Article
Virology
Svetoslav N. Slavov, Elaine Santos, Marta R. Hespanhol, Evandra S. Rodrigues, Rodrigo Haddad, Eugenia M. A. Ubiali, Dimas T. Covas, Simone Kashima
Summary: During a large DENV outbreak in Ribeirao Preto city, Brazil, 8475 blood donations were tested for DENV viremia, with 3 samples testing positive for DENV RNA. Two samples were serotyped as DENV-1, and one as DENV-2. The prevalence of anti-DENV IgG among blood donors was 50.8%.
JOURNAL OF MEDICAL VIROLOGY
(2021)
Article
Infectious Diseases
Marielton dos Passos Cunha, Amaro Nunes Duarte-Neto, Shahab Zaki Pour, Barbara Brito de Souza Pereira, Yeh-Li Ho, Beatriz Perondi, Jaques Sztajnbok, Venancio Avancini Ferreira Alves, Luiz Fernando Ferraz da Silva, Marisa Dolhnikoff, Paulo Hilario Nascimento Saldiva, Paolo Marinho de Andrade Zanotto
Summary: From 2016 to 2019, the largest outbreak of the Yellow Fever virus (YFV) in the Americas occurred in southeastern Brazil. The virus was transmitted through a sylvatic cycle near densely populated areas, such as the metropolitan region of Sao Paulo. The analysis of whole-genome sequences revealed that the outbreak originated in Goias in 2014 and spread through Minas Gerais before reaching Sao Paulo. The virus dispersed towards the east and south regions of Sao Paulo but did not establish an urban transmission cycle in the metropolitan region of Sao Paulo. The YFV from the south of Rio de Janeiro met with the virus moving east, while the virus carried to the south reached the southern states of Brazil.
PLOS NEGLECTED TROPICAL DISEASES
(2022)
Article
Infectious Diseases
Rebeca Costa Castelo Branco, Patricia Brasil, Joselio Maria Galvao Araujo, Flavia Oliveira Cardoso, Zulmira Silva Batista, Valeria Maria Souza Leitao, Marcos Antonio Custodio Neto da Silva, Lailson Oliveira de Castro, Joanna Gardel Valverde, Selma Maria Bezerra Jeronimo, Joselia Alencar Lima, Raimunda Ribeiro da Silva, Maria do Carmo Lacerda Barbosa, Luciane Maria Oliveira Brito, Marcelo Antonio Pascoal Xavier, Maria Do Desterro Soares Brandao Nascimento
Summary: This study investigated the prevalence of Zika infection in asymptomatic pregnant women attending two public maternities in MaranhAo state, Northeast Brazil. The findings show that ZIKV infection was common in umbilical cord and placental samples, but did not result in morphological or psychomotor abnormalities in newborns at birth. These results highlight the importance of awareness of the risk of ZIKV infection during pregnancy and the need for improved healthcare and strategic planning for obstetric and neonatal care.
PLOS NEGLECTED TROPICAL DISEASES
(2021)
Article
Environmental Sciences
Marcia Akemi Yamasoe, Nilton Manuel Evora Rosario, Samantha Novaes Santos Martins Almeida, Martin Wild
Summary: The study found a dimming effect on surface solar irradiation in Sao Paulo between 1961 and the early 1980s, with no brightening effect observed. There was an increasing trend in cloud cover fraction and surface downward irradiation, while sunshine duration and diurnal temperature range showed decreasing trends.
ATMOSPHERIC CHEMISTRY AND PHYSICS
(2021)
Article
Clinical Neurology
Sonja E. Leonhard, Susan Halstead, Suzannah B. Lant, Maria de Fatima Pessoa Militao de Albuquerque, Carlos Alexandre Antunes de Brito, Livia Brito Bezerra de Albuquerque, Mark A. Ellul, Rafael Freitas de Oliveira Franca, Dawn Gourlay, Michael J. Griffiths, Adelia Maria de Miranda Henriques-Souza, Maria I. de Morais Machado, Raquel Medialdea-Carrera, Ravi Mehta, Roberta da Paz Melo, Solange D. Mesquita, Alvaro J. P. Moreira, Lindomar J. Pena, Marcela Lopes Santos, Lance Turtle, Tom Solomon, Hugh J. Willison, Bart C. Jacobs, Maria L. Brito Ferreira
Summary: This study investigated the clinical phenotype and antibody signature of GBS patients following Zika virus and chikungunya virus outbreaks in Northeast Brazil. The majority of patients had evidence of recent arbovirus infection, with longer hospital stays observed in those infected with both Zika and chikungunya viruses.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2021)
Article
Clinical Neurology
Laura Silveira Tanisaka, Laercio da Silva Paiva, Luis Eduardo Werneck de Carvalho, Fernando Luiz Affonso Fonseca, David Feder, Vania Barbosa do Nascimento, Fernando Adami
Summary: Globally, stroke is a significant cause of death and disability. The impact of COVID-19 on the healthcare system has affected stroke care. Researchers have found that after the onset of COVID-19, patients are hesitant to seek medical help for stroke due to fear of exposure.
CEREBROVASCULAR DISEASES
(2022)
Article
Environmental Sciences
Ornella Luminati, Bartolomeu Ledebur de Antas de Campos, Benjamin Fluckiger, Alexandra Brentani, Martin Roosli, Gunther Fink, Kees de Hoogh
Summary: The study developed robust models to predict NO2 residential exposure in the study area of the Western Region Birth Cohort in Sao Paulo, finding that 67% of the population in the area is exposed to NO2 values over the WHO suggested annual guideline.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Mayumi C. M. Hirye, Diogenes Salas Alves, Angelo Salvador Filardo Jr, Timon McPhearson, Fabien Wagner
Summary: Urban landslides are increasing worldwide due to human-induced changes in hillsides. These events mainly result in low-intensity damages to housing and infrastructure. A study in Sao Paulo, Brazil, used a social-ecological-technological system approach to model landslide occurrence, considering dynamic socioeconomic and infrastructural conditions along with climatic and geophysical factors. Antecedent rainfall and terrain slope were found to be the most important variables, while factors such as informal settlements and the number of households also contributed. The study highlights the importance of local ordinances and public policies to prevent urban landslides and addresses the future risk of increased rainfall.
Article
Multidisciplinary Sciences
Osmar Pinto Neto, Deanna M. Kennedy, Jose Clark Reis, Yiyu Wang, Ana Carolina Brisola Brizzi, Gustavo Jose Zambrano, Joabe Marcos de Souza, Wellington Pedroso, Rodrigo Cunha de Mello Pedreiro, Bruno de Matos Brizzi, Ellysson Oliveira Abinader, Renato Amaro Zangaro
Summary: The optimal strategy for controlling COVID-19 transmission dynamics in Sao Paulo, Brazil involves gradually reducing social distancing over time with a stepping-down reduction every 80 days. Increasing the percentage of people strictly following protective guidelines by 5-10% is also crucial in reducing social distancing. This framework can be applied to model transmission dynamics in other regions and organizations.
NATURE COMMUNICATIONS
(2021)
Article
Geography
Erica Akemi Goto, A. Marcela Suarez, Haiyun Ye
Summary: This study assessed the social vulnerability to natural hazards in Sao Paulo city using the Social Vulnerability Index (SoVI). The results showed that demographic and average household size were the most important contributing factors, and vulnerable neighborhoods were mainly located in the southern areas and outskirts of the city. The findings can be used by local authorities for emergency planning and policy making.
Article
Environmental Sciences
Lais A. Maroubo, Marcos R. Moreira-Silva, Jose Jeronimo Teixeira, Marcos F. S. Teixeira
Summary: This study evaluated the spatiotemporal variation of cadmium, lead, and copper ions in groundwater wells in the Santo Anastacio stratigraphic subdivision of the Bauru aquifer system. The results showed the direct relationship between monthly metal flow and rainfall, with different seasonal variations for Cd2+/Pb2+ and Cu2+. Cadmium and lead were found to come from minerals in the aquifer, while copper presence was linked to anthropogenic activities in the region's agriculture.
Article
Microbiology
Ana Paula Moreira Salles, Ana Catharina de Seixas Santos Nastri, Yeh-Li Ho, Luciana Vilas Boas Casadio, Deyvid Emanuel Amgarten, Santiago Justo Arevalo, Michele Soares Gomes-Gouvea, Flair Jose Carrilho, Fernanda de Mello Malta, Joao Renato Rebello Pinho
Summary: This study assessed the genetic diversity of the yellow fever virus during the outbreak in Sao Paulo from 2016 to 2019. The researchers identified new subclades and described their sequence signatures, as well as determined their locations and time of origin. These findings contribute to future virological and epidemiological studies.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Infectious Diseases
Maisa Carla Pereira Parra, Camila Lorenz, Bruno Henrique Goncalves de Aguiar Milhim, Margareth Regina Dibo, Marluci Monteiro Guirado, Francisco Chiaravalloti-Neto, Mauricio Lacerda Nogueira
Summary: We conducted mosquito-based Zika virus surveillance in Sa & Sim;o Paulo State, Brazil from 2015 to 2018. We found high infection rates in the summer, and areas with human Zika cases had clusters of Zika-positive mosquitoes.
INFECTION GENETICS AND EVOLUTION
(2022)
Article
Environmental Sciences
Michelle Raess, Alexandra Brentani, Bartolomeu Ledebur de Antas de Campos, Benjamin Fluckiger, Kees de Hoogh, Gunther Fink, Martin Roosli
Summary: Noise pollution has negative health consequences that are increasingly relevant in rapidly urbanizing areas. This study developed LUR models to assess spatial variability of community noise in the Western Region of Sao Paulo, Brazil, finding high noise exposure levels and identifying main predictors such as distance to roads, educational facilities, NDVI, residential areas, and slum areas. The study suggests that LUR modelling with geographic predictor data is a promising and efficient approach for noise exposure assessment in low- and middle-income countries.
ENVIRONMENTAL RESEARCH
(2021)
Article
Astronomy & Astrophysics
Maciel Pinero Sanchez, Amauri Pereira de Oliveira, Ramon Perez Varona, Janet Valdes Tito, Georgia Codato, Rita Yuri Ynoue, Flavia Noronha Dutra Ribeiro, Edson Pereira Marques Filho, Lucas Cardoso da Silveira
Summary: The study found that the low-level jet in the metropolitan region of Sao Paulo mainly occurs during nighttime and early morning, with significant seasonal variations. In addition, urban heat island intensity, surface inversion layer strength, and air pollutant concentrations are negatively correlated with LLJ intensity.
EARTH AND SPACE SCIENCE
(2022)
Letter
Infectious Diseases
Victoria Simionatto Zucherato, Mariane Evaristo, Elaine Vieira Santos, Ralyria Mello, Erika Donizetti Candido, Danielle Bastos Araujo, Marta Giovanetti, Luiz Carlos Junior Alcantara, Daiani Cristina Ciliao-Alves, Rodrigo Haddad, Dimas Tadeu Covas, Simone Kashima, Svetoslav Nanev Slavov
JOURNAL OF INFECTION
(2022)
Article
Virology
Simone Kashima, Svetoslav N. Slavov, Marta Giovanetti, Evandra S. Rodrigues, Jose S. L. Patane, Vincent L. Viala, Elaine V. Santos, Mariane Evaristo, Loyze P. O. de Lima, Antonio J. Martins, Claudia R. dos Santos Barros, Elaine C. Marqueze, Pedro M. M. Garibaldi, Natasha N. Ferreira, Glenda R. Moraes, Ricardo A. Brassaloti, Raquel L. R. C. Cassano, Pilar D. S. C. Mariani, Joao P. Kitajima, David Schlesinger, Rafael S. Bezerra, Patricia A. Assato, Felipe A. S. da Costa, Mirele Daiana Poleti, Jessika C. C. Lesbon, Elisangela C. Mattos, Cecilia A. Banho, Livia Sacchetto, Rejane M. T. Grotto, Jayme A. Souza-Neto, Vagner Fonseca, Luiz C. J. de Alcantara, Mauricio L. Nogueira, Heidge Fukumasu, Luiz L. Coutinho, Marcos Borges, Rodrigo T. Calado, Maria C. Elias, Sandra C. Sampaio, Dimas T. Covas
Summary: This study characterized the circulation of the SARS-CoV-2 Lambda variant in Sao Paulo State, Brazil. Among approximately 8000 newly sequenced genomes, seven Lambda isolates were identified, with three possibly due to contact transmission. Vaccinated patients showed mild symptoms, while one required hospitalization among those testing positive for Lambda variant.
JOURNAL OF MEDICAL VIROLOGY
(2022)
Article
Neurosciences
Evandra Strazza Rodrigues, Suellen Salustiano, Elaine Vieira Santos, Svetoslav Nanev Slavov, Virginia Picanco-Castro, Juliana Matos Maconetto, Tissiana Marques de Haes, Osvaldo Massaiti Takayanagui, Dimas Tadeu Covas, Simone Kashima
Summary: In this study, a sensitive multiplex real-time PCR method was successfully optimized for the simultaneous detection and quantification of HTLV-1 proviral load and endogenous gene. The method was found to be effective in monitoring and following up the clinical progression of HTLV-1 disease in infected individuals.
JOURNAL OF NEUROVIROLOGY
(2022)
Article
Virology
Rafael dos Santos Bezerra, Joao Paulo Bianchi Ximenez, Marta Giovanetti, Victoria Simionatto Zucherato, Helen Tayana Bitencourt, Ana Zimmermann, Luiz Carlos Junior Alcantara Junior, Dimas Tadeu Covas, Simone Kashima, Svetoslav Nanev Slavov
Summary: Viral metagenomics can reveal the composition of viruses in health and disease. This study evaluated the metagenomics of blood donors from different regions in Brazil and found differences in viral composition.
Article
Microbiology
Marta Giovanetti, Luiz Augusto Pereira, Talita Emile Ribeiro Adelino, Vagner Fonseca, Joilson Xavier, Allison de Araujo Fabri, Svetoslav Nanev Slavov, Poliana da Silva Lemos, William de Almeida Marques, Simone Kashima, Jose Lourenco, Tulio de Oliveira, Carlos Frederico Campelo de Albuquerque, Carla Freitas, Cassio Roberto Leonel Peterka, Rivaldo Venancio da Cunha, Ana Flavia Mendonca, Vinicius Lemes da Silva, Luiz Carlos Junior Alcantara
Summary: This study retrospectively investigated the transmission dynamics of the Zika virus in the state of Goias, Brazil, using genomic and epidemiological methods. The results showed a decline in reported cases due to the accumulation of herd immunity and multiple independent introductions of the Asian lineage over time, indicating a complex transmission dynamic in the region.
MICROBIOLOGY SPECTRUM
(2022)
Article
Biochemistry & Molecular Biology
Leticia B. C. Penariol, Carolina H. Thome, Patricia A. Tozetti, Carlos R. K. Paier, Fabiana O. Buono, Kamila C. Peronni, Maristela D. Orellana, Dimas T. Covas, Maria E. A. Moraes, Wilson A. Silva, Julio C. Rosa-e-Silva, Rui A. Ferriani, Vitor M. Faca, Omero B. Poli-Neto, Daniel G. Tiezzi, Juliana Meola
Summary: This study used multi-omics approaches to analyze the transcriptome and proteome data of endometriosis MenSCs, and identified several genes and proteins related to the disease, as well as modulated signaling pathways. The findings suggest that the chronic inflammatory endometrial microenvironment can regulate MenSCs, providing insights into the pathogenesis of endometriosis and its implications for regenerative medicine.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Hematology
Victoria Simionatto Zucherato, Pericles Natan Mendes da Costa, Marta Giovanetti, Luciana Maria Fontanari Krause, Daiani Cristina Ciliao Alves, Renata Maria Alencar Moreira, Barbara Maciel Sidou Pimentel, Rodrigo Haddad, Hellen Tayana Bitencourt, Massimo Ciccozzi, Luiz Carlos Junior Alcantara, Simone Kashima, Dimas Tadeu Covas, Svetoslav Nanev Slavov
Summary: The study evaluated the prevalence of MCPyV DNA among Brazilian blood donors and found an overall prevalence of 1.1%, with similar rates in different regions.
TRANSFUSION CLINIQUE ET BIOLOGIQUE
(2023)
Correction
Virology
Jessika Cristina Chagas Lesbon, Mirele Daiana Poleti, Elisangela Chicaroni de Mattos Oliveira, Jose Salvatore Leister Patane, Luan Gaspar Clemente, Vincent Louis Viala, Gabriela Ribeiro, Marta Giovanetti, Luiz Carlo de Alcantara Jr, Olivia Teixeira, Maria Cristina Nonato, Loyze Paola Oliveira de Lima, Antonio Jorge Martins, Claudia Renata dos Santos Barros, Elaine Cristina Marqueze, Jardelina de Souza Todao Bernardino, Debora Botequio Moretti, Ricardo Augusto Brassaloti, Raquel de Lello Rocha Campos Cassano, Pilar Drummond Sampaio Correa Mariani, Svetoslav Nanev Slavov, Rafael Bezerra dos Santos, Evandra Strazza Rodrigues, Elaine Vieira Santos, Josiane Serrano Borges, Debora Glenda Lima de la Roque, Joao Paulo Kitajima, Bibiana Santos, Patricia Akemi Assato, Felipe Allan da Silva da Costa, Cecilia Artico Banho, Livia Sacchetto, Marilia Mazzi Moraes, Melissa Palmieri, Fabiana Erica Vilanova da Silva, Rejane Maria Tommasini Grotto, Jayme A. Souza-Neto, Mauricio Lacerda Nogueira, Luiz Lehman Coutinho, Rodrigo Tocantins Calado, Raul Machado Neto, Dimas Tadeu Covas, Simone Kashima, Maria Carolina Elias, Sandra Coccuzzo Sampaio, Heidge Fukumasu
Article
Public, Environmental & Occupational Health
Maria Carolina Elias, Svetoslav Nanev Slavov, Alex Ranieri Jeronimo Lima, Antonio Jorge Martins, Claudia Renata dos Santos Barros, Debora Botequio Moretti, Eduardo L. Araujo, Elaine Cristina Marqueze, Gabriela Ribeiro, Gabriela Mauric Frossard Ribeiro, Jardelina Souza Todao Bernardino, Jaqueline Reginato Koser, Luan Gaspar Clemente, Luiz Aurelio Campos Crispin, Luiz Carlos Alcantara Jr, Luiz Lehmann Coutinho, Marta Giovanetti, Quetura Oliveira Silva, Raul Machado Neto, Ricardo Haddad, Simone Kashima, Vincent Louis Viala, Dimas Tadeu Covas, Sandra Coccuzzo Sampaio
Summary: Brazil has been severely affected by the SARS-CoV-2 pandemic and has been a continuous source of virus variants. Due to insufficient infrastructure in some regions of the country, the Butantan Institute established a mobile laboratory (LabMovel) to conduct SARS-CoV-2 testing and monitor the pandemic in key areas.
Article
Multidisciplinary Sciences
Dimas Tadeu Covas, Ariane de Jesus Lopes de Abreu, Carolina Zampirolli Dias, Rafaela Vansan Ferreira, Ramon Goncalves Pereira, Guilherme Silva Julian
Summary: This study aims to describe the adverse events of COVID-19 vaccines in pregnant and postpartum women in Brazil. The results support the recommendation of vaccination for these groups, but further studies with longer observation time are still needed to provide more comprehensive safety evidence.
Article
Virology
Patricia Akemi Assato, Luan Gaspar Clemente, Marta Giovanetti, Gabriela Ribeiro, Alex Ranieri Jeronimo Lima, Melissa Palmieri, Leonardo Nazario de Moraes, Simone Kashima, Heidge Fukumasu, Mauricio Lacerda Nogueira, Luiz Carlos Alcantara, Aline Lais Nicolodelli, Antonio Jorge Martins, Bruna Petry, Cecilia Artico Banho, Claudia Renata Dos Santos Barros, Cristina Tschorny Moncau-Gadbem, Debora Botequio Moretti, Debora Glenda De La Roque, Elaine Cristina Marqueze, Elisangela Chicaroni Mattos, Fabiana Erica Vilanova Da Silva, Felipe Allan Da Silva Da Costa, Giselle Cacherik, Jardelina De Souza Todao Bernardino, Jessika Cristina Chagas Lesbon, Livia Sacchetto, Loyze Paola Oliveira De Lima, Luiz Artur Vieira Caldeira, Maiara Martininghi, Marilia Mazzi Moraes, Mirele Daiana Poleti, Pedro De Queiroz Cattony Neto, Raquel De Lello Rocha Campos Cassano, Ricardo Augusto Brassaloti, Svetoslav Nanev Slavov, Vincent Louis Viala, Luiz Lehmann Coutinho, Rejane Maria Tommasini Grotto, Raul Machado Neto, Dimas Tadeu Covas, Sandra Coccuzzo Sampaio, Maria Carolina Elias, Jayme A. Souza-Neto
Summary: This study provides a retrospective overview of the COVID-19 epidemic in Sao Paulo City, Brazil, by analyzing near-complete genome sequences. The analysis reveals multiple independent introduction events of different variants and identifies the viral movement within different regions. The results emphasize the importance of increasing genomic monitoring to track the real-time evolution of the virus and detect any potential emergence of new variants of concern.
Article
Virology
Anielly S. da Silva, Gabriel Montenegro de Campos, Marta Giovanetti, Victoria Simonatto Zucherato, Alex Ranieri Jeronimo Lima, Elaine Vieira Santos, Rodrigo Haddad, Massimo Ciccozzi, Luiz Carlos Junior Alcantara, Maria Carolina Elias, Sandra Coccuzzo Sampaio, Dimas Tadeu Covas, Simone Kashima, Svetoslav Nanev Slavov
Summary: In this study, metagenomics was used to identify viral infections among pediatric patients with acute respiratory disease. Two pools of samples were found to contain the little-known Malawi polyomavirus (MWPyV). Further testing revealed that MWPyV-positive samples also tested positive for respiratory syncytial virus. Phylogenetic analysis of MWPyV genome sequences from index samples was conducted, providing insights into its viral origin. This study represents the first molecular and genomic characterization of MWPyV in pediatric patients in South America.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Article
Virology
Cynthia Vazquez, Luiz Carlos Junior Alcantara, Vagner Fonseca, Mauricio Lima, Joilson Xavier, Talita Adelino, Hegger Fritsch, Emerson Castro, Carla de Oliveira, Gabriel Schuab, Alex Ranieri Jeronimo Lima, Shirley Villalba, Andrea Gomez de la Fuente, Analia Rojas, Cesar Cantero, Fatima Fleitas, Carolina Aquino, Andrea Ojeda, Guillermo Sequera, Juan Torales, Julio Barrios, Maria Carolina Elias, Felipe C. M. Iani, Maria Jose Ortega, Maria Liz Gamarra, Romeo Montoya, Evandra Strazza Rodrigues, Simone Kashima, Sandra Coccuzzo Sampaio, Norma Coluchi, Juliana Leite, Lionel Gresh, Leticia Franco, Jose Lourenco, Jairo Mendez Rico, Ana Maria Bispo de Filippis, Marta Giovanetti
Summary: Due to the significant threat of dengue virus in Paraguay, further prevention and control measures are necessary. Genomic surveillance reveals the co-circulation of multiple dengue virus serotypes in Paraguay and highlights the possible role of Brazil as a source for international dispersion of different viral strains. This emphasizes the need for increased surveillance across borders.
Article
Oncology
Dalila Luciola Zanette, Karoline Brito Caetano Andrade Coelho, Eneas de Carvalho, Mateus Nobrega Aoki, Jeanine Marie Nardin, Larissa Araujo Lalli, Rafael dos Santos Bezerra, Marta Giovanetti, Victoria Simionatto Zucherato, Gabriel Montenegro de Campos, Jardelina de Souza Todao Bernardino, Vincent Louis Viala, Massimo Ciccozzi, Luiz Carlos Junior Alcantara, Sandra Coccuzzo Sampaio, Maria Carolina Elias, Simone Kashima, Dimas Tadeu Covas, Svetoslav Nanev Slavov
Summary: A study examined the composition of plasma virome in patients with prostate cancer, finding that Anelloviruses and Human Pegivirus-1 (HPgV-1) were the most abundant components. Clinically important viruses like hepatitis C virus (HCV), cytomegalovirus, and human adenovirus type C were also identified. In comparison, the virome of blood donors was mainly composed of torque teno virus types (TTV). This study sheds light on the viral abundance and diversity in patients with prostate cancer, suggesting that malignant processes may influence virome composition.
MOLECULAR & CELLULAR ONCOLOGY
(2023)
Article
Hematology
Victoria Simionatto Zucherato, Marta Giovanetti, Lara Okuyama Afonso Costa, Luciana Maria Fontanari Krause, Daiani Cristina Ciliao Alves, Renata Maria Alencar Moreira, Barbara Maciel Sidou Pimentel, Rodrigo Haddad, Hellen Tayana Bitencourt, Massimo Ciccozzi, Luiz Carlos Alcantara Jr, Simone Kashima, Dimas Tadeu Covas, Svetoslav Nanev Slavov
Summary: This study investigated the prevalence of HuGkV-2 DNA among healthy blood donors from different regions in Brazil. The results showed that the highest prevalence was recorded in the Brazilian Amazon at 15.3%. Although this provides preliminary insights into the impact of this emerging viral agent, further studies are needed to understand the prevalence, transmission routes, and possible clinical effects.
TRANSFUSION AND APHERESIS SCIENCE
(2023)