Arsenite Induces Vascular Endothelial Cell Dysfunction by Activating IRE1α/XBP1s/HIF1α-Dependent ANGII Signaling

ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction underlie apoptosis induced by resveratrol and arsenic trioxide in A549 cells

(2016) Shiyan Gu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Candesartan ameliorates arsenic-induced hypertensive vascular remodeling by regularizing angiotensin II and TGF-beta signaling in rats

(2016) Maibam Wanta Khuman et al.   TOXICOLOGY

Endoplasmic Reticulum Stress in Immunity

(2015) Sarah E. Bettigole et al.   Annual Review of Immunology

Arsenic trioxide induces programmed cell death through stimulation of ER stress and inhibition of the ubiquitin–proteasome system in human sarcoma cells

(2015) Hui-Wen Chiu et al.   CANCER LETTERS

Arsenic causes aortic dysfunction and systemic hypertension in rats: Augmentation of angiotensin II signaling

(2015) Prashantkumar Waghe et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Hypertension: Renin-Angiotensin-Aldosterone System Alterations

(2015) L. te Riet et al.   CIRCULATION RESEARCH

The mechanistic basis of arsenicosis: Pathogenesis of skin cancer

(2014) Katherine M. Hunt et al.   CANCER LETTERS

Novel Mechanism of Blood Pressure Regulation By Forkhead Box Class O1–Mediated Transcriptional Control of Hepatic Angiotensinogen

(2014) Yajuan Qi et al.   HYPERTENSION

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

(2014) Xi Chen et al.   NATURE

Atorvastatin ameliorates arsenic-induced hypertension and enhancement of vascular redox signaling in rats

(2014) Thengumpallil Sasindran Sarath et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Atorvastatin restores arsenic-induced vascular dysfunction in rats: Modulation of nitric oxide signaling and inflammatory mediators

(2014) Manickam Kesavan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Vascular Endothelial Cell Growth–Activated XBP1 Splicing in Endothelial Cells Is Crucial for Angiogenesis

(2013) Lingfang Zeng et al.   CIRCULATION

Cardiovascular effects of arsenic: clinical and epidemiological findings

(2013) Francesco Stea et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Molecular features in arsenic-induced lung tumors

(2013) Roland Hubaux et al.   Molecular Cancer

Interleukin-6 Mediates Angiotensinogen Gene Expression during Liver Regeneration

(2013) Hong-Shiee Lai et al.   PLoS One

Arsenic toxicity induced endothelial dysfunction and dementia: Pharmacological interdiction by histone deacetylase and inducible nitric oxide synthase inhibitors

(2013) Bhupesh Sharma et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Arsenic upregulates the expression of angiotensin II Type I receptor in mouse aortic endothelial cells

(2013) Ekhtear Hossain et al.   TOXICOLOGY LETTERS

Gene Trapping Uncovers Sex-Specific Mechanisms for Upstream Stimulatory Factors 1 and 2 in Angiotensinogen Expression

(2012) Sungmi Park et al.   HYPERTENSION

XBP1mRNA Splicing Triggers an Autophagic Response in Endothelial Cells throughBECLIN-1Transcriptional Activation

(2012) Andriana Margariti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IKKα contributes to UVB-induced VEGF expression by regulating AP-1 transactivation

(2011) Wen Dong et al.   NUCLEIC ACIDS RESEARCH

Arsenic trioxide induces endoplasmic reticulum stress-related events in neutrophils

(2010) François Binet et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Arsenic Exposure and Cardiovascular Disorders: An Overview

(2009) Pitchai Balakumar et al.   Cardiovascular Toxicology

Synergistic co-operation of signal transducer and activator of transcription 5B with activator protein 1 in angiotensin II-induced angiotensinogen gene activation in vascular smooth muscle cells

(2009) Mei Han et al.   FEBS Journal

Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow

(2009) L. Zeng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arsenic and Cardiovascular Disease

(2008) J. Christopher States et al.   TOXICOLOGICAL SCIENCES