Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development

Loss of endothelial barrier integrity in mice with conditional ablation of podocalyxin (Podxl) in endothelial cells

(2016) Angélica Horrillo et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Photonic Crystal Optical Tweezers with High Efficiency for Live Biological Samples and Viability Characterization

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A Synthetic Niche for Nephron Progenitor Cells

(2015) Aaron C. Brown et al.   DEVELOPMENTAL CELL

Genome-Wide Analysis of Wilms' Tumor 1-Controlled Gene Expression in Podocytes Reveals Key Regulatory Mechanisms

(2015) M. Kann et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation

(2015) S. Sharmin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

(2015) Minoru Takasato et al.   NATURE

Nephron organoids derived from human pluripotent stem cells model kidney development and injury

(2015) Ryuji Morizane et al.   NATURE BIOTECHNOLOGY

Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids

(2015) Benjamin S. Freedman et al.   Nature Communications

Podocalyxin Regulates Murine Lung Vascular Permeability by Altering Endothelial Cell Adhesion

(2014) Erin J. Debruin et al.   PLoS One

Redefining the In Vivo Origin of Metanephric Nephron Progenitors Enables Generation of Complex Kidney Structures from Pluripotent Stem Cells

(2013) Atsuhiro Taguchi et al.   Cell Stem Cell

Rapid and Efficient Differentiation of Human Pluripotent Stem Cells into Intermediate Mesoderm That Forms Tubules Expressing Kidney Proximal Tubular Markers

(2013) A. Q. Lam et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Exome sequencing and in vitro studies identified podocalyxin as a candidate gene for focal and segmental glomerulosclerosis

(2013) Moumita Barua et al.   KIDNEY INTERNATIONAL

Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells

(2013) Shin-Ichi Mae et al.   Nature Communications

FGF9 and FGF20 Maintain the Stemness of Nephron Progenitors in Mice and Man

(2012) Hila Barak et al.   DEVELOPMENTAL CELL

In Vivo Maturation of Functional Renal Organoids Formed from Embryonic Cell Suspensions

(2012) C. Xinaris et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Chloride Intracellular Channel 4 Is Critical for the Epithelial Morphogenesis of RPE Cells and Retinal Attachment

(2010) Jen-Zen Chuang et al.   MOLECULAR BIOLOGY OF THE CELL

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Dissociation of embryonic kidneys followed by reaggregation allows the formation of renal tissues

(2009) Mathieu Unbekandt et al.   KIDNEY INTERNATIONAL

Neph-Nephrin Proteins Bind the Par3-Par6-Atypical Protein Kinase C (aPKC) Complex to Regulate Podocyte Cell Polarity

(2008) Björn Hartleben et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regeneration of Glomerular Podocytes by Human Renal Progenitors

(2008) E. Ronconi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Tensile forces govern germ-layer organization in zebrafish

(2008) M. Krieg et al.   NATURE CELL BIOLOGY

Selection Against Undifferentiated Human Embryonic Stem Cells by a Cytotoxic Antibody Recognizing Podocalyxin-Like Protein-1

(2008) Andre B. Choo et al.   STEM CELLS