Hydroxymethylcytosine and demethylation of theγ-globingene promoter during erythroid differentiation

Mechanism and Function of Oxidative Reversal of DNA and RNA Methylation

(2014) Li Shen et al.   Annual Review of Biochemistry

New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells

(2014) Mira Jeong et al.   EXPERIMENTAL HEMATOLOGY

TET proteins and 5-methylcytosine oxidation in hematological cancers

(2014) Myunggon Ko et al.   IMMUNOLOGICAL REVIEWS

New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine

(2014) Erika L. Moen et al.   IMMUNOLOGICAL REVIEWS

Fetal Globin Gene Repressors as Drug Targets for Molecular Therapies To Treat the  -Globinopathies

(2014) M. Suzuki et al.   MOLECULAR AND CELLULAR BIOLOGY

Advances in the profiling of DNA modifications: cytosine methylation and beyond

(2014) Nongluk Plongthongkum et al.   NATURE REVIEWS GENETICS

Hydroxymethylation at Gene Regulatory Regions Directs Stem/Early Progenitor Cell Commitment during Erythropoiesis

(2014) Jozef Madzo et al.   Cell Reports

Breathing-in epigenetic change with vitamin C

(2013) Asun Monfort et al.   EMBO REPORTS

CTCF demarcates chicken embryonic α-globingene autonomous silencing and contributes to adult stage-specific gene expression

(2013) Christian Valdes-Quezada et al.   Epigenetics

High Resolution Methylome Analysis Reveals Widespread Functional Hypomethylation during Adult Human Erythropoiesis

(2013) Yiting Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ascorbic Acid Enhances Tet-Mediated 5-Methylcytosine Oxidation and Promotes DNA Demethylation in Mammals

(2013) Ruichuan Yin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

(2013) Kathryn Blaschke et al.   NATURE

Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction

(2013) Lihong Shi et al.   NATURE MEDICINE

Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A

(2013) J. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perturbations of 5-Hydroxymethylcytosine Patterning in Hematologic Malignancies

(2013) Jozef Madzo et al.   SEMINARS IN HEMATOLOGY

Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development

(2012) Yufei Xu et al.   CELL

Effect of AGM and Fetal Liver-Derived Stromal Cell Lines on Globin Expression in Adult Baboon (P. anubis) Bone Marrow-Derived Erythroid Progenitors

(2012) Donald Lavelle et al.   PLoS One

Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors

(2011) E. Pronier et al.   BLOOD

Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation

(2011) Kelly Moran-Crusio et al.   CANCER CELL

Tissue-specific Distribution and Dynamic Changes of 5-Hydroxymethylcytosine in Mammalian Genomes

(2011) Shannon Morey Kinney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Receptors TR2 and TR4 Recruit Multiple Epigenetic Transcriptional Corepressors That Associate Specifically with the Embryonic  -Type Globin Promoters in Differentiated Adult Erythroid Cells

(2011) S. Cui et al.   MOLECULAR AND CELLULAR BIOLOGY

Global DNA Demethylation During Mouse Erythropoiesis in Vivo

(2011) J. R. Shearstone et al.   SCIENCE

Advances in the understanding of haemoglobin switching

(2010) Vijay G. Sankaran et al.   BRITISH JOURNAL OF HAEMATOLOGY

Acquired mutations in TET2 are common in myelodysplastic syndromes

(2009) Saskia M C Langemeijer et al.   NATURE GENETICS