A Novel Approach for Pathway Analysis of GWAS Data Highlights Role of BMP Signaling and Muscle Cell Differentiation in Colorectal Cancer Susceptibility

Genetic architecture of colorectal cancer

(2015) Ulrike Peters et al.   GUT

Biological interpretation of genome-wide association studies using predicted gene functions

(2015) Tune H. Pers et al.   Nature Communications

Silencing BMP-2 expression inhibits A549 and H460 cell proliferation and migration

(2014) Heying Chu et al.   Diagnostic Pathology

Estimating the heritability of colorectal cancer

(2014) Shuo Jiao et al.   HUMAN MOLECULAR GENETICS

Identification of Coding Exon 3 Duplication in the BMPR1A Gene in a Patient with Juvenile Polyposis Syndrome

(2014) Junya Yamaguchi et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Melanoma NOS1 expression promotes dysfunctional IFN signaling

(2014) Qiuzhen Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Explaining additional genetic variation in complex traits

(2014) Matthew R. Robinson et al.   TRENDS IN GENETICS

VEGAS2: Software for More Flexible Gene-Based Testing

(2014) Aniket Mishra et al.   Twin Research and Human Genetics

SOX15 is a candidate tumor suppressor in pancreatic cancer with a potential role in Wnt/β-catenin signaling

(2013) K L Thu et al.   ONCOGENE

INRICH: interval-based enrichment analysis for genome-wide association studies

(2012) Phil H. Lee et al.   BIOINFORMATICS

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis

(2012) Ulrike Peters et al.   GASTROENTEROLOGY

Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling

(2012) Astrid De Boeck et al.   GUT

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

Comparison of Methods for Competitive Tests of Pathway Analysis

(2012) Marina Evangelou et al.   PLoS One

A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response

(2012) Jenny Fung Ling Chau et al.   Nature Communications

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Gene set analysis of genome-wide association studies: Methodological issues and perspectives

(2011) Lily Wang et al.   GENOMICS

Calpain 2-dependent IκBα degradation mediates CPT-11 secondary resistance in colorectal cancer xenografts

(2011) Nina Fenouille et al.   JOURNAL OF PATHOLOGY

A Versatile Gene-Based Test for Genome-wide Association Studies

(2010) Jimmy Z. Liu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Analysing biological pathways in genome-wide association studies

(2010) Kai Wang et al.   NATURE REVIEWS GENETICS

Pathway Commons, a web resource for biological pathway data

(2010) E. G. Cerami et al.   NUCLEIC ACIDS RESEARCH

Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits

(2010) Ayellet V. Segrè et al.   PLoS Genetics

Gene Ontology Analysis of GWA Study Data Sets Provides Insights into the Biology of Bipolar Disorder

(2009) Peter Holmans et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease

(2009) Kai Wang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

FGF10/FGFR2 signal induces cell migration and invasion in pancreatic cancer

(2008) S Nomura et al.   BRITISH JOURNAL OF CANCER

BMP7 influences proliferation, migration, and invasion of breast cancer cells

(2008) Emma-Leena Alarmo et al.   CANCER LETTERS

SMAD6 Contributes to Patient Survival in Non-Small Cell Lung Cancer and Its Knockdown Reestablishes TGF-  Homeostasis in Lung Cancer Cells

(2008) H.-S. Jeon et al.   CANCER RESEARCH

The Bone Morphogenetic Protein Pathway Is Inactivated in the Majority of Sporadic Colorectal Cancers

(2008) Liudmila L. Kodach et al.   GASTROENTEROLOGY

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

(2008)   NATURE GENETICS

PID: the Pathway Interaction Database

(2008) Carl F. Schaefer et al.   NUCLEIC ACIDS RESEARCH