Article
Surgery
Flavio Roberto Takeda, Marcus Fernando Kodama Pertille Ramos, Marina Alessandra Pereira, Renan Rosetti Muniz, Francisco Tustumi, Tiago Biachi de Castria, Rubens Antonio Aissar Sallum, Bruno Zilberstein, Ulysses Ribeiro Junior, Ivan Cecconello
Summary: In a study of 188 patients undergoing surgical resection for AEGJ, recurrence was observed in 38.3% of patients, with locoregional recurrence accounting for 23.6%, peritoneal recurrence for 27.8%, and distant metastasis for 48.6%. Tumors larger than 5 cm were identified as a risk factor for peritoneal recurrence, while lymph node metastasis was associated with distant recurrence.
AMERICAN JOURNAL OF SURGERY
(2021)
Article
Oncology
Adil Dinia, Samy Ammari, John Filtes, Marion Classe, Antoine Moya-Plana, Francois Bidault, Stephane Temam, Pierre Blanchard, Nathalie Lassau, Philippe Gorphe
Summary: A predictive machine learning model was developed to identify HPV-positive oropharyngeal carcinoma patients at high risk of relapse or death post-treatment. The best model accurately predicted the 5-year risk of relapse-free survival, with a significant difference in relapse-free survival rates between high-risk and low-risk patients.
EUROPEAN JOURNAL OF CANCER
(2022)
Review
Oncology
Lei Wu, Juan Liu, Long Liang, Mian Mao, Xiangpan Li, Tao Li, Jinyi Lang, Qifeng Wang
Summary: This article reports two cases of EGJ carcinoma patients who were treated with a new approach combining immunotherapy and chemotherapy. The treatment showed positive outcomes in terms of extended overall survival and improved quality of life. The combination of immunotherapy and chemoradiotherapy may be a viable option for treating selected EGJ carcinoma patients.
FRONTIERS IN ONCOLOGY
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Tae-Hyung Kim, Jeong Min Lee, Dong Ho Lee, Ijin Joo, Sae-Jin Park, Jung Hee Yoon
Summary: This study compared the local tumor progression (LTP) of percutaneous no-touch radiofrequency ablation (NtRFA) with conventional radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) <= 5 cm through a systematic review and meta-analysis. The results showed that NtRFA had a lower LTP rate of 6% compared to conventional RFA.
EUROPEAN RADIOLOGY
(2023)
Review
Oncology
Tiuri E. Kroese, Hanneke W. M. Van Laarhoven, Magnus Nilsson, Florian Lordick, Matthias Guckenberger, Jelle P. Ruurda, Domenico D'Ugo, Karin Haustermans, Eric Van Cutsem, Richard Van Hillegersberg, Peter S. N. Van Rossum
Summary: Local treatment may improve overall survival in patients with esophagogastric cancer and oligometastatic disease (OMD). The current literature defines OMD as the presence of metastases limited to one organ with no more than three lesions and the presence of an extra-regional lymph node station. Local treatment appears to be associated with improved OS compared to systemic therapy alone.
EUROPEAN JOURNAL OF CANCER
(2022)
Article
Urology & Nephrology
Esther W. C. Lee, Luca Antonelli, Allaudin Issa, James Churchill, Ashwin Sachdeva, Pedro Oliveira, Maurice Lau, Vijay Sangar, Arie Parnham, Christian D. Fankhauser
Summary: This study aimed to investigate the risk of local recurrence in men with no penile cancer but the precancerous lesion penile intraepithelial neoplasia at the surgical margin. The results showed that men with penile intraepithelial neoplasia-positive surgical margins had a higher risk of local recurrence compared to those with completely negative surgical margins.
JOURNAL OF UROLOGY
(2023)
Article
Surgery
Kohei Tanigawa, Shingo Kanaji, Ryuichiro Sawada, Hitoshi Harada, Naoki Urakawa, Hironobu Goto, Hiroshi Hasegawa, Kimihiro Yamashita, Takeru Matsuda, Taro Oshikiri, Yoshihiro Kakeji
Summary: Laparoscopic local resection for GISTs near EGJ, except for those located directly on EGJ, is safe with few postoperative complications and low risk of recurrence.
Article
Oncology
Hui Li, Zhihu Liu, Cuiping Han
Summary: This study investigated the feasibility of surgical resection combined with prophylactic transcatheter arterial chemoembolization (TACE) in reducing the recurrence and improving the survival rate of patients with hepatocellular carcinoma (HCC). The results showed that prophylactic TACE significantly reduced the postoperative recurrence rate and improved the survival rate of patients with HCC. The optimal treatment efficacy was associated with interventional therapy within 1-2 months after surgery, while incomplete envelope, tumor diameter >= 5 cm, and combined cirrhosis were the high-risk factors for HCC recurrence.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2022)
Article
Oncology
Sophia Waldenstedt, Eva Haglind, Eva Angenete
Summary: This study aimed to investigate the symptoms and diagnostic methods of local recurrence in patients after rectal cancer surgery, and found that pain was a common alarm symptom for local recurrence. The majority of patients with local recurrence were diagnosed outside of scheduled follow-ups.
Article
Oncology
Tiuri E. Kroese, George S. Buijs, Matthijs D. L. Burger, Jelle P. Ruurda, Stella Mook, Lodewijk A. A. Brosens, Peter S. N. van Rossum, Richard van Hillegersberg
Summary: This study suggests that for oligometastatic esophagogastric cancer, local plus systemic therapy is associated with improved overall survival (OS) and better OS compared to systemic therapy or local treatment.
ANNALS OF SURGICAL ONCOLOGY
(2022)
Article
Oncology
Chun Chen, Lei Hang, Yupeng Liu, Jin Xie, Jun Yang
Summary: Postcricoid carcinoma is a rare and aggressive type of hypopharyngeal cancer with poor prognosis, requiring investigation of surgical efficacy and multimodal strategies. This study analyzed surgical resection cases from 2008 to 2022, finding associations between prognosis and factors such as tumor differentiation, lymph node metastasis, and treatment methods. Surgeons should focus on high-risk features and individualized surgical procedures to improve outcomes in postcricoid carcinoma patients.
Article
Radiology, Nuclear Medicine & Medical Imaging
Seo-Youn Choi, Jung Hoon Kim, Sanghyeok Lim, Ji Eun Lee, Hyun Jeong Park, Bora Lee
Summary: By analyzing preoperative CT findings, a prognostic nomogram for gallbladder cancer patients can be established, with different types and invasion statuses influencing prognosis.
EUROPEAN RADIOLOGY
(2021)
Review
Oncology
Andrew Williamson, Christy M. Moen, Mohd Afiq Mohd Slim, Laura Warner, Ben O'Leary, Vinidh Paleri
Summary: Transoral robotic surgery (TORS) as a standalone treatment has low rates of local recurrence (LR) in oropharyngeal cancer. However, there is considerable heterogeneity in margin definitions. Larger multicentre studies are needed to determine the precise margin cut-off required.
Article
Oncology
Naixin Zhang, Catherine Coffman, Ben Wilson, Joann Gold, Scott Baum, Todd Tillmanns, Adam ElNaggar
Summary: Radiofrequency and microwave ablation are safe and effective methods for treating isolated recurrent gynecologic malignancy. Clinical benefit was observed in a majority of patients at 4 months. Adjuvant systemic therapy did not significantly improve progression-free survival.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
(2022)
Article
Oncology
So Jeong Yoon, Seung Soo Hong, Min Jae Gwon, Sang Hyun Shin, Jin Seok Heo, Chang Moo Kang, Kyung Sik Kim, Ho Kyoung Hwang, In Woong Han
Summary: This study aimed to assess the impact of local control (surgical resection or radiofrequency ablation) on survival outcomes in patients with oligo-recurrent distal extrahepatic bile duct (EHBD) cancer. The results showed that patients with local recurrence had better recurrence-free and overall survival compared to those with non-local recurrence. Factors such as lymph node ratio, perineural invasion, timing of recurrence, and platelet-to-lymphocyte ratio at recurrence were found to be independent risk factors for post-recurrence survival in the oligo-recurrent group. Local treatment was associated with improved 3- and 5-year post-recurrence survival in patients with oligo-recurrence, particularly for those with recurrence more than 2 years after initial resection.
Article
Oncology
Stefan Muench, Sylvia Aichmeier, Alexander Hapfelmeier, Marciana-Nona Duma, Markus Oechsner, Marcus Feith, Stephanie E. Combs, Daniel Habermehl
STRAHLENTHERAPIE UND ONKOLOGIE
(2016)
Letter
Oncology
Daniel Habermehl, Stefan Muench
JOURNAL OF SURGICAL ONCOLOGY
(2017)
Article
Oncology
Marciana-Nona Duma, Stefan Muench, Markus Oechsner, Stephanie E. Combs
Article
Oncology
S. Muench, M. Oechsner, S. E. Combs, D. Habermehl
RADIATION ONCOLOGY
(2017)
Article
Oncology
Stefan Muench, Steffi U. Pigorsch, Marcus Feith, Julia Slotta-Huspenina, Wilko Weichert, Helmut Friess, Stephanie E. Combs, Daniel Habermehl
RADIATION ONCOLOGY
(2017)
Article
Oncology
Markus Oechsner, Barbara Chizzali, Michal Devecka, Stefan Muench, Stephanie Elisabeth Combs, Jan Jakob Wilkens, Marciana Nona Duma
STRAHLENTHERAPIE UND ONKOLOGIE
(2017)
Article
Oncology
Antonia Regnier, Jana Ulbrich, Stefan Muench, Markus Oechsner, Dirk Wilhelm, Stephanie E. Combs, Daniel Habermehl
FRONTIERS IN ONCOLOGY
(2017)
Article
Oncology
Hendrik Dapper, Gregor Habl, Christoph Hirche, Stefan Muench, Markus Oechsner, Michael Mayinger, Christina Sauter, Stephanie E. Combs, Daniel Habermehl
Article
Oncology
Marciana Nona Duma, Stefan Muench, Markus Oechsner, Stephanie Elisabeth Combs
Article
Medicine, Research & Experimental
Stefan Muench, Christine Heinrich, Daniel Habermehl, Markus Oechsner, Stephanie E. Combs, Marciana-Nona Duma
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2017)