Sorting nexin 27 interactome in T-lymphocytes identifies zona occludens-2 dynamic redistribution at the immune synapse

The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity

(2016) Rune Busk Damgaard et al.   CELL

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Connexin43 Forms Supramolecular Complexes through Non-Overlapping Binding Sites for Drebrin, Tubulin, and ZO-1

(2016) Cinzia Ambrosi et al.   PLoS One

FAM21 directs SNX27–retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus

(2016) Seongju Lee et al.   Nature Communications

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULIN

(2015) Paul R. Elliott et al.   FEBS Journal

Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation

(2015) Gina J. Fiala et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SNX17 Affects T Cell Activation by Regulating TCR and Integrin Recycling

(2015) Douglas G. Osborne et al.   JOURNAL OF IMMUNOLOGY

USP7 Acts as a Molecular Rheostat to Promote WASH-Dependent Endosomal Protein Recycling and Is Mutated in a Human Neurodevelopmental Disorder

(2015) Yi-Heng Hao et al.   MOLECULAR CELL

Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export

(2015) Andrea Legati et al.   NATURE GENETICS

A defect in the retromer accessory protein, SNX27, manifests by infantile myoclonic epilepsy and neurodegeneration

(2015) Nadirah Damseh et al.   NEUROGENETICS

2016 update of the PRIDE database and its related tools

(2015) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Phosphoinositide binding by the SNX27 FERM domain regulates its localization at the immune synapse of activated T-cells

(2014) R. Ghai et al.   JOURNAL OF CELL SCIENCE

Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling

(2014) I. J. McGough et al.   JOURNAL OF CELL SCIENCE

Sorting Nexin 31 Binds Multiple β Integrin Cytoplasmic Domains and Regulates β1 Integrin Surface Levels and Stability

(2014) Hui-Yuan Tseng et al.   JOURNAL OF MOLECULAR BIOLOGY

A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer

(2014) M. Gallon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for sorting nexin 27 in AMPA receptor trafficking

(2014) Li Shen Loo et al.   Nature Communications

Sorting Nexin 27 Regulates Aβ Production through Modulating γ-Secretase Activity

(2014) Xin Wang et al.   Cell Reports

Sorting nexin 27 (SNX27) associates with zonula occludens-2 (ZO-2) and modulates the epithelial tight junction

(2013) Seth P. Zimmerman et al.   BIOCHEMICAL JOURNAL

DNAJC13 mutations in Parkinson disease

(2013) Carles Vilariño-Güell et al.   HUMAN MOLECULAR GENETICS

Kidins220/ARMS Associates with B-Raf and the TCR, Promoting Sustained Erk Signaling in T Cells

(2013) S. Deswal et al.   JOURNAL OF IMMUNOLOGY

A novel mutation inKIAA0196: identification of a gene involved in Ritscher–Schinzel/3C syndrome in a First Nations cohort

(2013) Alison M Elliott et al.   JOURNAL OF MEDICAL GENETICS

A global analysis of SNX27–retromer assembly and cargo specificity reveals a function in glucose and metal ion transport

(2013) Florian Steinberg et al.   NATURE CELL BIOLOGY

Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome

(2013) Xin Wang et al.   NATURE MEDICINE

Microglial Beclin 1 Regulates Retromer Trafficking and Phagocytosis and Is Impaired in Alzheimer’s Disease

(2013) Kurt M. Lucin et al.   NEURON

Regulation of Dendritic Filopodial Interactions by ZO-1 and Implications for Dendrite Morphogenesis

(2013) Ryouhei Komaki et al.   PLoS One

Citron kinase controls a molecular network required for midbody formation in cytokinesis

(2013) Z. I. Bassi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

(2013) R. Ghai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inorganic Phosphate Export by the Retrovirus Receptor XPR1 in Metazoans

(2013) Donatella Giovannini et al.   Cell Reports

Kidins220 accumulates with tau in human Alzheimer's disease and related models: modulation of its calpain-processing by GSK3β/PP1 imbalance

(2012) Celia López-Menéndez et al.   HUMAN MOLECULAR GENETICS

SNX17 protects integrins from degradation by sorting between lysosomal and recycling pathways

(2012) Florian Steinberg et al.   JOURNAL OF CELL BIOLOGY

Signaling at neuro/immune synapses

(2012) Michael L. Dustin   JOURNAL OF CLINICAL INVESTIGATION

Actin retrograde flow and actomyosin II arc contraction drive receptor cluster dynamics at the immunological synapse in Jurkat T cells

(2012) Jason Yi et al.   MOLECULAR BIOLOGY OF THE CELL

Disruption of Mouse Cenpj, a Regulator of Centriole Biogenesis, Phenocopies Seckel Syndrome

(2012) Rebecca E. McIntyre et al.   PLoS Genetics

VPS35 Mutations in Parkinson Disease

(2011) Carles Vilariño-Güell et al.   AMERICAN JOURNAL OF HUMAN GENETICS

SH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complex

(2011) Lifeng Feng et al.   CELL BIOCHEMISTRY AND FUNCTION

Identification of a novel candidate gene for non-syndromic autosomal recessive intellectual disability: the WASH complex member SWIP

(2011) F. Ropers et al.   HUMAN MOLECULAR GENETICS

Sorting Nexin 27 Protein Regulates Trafficking of a p21-activated Kinase (PAK) Interacting Exchange Factor (β-Pix)-G Protein-coupled Receptor Kinase Interacting Protein (GIT) Complex via a PDZ Domain Interaction

(2011) Julie L. Valdes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Translocation dynamics of sorting nexin 27 in activated T cells

(2011) E. Rincon et al.   JOURNAL OF CELL SCIENCE

Functional Gap Junctions Accumulate at the Immunological Synapse and Contribute to T Cell Activation

(2011) A. Mendoza-Naranjo et al.   JOURNAL OF IMMUNOLOGY

Deficiency of Sorting Nexin 27 (SNX27) Leads to Growth Retardation and Elevated Levels of N-Methyl-D-Aspartate Receptor 2C (NR2C)

(2011) L. Cai et al.   MOLECULAR AND CELLULAR BIOLOGY

Diacylglycerol kinase ζ controls diacylglycerol metabolism at the immunological synapse

(2011) Severine I. Gharbi et al.   MOLECULAR BIOLOGY OF THE CELL

SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors

(2011) Paul Temkin et al.   NATURE CELL BIOLOGY

Mechanism underlying selective regulation of G protein-gated inwardly rectifying potassium channels by the psychostimulant-sensitive sorting nexin 27

(2011) B. Balana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling

(2010) Tsutomu Oka et al.   BIOCHEMICAL JOURNAL

SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane

(2010) Benjamin E.L. Lauffer et al.   JOURNAL OF CELL BIOLOGY

F-actin-binding protein drebrin regulates CXCR4 recruitment to the immune synapse

(2010) M. Perez-Martinez et al.   JOURNAL OF CELL SCIENCE

Zonula Occludens-1 and -2 Are Cytosolic Scaffolds That Regulate the Assembly of Cellular Junctions

(2009) Alan S. Fanning et al.   Annals of the New York Academy of Sciences

Connexins: a myriad of functions extending beyond assembly of gap junction channels

(2009) Hashem A Dbouk et al.   Cell Communication and Signaling

A FAM21-Containing WASH Complex Regulates Retromer-Dependent Sorting

(2009) Timothy S. Gomez et al.   DEVELOPMENTAL CELL

Gap Junctions at the Dendritic Cell-T Cell Interface Are Key Elements for Antigen-Dependent T Cell Activation

(2009) R. Elgueta et al.   JOURNAL OF IMMUNOLOGY

CPAP is a cell-cycle regulated protein that controls centriole length

(2009) Chieh-Ju C. Tang et al.   NATURE CELL BIOLOGY

Lifeact: a versatile marker to visualize F-actin

(2008) Julia Riedl et al.   NATURE METHODS

Endosomal sorting and signalling: an emerging role for sorting nexins

(2008) Peter J. Cullen   NATURE REVIEWS MOLECULAR CELL BIOLOGY