Deep sequencing of the TP53 gene reveals a potential risk allele for non–small cell lung cancer and supports the negative prognostic value of TP53 variants

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

APR-246 (PRIMA-1 MET ) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines

(2016) Christophe Deben et al.   CANCER LETTERS

TP53 and MDM2 genetic alterations in non-small cell lung cancer: Evaluating their prognostic and predictive value

(2016) Christophe Deben et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Prognostic and Predictive Effect of TP53 Mutations in Patients with Non–Small Cell Lung Cancer from Adjuvant Cisplatin–Based Therapy Randomized Trials: A LACE-Bio Pooled Analysis

(2016) Xiaoli Ma et al.   Journal of Thoracic Oncology

Significance of TP53 mutations as predictive markers of adjuvant cisplatin-based chemotherapy in completely resected non-small-cell lung cancer

(2014) Xiaoli Ma et al.   Molecular Oncology

VariantDB: a flexible annotation and filtering portal for next generation sequencing data

(2014) Geert Vandeweyer et al.   Genome Medicine

Prognostic value ofTP53,KRASandEGFRmutations in nonsmall cell lung cancer: the EUELC cohort

(2012) Chiara Scoccianti et al.   EUROPEAN RESPIRATORY JOURNAL

Combined Effect of Genetic Polymorphisms in P53, P73, and MDM2 on Non-small Cell Lung Cancer Survival

(2011) Li Liu et al.   Journal of Thoracic Oncology

Allelic Expression Imbalance of TP53 Mutated and Polymorphic Alleles in Head and Neck Tumors

(2011) Federica Ganci et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

MUT-TP53 2.0: a novel versatile matrix for statistical analysis of TP53 mutations in human cancera

(2010) Thierry Soussi et al.   HUMAN MUTATION

Association of DNA Repair Gene Polymorphisms With Response to Platinum-Based Doublet Chemotherapy in Patients With Non–Small-Cell Lung Cancer

(2010) Kouya Shiraishi et al.   JOURNAL OF CLINICAL ONCOLOGY

Association ofp53codon 72 polymorphism andMDM2SNP309 with clinical outcome of advanced nonsmall cell lung cancer

(2008) Ji-Youn Han et al.   CANCER

Growing clinical evidence for the interaction of the p53 genotype and response to induction chemotherapy in advanced non–small cell lung cancer

(2008) Daniela Kandioler et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

p53 mRNA controls p53 activity by managing Mdm2 functions

(2008) Marco M. Candeias et al.   NATURE CELL BIOLOGY