Article
Environmental Sciences
Sathishkumar Munusamy, Triveni Rajashekhar Mandlimath, Puchakayala Swetha, Abdullah G. Al-Sehemi, Mehboobali Pannipara, Sivasankar Koppala, Paramasivam Shanmugam, Supakorn Boonyuen, Ramyakrishna Pothu, Rajender Boddula
Summary: Doped carbon dots with nitrogen have attracted great attention due to their unique characteristics and have been widely explored in various applications. This article reviews the recent breakthroughs in nitrogen-doped carbon dots for fluorescent sensor applications, including synthetic methods, fluorescent features, sensing mechanisms, and sensor applications for various targets. The potential future directions of nitrogen-doped carbon dots in primary research are also discussed.
ENVIRONMENTAL RESEARCH
(2023)
Review
Anesthesiology
Misty A. Radosevich, Patrick M. Wieruszewski, Erica D. Wittwer
Summary: Tris-hydroxymethyl aminomethane (THAM) is an amino alcohol used clinically to buffer acid loads and raise pH in acidotic conditions. Available since 2020 in the United States, THAM may have clinical utility in managing acid-base derangements in conditions such as liver transplantation and acute respiratory distress syndrome (ARDS). However, clinical evidence supporting its use is limited, and high-quality evaluations are necessary.
ANESTHESIA AND ANALGESIA
(2023)
Article
Chemistry, Multidisciplinary
Wenli Li, Ju Tang, Yuzhao Li, Han Bai, Weizuo Zhang, Jin Zhang, Yiming Xiao, Wen Xu
Summary: This study synthesized multi-color fluorescent materials with nitrogen-doped CNDs using a fast and effective microwave method, and investigated the influence of different raw material ratios on the structure and optical properties of N-CNDs. Results showed that the PL emission wavelength of N-CNDs can be tuned by controlling the N concentration, and the PL intensity is positively correlated with the content of C-O groups on the surface/edges of N-CNDs.
Article
Biochemistry & Molecular Biology
Pingping Liu, Lu Ga, Yong Wang, Jun Ai
Summary: Water-soluble nitrogen-doped carbon dots (N-CDs) with excellent optical and fluorescence thermal properties were prepared by the hydrothermal method using 4-dimethylaminopyridine and N,N'-methylenebisacrylamide as precursors. Co2+ selectively burst the fluorescence of N-CDs, showing high sensitivity and detection limit. In addition, the N-CDs' temperature response and optical properties make them potential candidates in the field of fluorescent inks and temperature sensing.
Article
Biochemical Research Methods
Ulrich Kratzer, Cornelia Sommersdorf, Sandra Maier, Teresa R. Wagner, Markus Templin, Thomas O. Joos, Ulrich Rothbauer, Anne Zeck, Oliver Poetz
Summary: N-Hydroxysuccinimide esters are commonly used to modify biomolecules like antibodies or proteins. Primary amine groups react with the ester to form covalent amide bonds, and TRIS does not interfere with biotinylation using NHS chemistry.
BIOCONJUGATE CHEMISTRY
(2021)
Article
Engineering, Chemical
Xiaochen Zhao, Xudong Wang, Yonghao Dong, Hongmin Zhang, Wei Zhao, Jin Wang, Lei Wang
Summary: By intercalating and introducing adhesive molecules, the interlayer spacing of graphitic carbon nitride nanosheets is expanded, resulting in larger interlayer channels and improved separation performance and water flux of the composite membrane.
JOURNAL OF MEMBRANE SCIENCE
(2022)
Article
Biochemical Research Methods
Lubna Ghani, Xiang Zhang, Chastine F. Munk, Parameswaran Hariharan, Baoliang Lan, Hong Sik Yun, Bernadette Byrne, Lan Guan, Claus J. Loland, Xiangyu Liu, Pil Seok Chae
Summary: High-resolution membrane protein structures are crucial for understanding cellular processes and drug discovery. Traditional detergents have limited stability, necessitating the development of novel agents for membrane protein structural study. The designed TTGs showed improved stability of membrane proteins compared to maltoside detergents, likely due to their high hydrophobicity, optimal hydrophilic-lipophilic balance, and absence of cis-trans isomerism.
BIOCONJUGATE CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Y. A. Kondratenko, A. A. Nikonorova, A. A. Zolotarev, M. Y. Arsent'ev, G. G. Nyanikova, V. L. Ugolkov, E. I. Sysoev, T. A. Kochina
Summary: In this study, new coordination compounds analogues of hydrometallatranes were synthesized and characterized using FT-IR spectroscopy, mass spectrometry, and elemental analysis. The crystal structure of the TRIS complex with Cu(II) cinnamate was determined by X-ray diffraction, and the structural parameters and gap energy were calculated using the DFT method. The effect of some TRIS hydrometallatranes on the growth of corrosion aggressive thionic bacteria was also studied.
INORGANICA CHIMICA ACTA
(2022)
Article
Engineering, Chemical
Ding Ling Gao, Yan Xue Xue, Fei Fei Dai, Yu Xiang Liu, Na Qin, Ya Yuan Zhang, Jian Hua Chen, Qian Yang
Summary: In this study, a polyaniline-p-phenylenediamine composite membrane with a nanoparticle-like surface morphology was fabricated, and its surface was hydroxylated by interfacial polymerization of Tris(hydroxymethyl)aminomethane (THAM). The introduction of THAM enhanced the membrane's hydrophilicity, electro-negativity, and antifouling performance. The TPAPD/PES composite membrane showed improved flux and phosphate rejection, indicating its potential for practical applications in wastewater treatment.
SEPARATION AND PURIFICATION TECHNOLOGY
(2024)
Article
Chemistry, Physical
Mingyu Shin, Chanho Noh, Yongjin Chung, Do-Heyoung Kim, Yongchai Kwon
Summary: Tris-functionalized carbon nanotube Tris-CNT is proposed as a catalyst to enhance the redox reactivity of vanadium ions in VRFB. The surface of Tris-CNT, rich in oxygen functional groups, plays a key role in facilitating the redox reaction. Evaluation shows that Tris-CNT significantly improves VRFB performance with increased reactivity, capacity, and energy efficiency compared to CA-CNT.
APPLIED SURFACE SCIENCE
(2021)
Article
Chemistry, Inorganic & Nuclear
Mohammad taghi Bagherian Jamnani, Rahimeh Hajinasiri, Hossein Ghafuri, Zinatossadat Hossaini
Summary: Here, we present an impressive heterogeneous catalytic system g-C3N4/THAM. The novel g-C3N4/THAM nanocatalysts were characterized by various analyzing methods and demonstrated excellent efficiency in multicomponent reactions. The environmentally friendly g-C3N4/THAM nanocatalyst catalyzed the reactions in the presence of ethanol as a green solvent.
Article
Chemistry, Analytical
Hari Krishna Sadhanala, Saurav Aryal, Kusha Sharma, Ziv Orpaz, Shulamit Michaeli, Aharon Gedanken
Summary: In this study, photoluminescent N-doped carbon dots were synthesized and used for the selective detection and imaging of intracellular magnesium ions. This is the first report of using carbon dots for sensing and imaging of magnesium ions in cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Green & Sustainable Science & Technology
Meng Chen, Hu Yang, Zhen-liang Xu, Chong Cheng
Summary: This study demonstrated the separation of anionic dyes in saline solutions using uncharged PAN-Tris UF membranes. The membrane pore size and zeta potential significantly influenced the rejection behavior of dyes, with membrane performance depending on the molecular size, valence, and membrane properties. Furthermore, investigation of the separation mechanism revealed insights that could guide the rational design of UF membranes for highly effective treatments of dye-containing wastewater.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Chemistry, Physical
Anees Qurtulen, Anees Ahmad, Hesam Salimi Shahraki, Nimra Shakeel, Rani Bushra
Summary: The study demonstrates the potential of nitrogen-doped carbon quantum dots (N-CQDs) prepared from natural waste resources in wastewater treatments and biomedical applications. The N-CQDs show stable fluorescent properties, good biocompatibility, and high photocatalytic activity for various dyes. The nanomaterial holds great promise in biosensing applications and efficient wastewater treatment.
SURFACES AND INTERFACES
(2023)
Article
Biochemistry & Molecular Biology
Kuei-Hsiang Chen, You-Ren Lai, Nguyen The Duc Hanh, Steven S. -S. Wang, Yu-Kaung Chang
Summary: In this study, a polyacrylonitrile nanofiber membrane functionalized with tris(hydroxymethyl)aminomethane was used as an affinity membrane for lysozyme adsorption in membrane chromatography. The dynamic adsorption behavior of lysozyme was investigated under various operating parameters, and the results showed that the pseudo-second-order kinetic model fitted well with the experimental data. The breakthrough curve characteristics were analyzed using different dynamic adsorption models, and the Yoon-Nelson model was found to be the best fit for the experimental data.
Article
Polymer Science
Suman Kumar Ghosh, Tushar Kanti Das, Sayan Ganguly, Krishnendu Nath, Sangit Paul, Debabrata Ganguly, Narayan Chandra Das
Summary: Clay-reinforced polymer composites have been improved by using the 'grafting to' silylation method to enhance their compatibility with thermoplastic polymers. The resulting nanocomposites showed improved performance properties, such as higher tensile strength and Young modulus, better filler dispersion, as well as reduced oxygen and water vapor transmission rates. These nanocomposites could be ideal alternatives for flexible thermoplastic composites as packaging materials.
Article
Environmental Sciences
Trisita Ghosh, Suvendu Nandi, Swarup Krishna Bhattacharyya, Suman Kumar Ghosh, Mahitosh Mandal, Pallab Banerji, Narayan Ch Das
Summary: This study developed photoluminescent heteroatom-doped carbon dots for cancer cell imaging through a simple hydrothermal procedure. The carbon dots exhibited spherical shape with an average diameter of 3.5 nm. They showed low cytotoxicity and good compatibility with normal glial cells, and were able to emit green fluorescence inside cells with imaging-trackable ability.
ENVIRONMENTAL RESEARCH
(2023)
Article
Nanoscience & Nanotechnology
Poushali Das, Masoomeh Sherazee, Parham Khoshbakht Marvi, Syed Rahin Ahmed, Aharon Gedanken, Seshasai Srinivasan, Amin Reza Rajabzadeh
Summary: In this study, a pollution-free technique was developed to fabricate a heteroatom-doped carbon dot immobilized fluorescent biopolymer composite for functional textiles. The composite exhibited excellent antioxidant and antimicrobial properties, making it suitable for medical and healthcare applications. Hospital-acquired infections pose a significant financial burden on healthcare systems worldwide.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Environmental Sciences
Sangit Paul, Manjur Rahaman, Suman Kumar Ghosh, Ankur Katheria, Tushar Kanti Das, Shailendra Patel, Narayan Ch Das
Summary: Thermal pyrolysis of waste tires is an effective method for material and energy recovery. The pyrolytic carbon black (CBp) obtained from this process has similar characteristics to commercially available carbon black and can be used in rubber product manufacturing. The average yields of CBp and pyrolytic liquid were 48.2 wt% and 46.3 wt% respectively. CBp was found to have higher oxygen and sulfur content compared to commercially available carbon black.
JOURNAL OF MATERIAL CYCLES AND WASTE MANAGEMENT
(2023)
Article
Engineering, Electrical & Electronic
Krishnendu Nath, Suman Kumar Ghosh, Palash Das, Ankur Katheria, Narayan Ch. Das
Summary: In this study, a facile method for preparing conductive binary biodegradable polymer nanocomposite films is reported. These films are based on ester-based thermoplastic polyurethane (TPU) and poly (butylene adipate-co-terephthalate) (PBAT), and the acid-functionalized multiwalled carbon nanotube (MO) is preferentially incorporated into the PBAT phase of the binary polymer matrix through solvent mixing technique.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2023)
Article
Materials Science, Composites
Suman Kumar Ghosh, Krishnendu Nath, Soumya Sarathi Ganguly, Tushar Kanti Das, Sangit Paul, Trisita Ghosh, Amit Kumar Das, Narayan Ch. Das
Summary: This study investigates the application of polymer/graphene-based nanocomposite films in packaging, electronics, and pharmaceutical industries. The addition of graphene derivatives enhances the physico-mechanical properties, thermal conductivity, and barrier properties of the films, with antibacterial and electromagnetic interference shielding effects. These thermoplastic nanocomposite films with high thermal conductivity are an excellent choice for bacteria-resistant packaging and efficient thermal management EMI shields in electronics.
POLYMER COMPOSITES
(2023)
Article
Nanoscience & Nanotechnology
Syed Rahin Ahmed, Ana Gomez Cardoso, Herlys Viltres Cobas, Poushali Das, Aicheng Chen, Seshasai Srinivasan, Amin Reza Rajabzadeh
Summary: This study presents a hydrothermal synthesis method for fluorescent graphdiyne quantum dots (GDY QDs) from graphdiyne sheets and reports, for the first time, the nanozymatic activity of GDY QDs. The GDY QDs catalyze the oxidation of H2O2 through peroxidase biomimetic nature and enable detection of H2O2 and dopamine. The findings of this study have important implications for the development of carbon-based nanocrystals with enzyme-mimicking nature for analytical approaches, particularly colorimetric nanobiosensors.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Ankur Katheria, Palash Das, Jasomati Nayak, Krishnendu Nath, Suman Kumar Ghosh, Sangit Paul, Narayan Ch Das
Summary: In this study, electrically conductive polymer composites were developed by preferentially localizing MWCNTs in a co-continuous EMA/TPO binary blend system. The addition of 3 to 5 wt% of MWCNT achieved the electrical percolation threshold. FESEM and TEM images showed a co-continuous morphology with MWCNTs located in the EMA phase of the blend. The DC and AC conductivity of the composite significantly increased with the addition of MWCNTs. A total EMI shielding effectiveness of -35 dB was achieved by adding 15 wt% MWCNTs into the matrix in the frequency range of 14.5-20.0 GHz, along with good thermal conductivity, dielectric properties, and mechanical properties.
JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS
(2023)
Article
Nanoscience & Nanotechnology
Syed Rahin Ahmed, Masoomeh Sherazee, Poushali Das, Jesse Dondapati, Seshasai Srinivasan, Amin Reza Rajabzadeh
Summary: Quantum dots with unconventional properties, such as borophene quantum dots (BQDs), have been synthesized and found to exhibit nanozymatic activity and antibacterial activity, in addition to their conventional fluorescence emission nature. Through an electrochemical process, the nanozymatic activity of BQDs was significantly enhanced, enabling the detection of H2O2 with exceptional sensitivity. The remarkable findings of this study have the potential to open a pathway for the future development of electroassisted nanozymatic detection methods.
ACS APPLIED NANO MATERIALS
(2023)
Article
Polymer Science
Ankur Katheria, Palash Das, Suman Kumar Ghosh, Jasomati Nayak, Krishnendu Nath, Sangit Paul, Shovan Biswas, Narayan Ch. Das
Summary: Polymer nanocomposites have gained significant interest for electromagnetic interference (EMI) shielding applications due to their lightweight, anticorrosive, and tunable properties. This study developed a composite material with reduced graphene oxide (RGO) as a conductive filler, achieving a low electrical percolation threshold and outstanding shielding effectiveness. The composite also exhibited promising thermal conductivity and mechanical properties, offering potential for thermal management and microwave shielding in EMI-sensitive applications.
JOURNAL OF POLYMER RESEARCH
(2023)
Article
Nanoscience & Nanotechnology
Poushali Das, Sayan Ganguly, Andreas Rosenkranz, Bo Wang, Jinhong Yu, Seshasai Srinivasan, Amin Reza Rajabzadeh
Summary: MXenes are highly versatile materials that can compete with and outperform graphene in certain applications. The self-restacking issue can be addressed by hybridizing with low-dimensional nanostructures. This review highlights recent advancements and emerging applications in this field, as well as the challenges that need to be overcome.
MATERIALS TODAY NANO
(2023)
Article
Polymer Science
Krishnendu Nath, Suman Kumar Ghosh, Palash Das, Ankur Katheria, Narayan Chandra Das
Summary: This study presents a practical method for producing biodegradable electromagnetic interference (EMI) shield films made of thermoplastic polyurethane (TPU), polybutylene adipate-co-terephthalate (PBAT), and modified multi-walled carbon nanotubes (MWCNT). The distribution of nanoparticles in the polymer matrix was found to play a key role in determining the EMI shielding efficiency.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Chemistry, Physical
Masoomeh Sherazee, Syed Rahin Ahmed, Poushali Das, Seshasai Srinivasan, Amin Reza Rajabzadeh
Summary: This paper reports a novel approach for the synthesis of carbon quantum dot-gold nanoparticles and demonstrates the enhancement of their catalytic activity through electrochemical means. The method enables rapid and sensitive detection in field applications and can be utilized to improve and exploit enzymatically dependent reactions.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)