Dual Site Phosphorylation of Caspase-7 by PAK2 Blocks Apoptotic Activity by Two Distinct Mechanisms

Published 2017 View Full Article

Authors

Keywords

apoptosis, cysteine protease, kinase, caspase, prodomain, phosphorylation-mediated inhibition, phosphorylation, kinase-caspase interaction, steric block at active site, phosphomimetic

Journal

STRUCTURE

Volume 25, Issue 1, Pages 27-39

Publisher

Elsevier BV

Online

2016-11-24

DOI

10.1016/j.str.2016.11.001

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