Achieving a Graded Immune Response: BTK Adopts a Range of Active/Inactive Conformations Dictated by Multiple Interdomain Contacts

Published 2017 View Full Article

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Title
Achieving a Graded Immune Response: BTK Adopts a Range of Active/Inactive Conformations Dictated by Multiple Interdomain Contacts
Authors
Keywords
BTK, TEC, kinase regulation, autoinhibition, crystallization-resistant proteins, conformational equilibria
Journal
STRUCTURE
Volume 25, Issue 10, Pages 1481-1494.e4
Publisher
Elsevier BV
Online
2017-09-01
DOI
10.1016/j.str.2017.07.014

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