An Evaluation of the Human Relevance of the Lung Tumors Observed in Female Mice Treated With Permethrin Based on Mode of Action

Relationship of Metabolism and Cell Proliferation to the Mode of Action of Fluensulfone-Induced Mouse Lung Tumors. II: Additional Mechanistic Studies

(2016) Christian Strupp et al.   TOXICOLOGICAL SCIENCES

Critical role of toxicologic pathology in a short-term screen for carcinogenicity

(2016) Samuel M. Cohen et al.   Journal of Toxicologic Pathology

Evaluation of the mode of action of mouse lung tumors induced by 4-methylimidazole

(2015) George Cruzan et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Scientific and Regulatory Policy Committee (SRPC) Review*

(2015) Charles E. Wood et al.   TOXICOLOGIC PATHOLOGY

Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study

(2013) J. Christopher Corton et al.   CRITICAL REVIEWS IN TOXICOLOGY

Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator

(2013) Clifford R. Elcombe et al.   CRITICAL REVIEWS IN TOXICOLOGY

Relationship of Metabolism and Cell Proliferation to the Mode of Action of Fluensulfone-Induced Mouse Lung Tumors: Analysis of Their Human Relevance Using the IPCS Framework

(2012) Christian Strupp et al.   TOXICOLOGICAL SCIENCES

CYP2F2-generated metabolites, not styrene oxide, are a key event mediating the mode of action of styrene-induced mouse lung tumors

(2011) G. Cruzan et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Chemical Carcinogenesis

(2010) S. M. Cohen et al.   TOXICOLOGICAL SCIENCES

Expression profiles of thioredoxin family proteins in human lung cancer tissue: correlation with proliferation and differentiation

(2009) Aristi P Fernandes et al.   HISTOPATHOLOGY

Mouse specific lung tumors from CYP2F2-mediated cytotoxic metabolism: An endpoint/toxic response where data from multiple chemicals converge to support a mode of action

(2009) George Cruzan et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

IPCS Framework for Analyzing the Relevance of a Noncancer Mode of Action for Humans

(2008) Alan R. Boobis et al.   CRITICAL REVIEWS IN TOXICOLOGY

Cancer Incidence among Pesticide Applicators Exposed to Permethrin in the Agricultural Health Study

(2008) Jennifer A. Rusiecki et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Mechanism of Ethylbenzene-Induced Mouse-Specific Lung Tumor: Metabolism of Ethylbenzene by Rat, Mouse, and Human Liver and Lung Microsomes

(2008) Shakil A. Saghir et al.   TOXICOLOGICAL SCIENCES

Critical appraisal of the expression of cytochrome P450 enzymes in human lung and evaluation of the possibility that such expression provides evidence of potential styrene tumorigenicity in humans

(2008) Gary P. Carlson   TOXICOLOGY