The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo

Title
The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo
Authors
Keywords
P-glycoprotein, CYP3A4, Interplay, Selective P-gp inhibitor, Precision-cut intestinal slice, Ex vivo
Journal
TOXICOLOGY IN VITRO
Volume 40, Issue -, Pages 26-33
Publisher
Elsevier BV
Online
2016-12-08
DOI
10.1016/j.tiv.2016.12.002

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