Investigations of primary blast-induced traumatic brain injury

Primary Blast Causes Delayed Effects without Cell Death in Shell-Encased Brain Cell Aggregates

(2018) Thomas W. Sawyer et al.   JOURNAL OF NEUROTRAUMA

The Effect of Underwater Blast on Aggregating Brain Cell Cultures

(2017) Thomas W. Sawyer et al.   JOURNAL OF NEUROTRAUMA

The effect of explosive blast loading on human neuroblastoma cells

(2016) Nicole E. Zander et al.   ANALYTICAL BIOCHEMISTRY

High-Fidelity Simulation of Primary Blast: Direct Effects on the Head

(2016) Thomas W. Sawyer et al.   JOURNAL OF NEUROTRAUMA

Isolated Primary Blast Inhibits Long-Term Potentiation in Organotypic Hippocampal Slice Cultures

(2016) Edward W. Vogel et al.   JOURNAL OF NEUROTRAUMA

Primary Blast Exposure Increases Hippocampal Vulnerability to Subsequent Exposure: Reducing Long-Term Potentiation

(2016) Gwen B. Effgen et al.   JOURNAL OF NEUROTRAUMA

Vascular endothelial growth factor: a neurovascular target in neurological diseases

(2016) Christian Lange et al.   Nature Reviews Neurology

Blast shockwaves propagate Ca2+ activity via purinergic astrocyte networks in human central nervous system cells

(2016) Rea Ravin et al.   Scientific Reports

Dexamethasone Potentiates in Vitro Blood-Brain Barrier Recovery after Primary Blast Injury by Glucocorticoid Receptor-Mediated Upregulation of ZO-1 Tight Junction Protein

(2015) Christopher D Hue et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Vascular endothelial growth factors: multitasking functionality in metabolism, health and disease

(2015) Gina A. Smith et al.   JOURNAL OF INHERITED METABOLIC DISEASE

In vitro studies of primary explosive blast loading on neurons

(2015) Nicole E. Zander et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The Role of Vascular Endothelial Growth Factor in Neurodegeneration and Cognitive Decline

(2015) Timothy J. Hohman et al.   JAMA Neurology

Effects of Blast Overpressure on Neurons and Glial Cells in Rat Organotypic Hippocampal Slice Cultures

(2015) Anna P. Miller et al.   Frontiers in Neurology

Blast Testing Issues and TBI: Experimental Models That Lead to Wrong Conclusions

(2015) Charles E. Needham et al.   Frontiers in Neurology

‘His nerves gave way’: Shell shock, history and the memory of the First World War in Britain

(2014) Fiona Reid   ENDEAVOUR

Computer-Aided Targeting of the PI3K/Akt/mTOR Pathway: Toxicity Reduction and Therapeutic Opportunities

(2014) Tan Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Isolated Primary Blast Alters Neuronal Function with Minimal Cell Death in Organotypic Hippocampal Slice Cultures

(2014) Gwen B. Effgen et al.   JOURNAL OF NEUROTRAUMA

Exposure of the Thorax to a Sublethal Blast Wave Causes a Hydrodynamic Pulse That Leads to Perivenular Inflammation in the Brain

(2014) J. Marc Simard et al.   JOURNAL OF NEUROTRAUMA

Picking the Point of Inhibition: A Comparative Review of PI3K/AKT/mTOR Pathway Inhibitors

(2014) R. Dienstmann et al.   MOLECULAR CANCER THERAPEUTICS

Effects of Low-Level Blast Exposure on the Nervous System: Is There Really a Controversy?

(2014) Gregory A. Elder et al.   Frontiers in Neurology

A Novel Closed-Head Model of Mild Traumatic Brain Injury Caused by Primary Overpressure Blast to the Cranium Produces Sustained Emotional Deficits in Mice

(2014) Scott A. Heldt et al.   Frontiers in Neurology

Neuroprotection Signaling of Nuclear Akt in Neuronal Cells

(2014) Jee-Yin Ahn   Experimental Neurobiology

Gangliosides and Ceramides Change in a Mouse Model of Blast Induced Traumatic Brain Injury

(2013) Amina S. Woods et al.   ACS Chemical Neuroscience

Blood-Brain Barrier Dysfunction after Primary Blast Injury in vitro

(2013) Christopher D. Hue et al.   JOURNAL OF NEUROTRAUMA

Brain Injury: Neuro-Inflammation, Cognitive Deficit, and Magnetic Resonance Imaging in a Model of Blast Induced Traumatic Brain Injury

(2013) Paul Tompkins et al.   JOURNAL OF NEUROTRAUMA

Rat Injury Model under Controlled Field-Relevant Primary Blast Conditions: Acute Response to a Wide Range of Peak Overpressures

(2013) Maciej Skotak et al.   JOURNAL OF NEUROTRAUMA

Repeated Primary Blast Injury Causes Delayed Recovery, but not Additive Disruption, in an In Vitro Blood–Brain Barrier Model

(2013) Christopher D. Hue et al.   JOURNAL OF NEUROTRAUMA

Acute Biomarkers of Traumatic Brain Injury: Relationship between Plasma Levels of Ubiquitin C-Terminal Hydrolase-L1 and Glial Fibrillary Acidic Protein

(2013) Ramon Diaz-Arrastia et al.   JOURNAL OF NEUROTRAUMA

Distinct patterns of expression of traumatic brain injury biomarkers after blast exposure: Role of compromised cell membrane integrity

(2013) Peethambaran Arun et al.   NEUROSCIENCE LETTERS

Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway

(2013) Jiri Polivka et al.   PHARMACOLOGY & THERAPEUTICS

Altered gene expression in cultured microglia in response to simulated blast overpressure: Possible role of pulse duration

(2012) Michael J. Kane et al.   NEUROSCIENCE LETTERS

Shear Forces during Blast, Not Abrupt Changes in Pressure Alone, Generate Calcium Activity in Human Brain Cells

(2012) Rea Ravin et al.   PLoS One

A Multiscale Approach to Blast Neurotrauma Modeling: Part I – Development of Novel Test Devices for in vivo and in vitro Blast Injury Models

(2012) Matthew B. Panzer et al.   Frontiers in Neurology

A Multiscale Approach to Blast Neurotrauma Modeling: Part II: Methodology for Inducing Blast Injury to in vitro Models

(2012) Gwen B. Effgen et al.   Frontiers in Neurology

Neuro-glial and systemic mechanisms of pathological responses in rat models of primary blast overpressure compared to “composite” blast

(2012) Stanislav I. Svetlov   Frontiers in Neurology

Experimental Animal Models for Studies on the Mechanisms of Blast-Induced Neurotrauma

(2012) Mårten Risling et al.   Frontiers in Neurology

Mild Neurotrauma Indicates a Range-Specific Pressure Response to Low Level Shock Wave Exposure

(2011) Pamela J. VandeVord et al.   ANNALS OF BIOMEDICAL ENGINEERING

A mouse model of blast-induced mild traumatic brain injury

(2011) Vardit Rubovitch et al.   EXPERIMENTAL NEUROLOGY

Rodent Model of Direct Cranial Blast Injury

(2011) Reed Kuehn et al.   JOURNAL OF NEUROTRAUMA

Blast Exposure in Rats with Body Shielding Is Characterized Primarily by Diffuse Axonal Injury

(2011) Robert H. Garman et al.   JOURNAL OF NEUROTRAUMA

Effect of Blast Exposure on the Brain Structure and Cognition in Macaca fascicularis

(2011) Jia Lu et al.   JOURNAL OF NEUROTRAUMA

Studies on blast traumatic brain injury using in-vitro model with shock tube

(2011) Peethambaran Arun et al.   NEUROREPORT

Low Level Primary Blast Injury in Rodent Brain

(2011) Pamela B. L. Pun et al.   Frontiers in Neurology

Relationship between orientation to a blast and pressure wave propagation inside the rat brain

(2010) Mikulas Chavko et al.   JOURNAL OF NEUROSCIENCE METHODS

A Multi-Mode Shock Tube for Investigation of Blast-Induced Traumatic Brain Injury

(2010) Dexter V. Reneer et al.   JOURNAL OF NEUROTRAUMA

A Model of Low-Level Primary Blast Brain Trauma Results in Cytoskeletal Proteolysis and Chronic Functional Impairment in the Absence of Lung Barotrauma

(2010) Eugene Park et al.   JOURNAL OF NEUROTRAUMA

The pathobiology of blast injuries and blast-induced neurotrauma as identified using a new experimental model of injury in mice

(2010) Ibolja Cernak et al.   NEUROBIOLOGY OF DISEASE

Mechanisms of blast induced brain injuries, experimental studies in rats

(2010) M. Risling et al.   NEUROIMAGE

Note: A table-top blast driven shock tube

(2010) Michael W. Courtney et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

Morphologic and Biochemical Characterization of Brain Injury in a Model of Controlled Blast Overpressure Exposure

(2010) Stanislav I. Svetlov et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Serum Glial Fibrillary Acidic Protein Is a Highly Specific Biomarker for Traumatic Brain Injury in Humans Compared With S-100B and Neuron-Specific Enolase

(2010) Masahiro Honda et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Neuropathology and Pressure in the Pig Brain Resulting from Low-Impulse Noise Exposure

(2009) Annette Säljö et al.   JOURNAL OF NEUROTRAUMA

Explosive Blast Neurotrauma

(2009) Geoffrey Ling et al.   JOURNAL OF NEUROTRAUMA

Blast-related mild traumatic brain injury: mechanisms of injury and impact on clinical care

(2009) Gregory A. Elder et al.   MOUNT SINAI JOURNAL OF MEDICINE

Case report of a soldier with primary blast brain injury

(2009) Deborah L. Warden et al.   NEUROIMAGE

Injuries From Explosions: Physics, Biophysics, Pathology, and Required Research Focus

(2009) Howard R. Champion et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Up-regulation of reactivity and survival genes in astrocytes after exposure to short duration overpressure

(2008) Pamela J. VandeVord et al.   NEUROSCIENCE LETTERS

Mild Traumatic Brain Injury in U.S. Soldiers Returning from Iraq

(2008) Charles W. Hoge et al.   NEW ENGLAND JOURNAL OF MEDICINE