Up-regulation of P2X7 receptor-mediated inhibition of GABA uptake by nerve terminals of the human epileptic neocortex

High-affinity GABA uptake by neuronal GAT1 transporters provokes release of [3H]GABA by homoexchange and through GAT1-independent Ca2+-mediated mechanisms

(2015) Cristina Romei et al.   NEUROPHARMACOLOGY

P2X7 receptor activation downmodulates Na+-dependent high-affinity GABA and glutamate transport into rat brain cortex synaptosomes

(2015) A.R. Barros-Barbosa et al.   NEUROSCIENCE

ATP as a multi-target danger signal in the brain

(2015) Ricardo J. Rodrigues et al.   Frontiers in Neuroscience

Increased neocortical expression of the P2X7 receptor after status epilepticus and anticonvulsant effect of P2X7 receptor antagonist A-438079

(2013) Alba Jimenez-Pacheco et al.   EPILEPSIA

Neuronal transporter and astrocytic ATP exocytosis underlie activity-dependent adenosine release in the hippocampus

(2013) Mark J. Wall et al.   JOURNAL OF PHYSIOLOGY-LONDON

Activity and metabolism-related Ca2+ and mitochondrial dynamics in co-cultured human fetal cortical neurons and astrocytes

(2013) W. Fu et al.   NEUROSCIENCE

K+depolarization evokes ATP, adenosine and glutamate release from glia in rat hippocampus: a microelectrode biosensor study

(2012) A Heinrich et al.   BRITISH JOURNAL OF PHARMACOLOGY

Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice

(2011) Tobias Engel et al.   FASEB JOURNAL

The P2X7 receptor–pannexin-1 complex decreases muscarinic acetylcholine receptor–mediated seizure susceptibility in mice

(2011) Ji-Eun Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Calcium-dependent block of P2X7 receptor channel function is allosteric

(2011) Zonghe Yan et al.   JOURNAL OF GENERAL PHYSIOLOGY

Mechanisms of epileptogenesis and potential treatment targets

(2011) Asla Pitkänen et al.   LANCET NEUROLOGY

Enhancement of GABAA-current run-down in the hippocampus occurs at the first spontaneous seizure in a model of temporal lobe epilepsy

(2010) M. Mazzuferi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nicotine-induced and depolarisation-induced glutamate release from hippocampus mossy fibre synaptosomes: two distinct mechanisms

(2009) Victor Bancila et al.   JOURNAL OF NEUROCHEMISTRY

Activation of P2X7receptors decreases glutamate uptake and glutamine synthetase activity in RBA-2 astrocytes via distinct mechanisms

(2008) Jun-Chih Lo et al.   JOURNAL OF NEUROCHEMISTRY

ATP-gated P2X cation-channels

(2008) Michael F. Jarvis et al.   NEUROPHARMACOLOGY