Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase

Published 2017 View Full Article

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Title
Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase
Authors
Keywords
nitroreductase, flavoenzyme, structure, prodrug activation, remediation, isotope effects, substrate binding mode
Journal
STRUCTURE
Volume 25, Issue 7, Pages 978-987.e4
Publisher
Elsevier BV
Online
2017-06-02
DOI
10.1016/j.str.2017.05.002

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