Article
Surgery
Stefan Wallen, Gustaf Bruze, Johan Ottosson, Claude Marcus, Johan Sundstrom, Eva Szabo, Torsten Olbers, Maria Palmetun-Ekback, Ingmar Naslund, Martin Neovius
Summary: This study aimed to compare the use of opioids in patients with obesity who underwent bariatric surgery versus those who underwent intensive lifestyle modification. The results showed that patients who underwent bariatric surgery had a higher proportion of opioid users and a larger total opioid dose, especially in those who received additional surgery during follow-up.
Article
Multidisciplinary Sciences
Suk Bae Moon, Sung Jin Hwang, Sal Baker, Minkyung Kim, Kent Sasse, Sang Don Koh, Kenton M. Sanders, Sean M. Ward
Summary: Obesity is a critical risk factor for life-threatening diseases, and the prevalence in adults has significantly increased in the past decade. Surgical treatment, such as sleeve gastrectomy, is the most effective method for obese patients. However, the changes in gastric wall cells and pacemaker activity after surgery, as well as the recovery of normal gastric activity, require further investigation.
Article
Surgery
David E. Arterburn, Eric Johnson, Karen J. Coleman, Lisa J. Herrinton, Anita P. Courcoulas, David Fisher, Robert A. Li, Mary Kay Theis, Liyan Liu, James R. Fraser, Sebastien Haneuse
Summary: Among patients with severe obesity undergoing SG and RYGB, significantly more weight loss was observed at 5 years compared to nonsurgical patients. Weight regain was common after surgery, but regain to within 5% of baseline was rare.
Article
Medicine, General & Internal
Gerardo Sarno, Pietro Calabrese, Salvatore Tramontano, Luigi Schiavo, Vincenzo Pilone
Summary: Sleeve gastrectomy is the most common weight loss surgery for severe obesity, but complications like leakages and strictures can occur. Gastric twist is a rare complication, which is a functional obstruction of the gastric remnant likely caused by technical mistakes. Endoscopy is the first choice for diagnosis and treatment, but surgery is necessary if endoscopy fails.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Nutrition & Dietetics
Jan O. Aaseth, Jan Alexander
Summary: Obesity is a worldwide epidemic with adverse health effects, leading to increased use of bariatric surgery such as sleeve gastrectomy (SG) and Roux-en-Y-gastric bypass (RYGB). This review focuses on postoperative osteoporosis risk and micronutrient deficiencies associated with RYGB and SG. Dietary habits in obese individuals may contribute to deficiencies in vitamin D and other nutrients affecting bone metabolism. Both surgical procedures have different impacts on nutrient absorption, with SG affecting vitamin B-12 and D absorption, while RYGB affects fat-soluble vitamins. Regular follow-ups and nutritional advice are crucial to prevent osteoporosis and other postoperative issues.
Article
Surgery
Karan R. Chhabra, Dana A. Telem, Grace F. Chao, David E. Arterburn, Jie Yang, Jyothi R. Thumma, Andrew M. Ryan, Blanche Blumenthal, Justin B. Dimick
Summary: In a large cohort of commercially insured patients, sleeve gastrectomy was found to have a superior safety profile to gastric bypass up to 2 years from surgery, even when accounting for selection bias. However, further exploration is needed regarding the higher risk of revisions in sleeve gastrectomy.
Article
Surgery
Jeremy Jen, Hau Phan, Brett Johnson, Corliann Blyn, Janet Lavrich, Krishna Mallem, Priya Kalsank Pai, Piotr Krecioch
Summary: Revisional surgery to convert sleeve gastrectomy (SG) to either Roux-en-Y gastric bypass (RYGB) or duodenal switch (DS) can lead to significant and sustained weight loss in the first 12 months. There was no significant difference in excess body weight loss between RYGB and DS patients at 6, 12, and 24 months, except for greater weight loss in RYGB patients at 3 months. Procedure length was significantly longer for DS compared to RYGB, with no significant differences in length of stay and 30-day readmission rates.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Gastroenterology & Hepatology
Andreas Plamper, Philipp Lingohr, Jennifer Nadal, Jonel Trebicka, Maximilian J. Brol, Anna Woestemeier, Sophia M-T Schmitz, Patrick H. Alizai, Ulf P. Neumann, Tom F. Ulmer, Karl P. Rheinwalt
Summary: This study compared the long-term outcomes of one anastomosis gastric bypass (OAGB) and sleeve gastrectomy (SG) in bariatric surgery patients. The results showed that OAGB had superior effects on weight loss, improvement of type 2 diabetes and sleep apnea, while SG was associated with more long-term problems such as insufficient weight loss/regain and reflux. However, OAGB had a higher risk of nutritional deficiencies.
JOURNAL OF GASTROINTESTINAL SURGERY
(2023)
Article
Surgery
Camille Marciniak, Xavier Lenne, Amelie Bruandet, Aghiles Hamroun, Michael Genin, Gregory Baud, Didier Theis, Francois Pattou, Robert Caiazzo
Summary: This study assessed the relevance of concomitant laparoscopic metabolic bariatric surgery (MBS) and cholecystectomy, and found that cholecystectomy should be avoided during sleeve gastrectomy (SG) and gastric bypass (GBP) procedures. Prophylactic cholecystectomy is not recommended for asymptomatic gallstones after MBS.
Article
Surgery
Kelly G. H. van de Pas, Danielle S. Bonouvrie, Loes Janssen, Marleen M. Romeijn, Arijan A. P. M. Luijten, Wouter K. G. Leclercq, Francois M. H. van Dielen
Summary: This study compared weight loss outcomes between Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in young adults and found that RYGB resulted in greater weight loss in the short- and midterm, particularly in females.
Article
Surgery
Brigitte Anderson, Tingting Zhan, Luke Swaszek, Caroline Sanicola, Neil King, Aurora Pryor, Konstantinos Spaniolas, Renee Tholey, Francesco Palazzo, Alec Beekley, Talar Tatarian
Summary: This study evaluated the incidence of marginal ulcers (MUs) after primary and secondary Roux-en-Y Gastric Bypass (RYGB). The results showed that patients who underwent conversion of Sleeve Gastrectomy to RYGB had a higher incidence of MUs compared to those who had primary RYGB or Gastric Banding to RYGB. Furthermore, the time to MU development was significantly shorter in patients who underwent conversion surgery.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Surgery
Spyridon Kapoulas, Mohamed Sahloul, Rishi Singhal
Summary: The most common indication for revisional surgery after sleeve gastrectomy is weight loss failure. Options for revisional surgery include RYGB, OAGB, and re-sleeve, but there are higher complication rates following revisional surgery. The efficacy of re-operation in terms of weight loss and morbidity reduction is still debated due to the lack of high-quality evidence in the field.
Article
Gastroenterology & Hepatology
Jessica X. Yu, Russell D. Dolan, Sean Bhalla, Laura Mazer, Lydia Watts, Allison R. Schulman
Summary: Sleeve gastrectomy is a commonly performed bariatric surgery, with rising prevalence of gastric sleeve stenosis (GSS). Management with pneumatic dilation is successful but underused due to lack of diagnostic criteria. This study aimed to develop quantifiable endoscopic criteria for GSS diagnosis, finding an association between narrowest to widest gastric lumen diameter ratio and presence of bilious fluid with EndoFLIP and gastric lumen morphology diagnosis. Further studies are needed to validate these criteria.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Surgery
Mojgan Nazari, Carolyn Jameson, Brendan Ryan, Anthony Brancatisano
Summary: This study compared the safety and efficacy of sleeve gastrectomy (SG) and one anastomosis gastric bypass (OAGB) as conversion surgical procedures for patients who had adjustable gastric band (LAGB) and experienced suboptimal response or weight recurrence. The results showed that both procedures resulted in significant weight loss and similar remission of comorbidities, but OAGB had a higher complication rate compared to SG.
Article
Surgery
Panagiotis Drakos, Panagiotis Volteas, Alisa Khomutova, Jie Yang, Lizhou Nie, Aurora D. Pryor, Salvatore Docimo, Kinga A. Powers, Konstantinos Spaniolas
Summary: Revisional sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) have better long-term durability compared to primary surgery in terms of revision or conversion.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Article
Endocrinology & Metabolism
John P. Kirwan, Christopher L. Axelrod, Emily L. Kullman, Steven K. Malin, Wagner S. Dantas, Kathryn Pergola, Juan Pablo del Rincon, Stacy A. Brethauer, Sangeeta R. Kashyap, Philip R. Schauer
Summary: The study showed that patients with type 2 diabetes undergoing Roux-en-Y gastric bypass (RYGB) surgery experienced significant reductions in body weight, fat mass, fasting glucose and insulin levels, and circulating lipids 2 weeks post-operation. Oral feeding enhanced insulin and incretin secretion after RYGB, while G-tube feeding completely abolished this enhancement, suggesting that foregut exclusion plays a role in improving glucose metabolism after RYGB, but may not be the sole explanation.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Surgery
Ali Aminian, Sangeeta R. Kashyap, Kathy E. Wolski, Stacy A. Brethauer, John P. Kirwan, Steven E. Nissen, Deepak L. Bhatt, Philip R. Schauer
Summary: This study found that metabolic surgery in patients with T2DM is associated with long-term favorable changes in certain patient-reported outcomes compared with intensive medical therapy, particularly in physical health and diabetes-related domains. The effects on psychosocial well-being were similar among the study groups.
Article
Endocrinology & Metabolism
Ali Aminian, Rickesha Wilson, Alexander Zajichek, Chao Tu, Kathy E. Wolski, Philip R. Schauer, Michael W. Kattan, Steven E. Nissen, Stacy A. Brethauer
Summary: The study findings suggest that in patients with obesity and type 2 diabetes mellitus, Roux-en-Y gastric bypass (RYGB) surgery may be associated with greater weight loss, better diabetes control, and lower risk of major adverse cardiovascular events (MACE) and nephropathy compared with sleeve gastrectomy (SG) surgery.
Article
Peripheral Vascular Disease
Michael E. Hall, Jordana B. Cohen, Jamy D. Ard, Brent M. Egan, John E. Hall, Carl J. Lavie, Jun Ma, Chiadi E. Ndumele, Philip R. Schauer, Daichi Shimbo
Summary: Obesity is a major risk factor for primary hypertension, and lifestyle modification is usually recommended for obese patients, but long-term success is limited.
Article
Endocrinology & Metabolism
Matthew C. Riddle, William T. Cefalu, Philip H. Evans, Hertzel C. Gerstein, Michael A. Nauck, William K. Oh, Amy E. Rothberg, Carel W. le Roux, Francesco Rubino, Philip Schauer, Roy Taylor, Douglas Twenefour
Summary: Improvement of glucose levels in people with diabetes can occur spontaneously or after medical interventions. Newer forms of treatment may lead to more sustained improvement. However, the terminology and objective measures for defining this process are not established, and the long-term risks and benefits are not well understood. An international expert group proposed the term "remission" and HbA1c < 6.5% as the usual diagnostic criterion. They also suggested active observation and further research on predictors and outcomes of remission.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Medicine, General & Internal
Ali Aminian, Abbas Al-Kurd, Rickesha Wilson, James Bena, Hana Fayazzadeh, Tavankit Singh, Vance L. Albaugh, Faiz U. Shariff, Noe A. Rodriguez, Jian Jin, Stacy A. Brethauer, Srinivasan Dasarathy, Naim Alkhouri, Philip R. Schauer, Arthur J. McCullough, Steven E. Nissen
Summary: Among patients with NASH and obesity, bariatric surgery was associated with a significantly lower risk of incident major adverse liver outcomes and MACE compared with nonsurgical management.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Letter
Cardiac & Cardiovascular Systems
Saeed Shoar
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Editorial Material
Surgery
Paulina Salminen, Gerhard Prager, Phil R. Schauer
Article
Surgery
Kerry A. Swanson, Jessica C. Heard, Zhamak Khorgami, C. Anthony Howard, Baddr A. Shakhsheer, Geoffrey S. Chow
Summary: This study examines student perceptions of preparedness for the operating room, resource usage, and time spent on preparation. The results indicate that students feel adequately prepared for discussing operative indications, contraindications, anatomy, and complications but less prepared for operative steps. The average preparation time per case was 28 minutes, with UpToDate and online videos being the most commonly used resources. The use of an anatomic atlas was weakly correlated with improved preparedness for discussing relevant anatomy. Other resources, time spent, or number of resources used were not associated with increased preparedness. The findings suggest a need for improved student-oriented preparatory materials that take into account students' preferences for technology-based resources and time constraints.
SURGEON-JOURNAL OF THE ROYAL COLLEGES OF SURGEONS OF EDINBURGH AND IRELAND
(2023)
Article
Surgery
Ali Esparham, Samira Roohi, Soheil Ahmadyar, Amin Dalili, Peter R. Nelson, Zhamak Khorgami
Summary: This study evaluated the effect of bariatric surgery on markers of arterial damage and dysfunction in patients with obesity. The meta-analysis results showed a significant reduction in CIMT and an increase in FMD and NMD markers after bariatric surgery, indicating an improvement in cardiovascular risk for obese patients.
SURGERY FOR OBESITY AND RELATED DISEASES
(2023)
Review
Medicine, General & Internal
Saeed Shoar, Calvin D. Dao, Noel M. Higgason, Nasrin Shoar
Summary: HIV infection is a known risk factor for cardiovascular diseases. This study aims to estimate the prevalence of myocardial fibrosis (MF) among people living with HIV (PLWH) and determine the factors associated with higher odds of MF development compared with HIV-negative population. The results will be published in a peer-reviewed medical journal.
Review
Surgery
Ali Esparham, Samira Roohi, Soheil Ahmadyar, Amin Dalili, Hengameh Anari Moghadam, Antonio Jose Torres, Zhamak Khorgami
Summary: This systematic review aimed to investigate the mid- and long-term results of duodeno-ileostomy with sleeve gastrectomy (SADI-S). The results showed that SADI-S is a safe and effective surgical technique with durable weight loss and a high rate of comorbidity resolution.
Review
Surgery
Ali Esparham, Ali Mehri, Hooman Hadian, Maryam Taheri, Hengameh Anari Moghadam, Armin Kalantari, Michael J. Fogli, Zhamak Khorgami
Summary: The study evaluated the effect of bariatric metabolic surgery on patients with heart failure and found that it significantly improved left ventricular function and reduced symptoms.
Review
Surgery
Ali Esparham, Soheil Ahmadyar, Tooraj Zandbaf, Amin Dalili, Alireza Rezapanah, Robert Rutledge, Zhamak Khorgami
Summary: This systematic review and meta-analysis found that the incidence of new-onset gastroesophageal reflux after one-anastomosis gastric bypass (OAGB) was 6%. There was no significant change in the preoperative reflux status after OAGB. The rates of esophagitis and Barrett's esophagus were 15% and 1% respectively. The rate of new-onset reflux after OAGB was higher than gastric bypass but not different from sleeve gastrectomy.
Review
Respiratory System
Saeed Shoar, Adriana C. Carolina Prada-Ruiz, Gabriel Patarroyo-Aponte, Ashok Chaudhary, Mohammad Sadegh Asadi
Summary: Heart transplant recipients have a weaker immune response to SARS-CoV-2 vaccination compared to the general population, with older age, the use of anti-metabolite agents such as mycophenolate mofetil, and vaccination during the first year following the transplant identified as potential determinants of a poor immune response.
CLINICAL MEDICINE INSIGHTS-CIRCULATORY RESPIRATORY AND PULMONARY MEDICINE
(2022)