimizing the measurement protocol, identifying translational challenges, and combining ULM with shear wave elastography. The results showed that the settings for microbubble injection strongly influence ULM images, requiring optimized protocols for different indications. Patient and examiner motion were identified as the main translational challenges for ULM.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Review
Acoustics
Jocelyne Rivera, Antonia Digklia, Anna S. Christou, James Anibal, Katherine A. Vallis, Bradford J. Wood, Eleanor Stride
Summary: Immunotherapy is a major modality in cancer medicine, but its efficacy is limited and it has potential side effects. Ultrasound and cavitation agents can enhance the effectiveness of immunotherapy and stimulate immune responses.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Article
Acoustics
Shyamala Guruvare, Shripad Hebbar, Lakshmi Bai, Padmapriya Jaiprakash, Deepa Reddy, Deepa Hc
Summary: This study assessed the accuracy of 3-D surface rendering of 2-D ultrasound images of the uterus using FMRA software for mapping uterine fibroids compared to pathological evaluation. The results showed good correlation between the two methods in terms of fibroid size and location. Inter-observer analysis also demonstrated reproducibility of measurements from two sonologists using the 3-D model.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Article
Acoustics
Yuting Shen, Jiadong Zhang, Daohuai Jiang, Zijian Gao, Yuwei Zheng, Feng Gao, Fei Gao
Summary: This study proposes a straightforward simulation approach based on superposed Wave (s-Wave) to accelerate photoacoustic simulation. By manipulating the phase and amplitude of sensor data, the computation time is significantly reduced. The results show that s-Wave exhibits a speed improvement >2000 times compared with k-Wave in a sparse system configuration, and in terms of optimization-based image reconstruction, the reconstruction time is reduced by approximately 50 times.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Article
Acoustics
Jason Voorneveld, Johan G. Bosch
Summary: This study assesses the effect of spatial velocity gradients (SVGs) on block matching, and finds that the sinusoidal flow wavelength and SVG angle have significant impact on the bias and precision of block matching.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Article
Acoustics
Kartini Rahmat, Nazimah Ab Mumin, Wei Lin Ng, Nur Aishah Mohd Taib, Wai Yee Chan, Marlina Tanty Ramli Hamid
Summary: This study demonstrates the value of ABUS as an adjunct to DBT in breast screening and diagnosis, with improved cancer detection rates.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Article
Acoustics
Jieyu Hu, Sindre Hellum Olaisen, Erik Smistad, Havard Dalen, Lasse Lovstakken
Summary: This study introduces a fully automated, real-time method for measuring left atrial volume in echocardiography using a neural network to identify key time points and segmentation techniques. The results show that this method provides comparable accuracy to manual measurements while saving time and reducing operator variability, with an average volume difference of 2.9 mL for 2-D and 7.8 mL for 3-D imaging. The application of pseudo-labeling improves the stability of volume curves and the accuracy of end-systole measurement.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Article
Acoustics
Anam Bhatti, Takuro Ishii, Yoshifumi Saijo
Summary: A new protocol for fabricating a microflow phantom with bifurcated geometry at a superficial region was proposed in this study. Ultrasound imaging confirmed the successful creation of the desired flow tract with bifurcation at a depth of 2-5 mm. The experiments demonstrated the validity of the proposed protocol for creating a microscale intricate flow tract with desired dimensions and depth. This new phantom will facilitate further improvement in ultrasound technologies for precise visualization of superficial complex vasculatures.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
Article
Acoustics
Nima Mobadersany, Pengcheng Liang, Paul Kemper, Elisa E. Konofagou
Summary: This study describes a technique for manufacturing arterial phantoms using polyvinyl alcohol and evaluates the use of pulse wave imaging (PWI) to assess plaque stiffness. The results show that PWI can distinguish between plaques of different stiffness and composition.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2024)
