4.2 Article

Generation of human induced pluripotent stem cells from urinary cells of a healthy donor using a non-integration system

Journal

STEM CELL RESEARCH
Volume 21, Issue -, Pages 44-46

Publisher

ELSEVIER
DOI: 10.1016/j.scr.2017.03.019

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Funding

  1. Korea National Institute of Health [2016-NG61002-00, 2016]
  2. Korea Health Promotion Institute [2016-NG61002-00] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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Urinary cells can be an ideal source for generating hiPSCs and progenitors, as they are easily accessible, non-invasive, and universally available. We generated human induced pluripotent stem cells (hiPSCs) from the urinary cells of a healthy donor using a Sendai virus-based gene delivery method. The generated hiPSC line, KSCBi001-A, has a normal karyotype (46,XY). The pluripotency and capacity of multilineage differentiation were characterized by comparison with those of a human embryonic stem cell line. This cell line is registered and available from National Stem Cell Bank, Korea National Institute of Health. (C) 2017 The Authors. Published by Elsevier B.V.

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