Urban fine particulate matter (PM2.5) exposure destroys blood–testis barrier (BTB) integrity through excessive ROS-mediated autophagy

Exposure scenario: Another important factor determining the toxic effects of PM2.5 and possible mechanisms involved

(2017) Wei Zhou et al.   ENVIRONMENTAL POLLUTION

Allergic disease associations with regional and localized estimates of air pollution

(2017) Amy A. Schultz et al.   ENVIRONMENTAL RESEARCH

Socioeconomic and air pollution correlates of adult asthma, heart attack, and stroke risks in the United States, 2010–2013

(2017) Louis Anthony (Tony) Cox et al.   ENVIRONMENTAL RESEARCH

Benzo[a]pyrene-7,8-diol-9,10-epoxide suppresses the migration and invasion of human extravillous trophoblast HTR-8/SVneo cells by down-regulating MMP2 through inhibition of FAK/SRC/PI3K/AKT pathway

(2017) Rong Wang et al.   TOXICOLOGY

Involvement of oxidative stress and calcium signaling in airborne particulate matter - induced damages in human pulmonary artery endothelial cells

(2017) J. Deweirdt et al.   TOXICOLOGY IN VITRO

Urban fine particulate matter exposure causes male reproductive injury through destroying blood-testis barrier (BTB) integrity

(2017) Xi-ning Cao et al.   TOXICOLOGY LETTERS

Protective effects of vitamin E against reproductive toxicity induced by di(2-ethylhexyl) phthalate via PPAR-dependent mechanisms

(2017) Yangcai Wang et al.   TOXICOLOGY MECHANISMS AND METHODS

Protective effects of vitamin E against reproductive toxicity induced by di(2-ethylhexyl) phthalate via PPAR-dependent mechanisms

(2017) Yangcai Wang et al.   TOXICOLOGY MECHANISMS AND METHODS

Induction of reactive oxygen species-stimulated distinctive autophagy by chelerythrine in non-small cell lung cancer cells

(2017) Zheng-Hai Tang et al.   Redox Biology

Vitamin C and vitamin E supplementation alleviates oxidative stress induced by dexamethasone and improves fertility of breeder roosters

(2016) Yuna Min et al.   ANIMAL REPRODUCTION SCIENCE

TP53-dependent autophagy links the ATR-CHEK1 axis activation to proinflammatory VEGFA production in human bronchial epithelial cells exposed to fine particulate matter (PM2.5)

(2016) Xiuduan Xu et al.   Autophagy

Amelioration of particulate matter-induced oxidative damage by vitamin c and quercetin in human bronchial epithelial cells

(2016) Xiaoting Jin et al.   CHEMOSPHERE

Gene expression network analyses in response to air pollution exposures in the trucking industry

(2016) Jen-hwa Chu et al.   Environmental Health

Association between air pollution and sperm quality: A systematic review and meta-analysis

(2016) Zibing Deng et al.   ENVIRONMENTAL POLLUTION

Redox regulation of autophagy in skeletal muscle

(2016) George G. Rodney et al.   FREE RADICAL BIOLOGY AND MEDICINE

Bayesian multinomial probit modeling of daily windows of susceptibility for maternal PM2.5 exposure and congenital heart defects

(2016) Joshua L. Warren et al.   STATISTICS IN MEDICINE

The Role of Autophagy in the Maintenance of Stemness and Differentiation of Mesenchymal Stem Cells

(2016) Francesca Vittoria Sbrana et al.   Stem Cell Reviews and Reports

Repeated PM2.5 exposure inhibits BEAS-2B cell P53 expression through ROS-Akt-DNMT3B pathway-mediated promoter hypermethylation

(2016) Wei Zhou et al.   Oncotarget

The Role of Autophagy in the Maintenance of Stemness and Differentiation of Mesenchymal Stem Cells

(2016) Francesca Vittoria Sbrana et al.   Stem Cell Reviews and Reports

Chemical exposure-response relationship between air pollutants and reactive oxygen species in the human respiratory tract

(2016) Pascale S. J. Lakey et al.   Scientific Reports

Overproduction of reactive oxygen species and activation of MAPKs are involved in apoptosis induced by PM2.5in rat cardiac H9c2 cells

(2015) Jing Cao et al.   JOURNAL OF APPLIED TOXICOLOGY

Fine particulate matter leads to reproductive impairment in male rats by overexpressing phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway

(2015) Xi-ning Cao et al.   TOXICOLOGY LETTERS

TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations

(2015) Fang Hua et al.   Nature Communications

Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death

(2014) P Makhov et al.   BRITISH JOURNAL OF CANCER

The cell–cell junctions of mammalian testes: I. The adhering junctions of the seminiferous epithelium represent special differentiation structures

(2014) Lisa M. Domke et al.   CELL AND TISSUE RESEARCH

Air pollution and decreased semen quality: A comparative study of Chongqing urban and rural areas

(2014) Niya Zhou et al.   ENVIRONMENTAL POLLUTION

Adult lung function and long-term air pollution exposure. ESCAPE: a multicentre cohort study and meta-analysis

(2014) M. Adam et al.   EUROPEAN RESPIRATORY JOURNAL

Spatial Association Between Ambient Fine Particulate Matter and Incident Hypertension

(2013) Hong Chen et al.   CIRCULATION

Oxidative stress and phthalate-induced down-regulation of steroidogenesis in MA-10 Leydig cells

(2013) Liang Zhou et al.   REPRODUCTIVE TOXICOLOGY

Sertoli Cell Is a Potential Target for Perfluorooctane Sulfonate–Induced Reproductive Dysfunction in Male Mice

(2013) Lianglin Qiu et al.   TOXICOLOGICAL SCIENCES

Programmed cell death pathways in cancer: a review of apoptosis, autophagy and programmed necrosis

(2012) L. Ouyang et al.   CELL PROLIFERATION

Mammalian target of rapamycin: A valid therapeutic target through the autophagy pathway for alzheimer's disease?

(2012) Zhiyou Cai et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The effect of environmental contaminants on testicular function

(2011) Premendu Prakash Mathur et al.   ASIAN JOURNAL OF ANDROLOGY

Autophagy and disease: always two sides to a problem

(2011) Sunandini Sridhar et al.   JOURNAL OF PATHOLOGY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Tolerance of Spermatogonia to Oxidative Stress Is Due to High Levels of Zn and Cu/Zn Superoxide Dismutase

(2011) Fritzie T. Celino et al.   PLoS One

Atg8: an autophagy-related ubiquitin-like protein family

(2011) Tomer Shpilka et al.   GENOME BIOLOGY

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

Zonula Occludens-1 and -2 Are Cytosolic Scaffolds That Regulate the Assembly of Cellular Junctions

(2009) Alan S. Fanning et al.   Annals of the New York Academy of Sciences

Links between Autophagy, Innate Immunity, Inflammation and Crohn’s Disease

(2009) Vojo Deretic   DIGESTIVE DISEASES

The Effect of Ambient Air Pollution on Sperm Quality

(2009) Craig Hansen et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Decreased sperm motility is associated with air pollution in Salt Lake City

(2009) Ahmad Hammoud et al.   FERTILITY AND STERILITY

Regulation of Autophagy by Reactive Oxygen Species (ROS): Implications for Cancer Progression and Treatment

(2008) Meghan B. Azad et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL