Paving the path for invasion: The polyedric role of LASP1 in cancer

LASP-1 induces proliferation, metastasis and cell cycle arrest at the G2/M phase in gallbladder cancer by down-regulating S100P via the PI3K/AKT pathway

(2016) ZhiZhen Li et al.   CANCER LETTERS

LASP-1, regulated by miR-203, promotes tumor proliferation and aggressiveness in human non-small cell lung cancer

(2016) Jie Zheng et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Focal adhesions, stress fibers and mechanical tension

(2016) Keith Burridge et al.   EXPERIMENTAL CELL RESEARCH

The tumor-suppressive function of miR-1 by targeting LASP1 and TAGLN2 in esophageal squamous cell carcinoma

(2016) Yan-Yan Du et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Identification and Validation of Reference Genes for RT-qPCR Studies of Hypoxia in Squamous Cervical Cancer Patients

(2016) Christina S. Fjeldbo et al.   PLoS One

MicroRNA-218 inhibits the proliferation, migration, and invasion and promotes apoptosis of gastric cancer cells by targeting LASP1

(2016) Le-Le Wang et al.   TUMOR BIOLOGY

Epigenetically regulated miR-145 suppresses colon cancer invasion and metastasis by targeting LASP1

(2016) Wei Wang et al.   Oncotarget

Regulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1)

(2016) Marcel Endres et al.   Oncotarget

Loss of the 14-3-3σ is essential for LASP1-mediated colorectal cancer progression via activating PI3K/AKT signaling pathway

(2016) Ziyun Shao et al.   Scientific Reports

LASP1-S100A11 axis promotes colorectal cancer aggressiveness by modulating TGFβ/Smad signaling

(2016) Ya Niu et al.   Scientific Reports

The cytoskeletal protein LASP-1 differentially regulates migratory activities of choriocarcinoma cells

(2015) S. E. Segerer et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Roles of Nebulin Family Members in the Heart

(2015) Marie-Louise Bang et al.   CIRCULATION JOURNAL

Molecular characterization of LASP-1 expression reveals vimentin as its new partner in human hepatocellular carcinoma cells

(2015) ALESSANDRO SALVI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex

(2015) N Duvall-Noelle et al.   ONCOGENE

An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein

(2015) Martin F. Orth et al.   Oncotarget

HIF-1 is a critical target of pancreatic cancer

(2015) Jihui Hao   OncoImmunology

LASP1 is a novel BCR-ABL substrate and a phosphorylation-dependent binding partner of CRKL in chronic myeloid leukemia

(2015) Jochen J. Frietsch et al.   Oncotarget

Proteomic Identification of LASP-1 Down-regulation After RNAi Urokinase Silencing in Human Hepatocellular Carcinoma Cells

(2015) Alessandro Salvi et al.   NEOPLASIA

LASP1 Is a HIF1  Target Gene Critical for Metastasis of Pancreatic Cancer

(2014) T. Zhao et al.   CANCER RESEARCH

LIM and SH3 Protein 1 Induces TGF -Mediated Epithelial-Mesenchymal Transition in Human Colorectal Cancer by Regulating S100A4 Expression

(2014) H. Wang et al.   CLINICAL CANCER RESEARCH

Structural analysis of the genome of breast cancer cell line ZR-75-30 identifies twelve expressed fusion genes

(2012) Ina Schulte et al.   BMC GENOMICS

LIM and SH3 protein 1, a promoter of cell proliferation and migration, is a novel independent prognostic indicator in hepatocellular carcinoma

(2012) Hui Wang et al.   EUROPEAN JOURNAL OF CANCER

miR-203 inhibits the migration and invasion of esophageal squamous cell carcinoma by regulating LASP1

(2012) NOBUYOSHI TAKESHITA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Nuclear import of LASP-1 is regulated by phosphorylation and dynamic protein–protein interactions

(2012) S Mihlan et al.   ONCOGENE

Silencing of miR-1-1 and miR-133a-2 cluster expression by DNA hypermethylation in colorectal cancer

(2012) WEI-SHONE CHEN et al.   ONCOLOGY REPORTS

Lasp-1 Regulates Podosome Function

(2012) Miriam Stölting et al.   PLoS One

LASP-1, a Novel Urinary Marker for Detection of Bladder Cancer

(2012) Peter Ardelt et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines

(2011) Giuditta Viticchiè et al.   CELL CYCLE

Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer

(2010) J J Frietsch et al.   BRITISH JOURNAL OF CANCER

Role of LIM and SH3 Protein 1 (LASP1) in the Metastatic Dissemination of Medulloblastoma

(2010) C. Traenka et al.   CANCER RESEARCH

miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity

(2010) M-P Puisségur et al.   CELL DEATH AND DIFFERENTIATION

Promotion of colorectal cancer growth and metastasis by the LIM and SH3 domain protein 1

(2010) L. Zhao et al.   GUT

Lost in migration

(2010) George S Mack et al.   NATURE BIOTECHNOLOGY

Functional role of LASP1 in cell viability and its regulation by microRNAs in bladder cancer

(2010) Takeshi Chiyomaru et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Cancer Cells in Transit: The Vascular Interactions of Tumor Cells

(2009) Konstantinos Konstantopoulos et al.   Annual Review of Biomedical Engineering

Novel β-Propeller of the BTB-Kelch Protein Krp1 Provides a Binding Site for Lasp-1 That Is Necessary for Pseudopodial Extension

(2009) Christopher H. Gray et al.   JOURNAL OF BIOLOGICAL CHEMISTRY