Mutation-promoting molecular networks of uncontrolled inflammation

Helicobacter pylori-induced Sonic Hedgehog Expression is Regulated by NFκB Pathway Activation: The Use of a Novel In vitro Model to Study Epithelial Response to Infection

(2014) Michael A. Schumacher et al.   HELICOBACTER

The role of APOBEC3B in chondrosarcoma

(2014) ZHE JIN et al.   ONCOLOGY REPORTS

MicroRNAs play a central role in molecular dysfunctions linking inflammation with cancer

(2013) Esmerina Tili et al.   IMMUNOLOGICAL REVIEWS

Loss of the Transcription Factor GLI1 Identifies a Signaling Network in the Tumor Microenvironment Mediating KRAS Oncogene-induced Transformation

(2013) Lisa D. Mills et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Natural Borneol, a Monoterpenoid Compound, Potentiates Selenocystine-Induced Apoptosis in Human Hepatocellular Carcinoma Cells by Enhancement of Cellular Uptake and Activation of ROS-Mediated DNA Damage

(2013) Jianyu Su et al.   PLoS One

Viral Hepatitis Induces Hepatocellular Cancer: What Can We Learn from Epidemiology Comparing Iran and Worldwide Findings?

(2012) Elisabeth Smolle et al.   Hepatitis Monthly

Role of theHelicobacter pylori-Induced inflammatory response in the development of gastric cancer

(2012) Acacia Lamb et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets

(2012) Mauricio da Silva Krause et al.   JOURNAL OF ENDOCRINOLOGY

Contribution of HOGG1 Ser326Cys Polymorphism to the Development of Prostate Cancer in Smokers: Meta-Analysis of 2779 Cases and 3484 Controls

(2012) Bin Xu et al.   PLoS One

BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway

(2012) Egest J. Pone et al.   Nature Communications

Negative Supercoiling Creates Single-Stranded Patches of DNA That Are Substrates for AID–Mediated Mutagenesis

(2012) Jahan-Yar Parsa et al.   PLoS Genetics

Chronic intestinal inflammation: inflammatory bowel disease and colitis-associated colon cancer

(2012) Deborah C. Rubin et al.   Frontiers in Immunology

Chronic occupational exposure to hexavalent chromium causes DNA damage in electroplating workers

(2011) Xu-Hui Zhang et al.   BMC PUBLIC HEALTH

Prostate cancer and inflammation: the evidence

(2011) Karen S Sfanos et al.   HISTOPATHOLOGY

The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation

(2010) Gerasimos P Sykiotis et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Suppression of mutagenesis by 8-hydroxy-2′-deoxyguanosine 5′-triphosphate (7,8-dihydro-8-oxo-2′-deoxyguanosine 5′-triphosphate) by human MTH1, MTH2, and NUDT5

(2010) Mika Hori et al.   FREE RADICAL BIOLOGY AND MEDICINE

Death pathways triggered by activated Ras in cancer cells

(2010) Jean et al.   Frontiers in Bioscience-Landmark

GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation

(2009) O. Nolan-Stevaux et al.   GENES & DEVELOPMENT

Primary biliary cirrhosis is associated with altered hepatic microRNA expression

(2009) Kerstien A. Padgett et al.   JOURNAL OF AUTOIMMUNITY

Hydrogen peroxide induces autophagic cell death in C6 glioma cells via BNIP3-mediated suppression of the mTOR pathway

(2009) Yu Jeong Byun et al.   NEUROSCIENCE LETTERS

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Is NF-κB a good target for cancer therapy? Hopes and pitfalls

(2008) Véronique Baud et al.   NATURE REVIEWS DRUG DISCOVERY

Oxidative DNA damage and its repair in rat spleen following subchronic exposure to aniline

(2008) Huaxian Ma et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Hedgehog signaling pathway: Development of antagonists for cancer therapy

(2008) Jingwu Xie   Current Oncology Reports