Computational Modeling Reveals that Signaling Lipids Modulate the Orientation of K-Ras4A at the Membrane Reflecting Protein Topology

Published 2017 View Full Article

Authors

Keywords

Ras GTPase, K-Ras4A, signaling lipids, molecular dynamics simulation, protein topology, protein-membrane interaction, protein complex orientation, anionic lipid, PIP2

Journal

STRUCTURE

Volume 25, Issue 4, Pages 679-689.e2

Publisher

Elsevier BV

Online

2017-03-10

DOI

10.1016/j.str.2017.02.007

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