Pharmacokinetics, pharmacodynamics, and safety of USL261, a midazolam formulation optimized for intranasal delivery, in a randomized study with healthy volunteers

Intranasal Drug Delivery: How, Why and What for?

(2016) Anaísa Pires et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Lessons from the RAMPART study-and which is the best route of administration of benzodiazepines in status epilepticus

(2013) Robert Silbergleit et al.   EPILEPSIA

Intranasal Midazolam: Pharmacokinetics and Pharmacodynamics Assessed by Quantitative EEG in Healthy Volunteers

(2012) M Hardmeier et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Intramuscular versus Intravenous Therapy for Prehospital Status Epilepticus

(2012) Robert Silbergleit et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pharmacokinetics and Tolerability of Nasal Versus Intravenous Midazolam in Healthy Dutch Volunteers: A Single-Dose, Randomized-Sequence, Open-Label, 2-Period Crossover Pilot Study

(2011) Nicole M.L. Veldhorst-Janssen et al.   CLINICAL THERAPEUTICS

Intranasal Midazolam vs Rectal Diazepam for the Home Treatment of Acute Seizures in Pediatric Patients With Epilepsy

(2010) Maija Holsti et al.   ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE

Pharmacokinetics and pharmacodynamics of nasally delivered midazolam

(2010) Manuel Haschke et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacokinetics and tolerability of intranasal diazepam and midazolam in healthy adult volunteers

(2009) V. D. Ivaturi et al.   ACTA NEUROLOGICA SCANDINAVICA

A comparison of midazolam nasal spray and diazepam rectal solution for the residential treatment of seizure exacerbations

(2009) Gerrit-Jan de Haan et al.   EPILEPSIA

Intranasal delivery of antiepileptic medications for treatment of seizures

(2009) Daniel P. Wermeling   Neurotherapeutics

Seizure clustering during drug treatment affects seizure outcome and mortality of childhood-onset epilepsy

(2008) M. Sillanpaa et al.   BRAIN

A pharmacokinetic and pharmacodynamic study, in healthy volunteers, of a rapidly absorbed intranasal midazolam formulation

(2008) Daniel P. Wermeling et al.   EPILEPSY RESEARCH