Recent progress in the development of fluorescent probes for the detection of hypochlorous acid

As one of the reactive oxygen species, hypochlorous acid (HOCl) may be associated with various diseases. To understand the roles of HOCl in living organism, fluorescent probes for imaging HOCl in living systems have been developed fast in recent years owing to their high selectivity, excellent sensitivity and spectral resolution. In this review, we summarized and highlighted the recent advances in the development and application of HOCl fluorescent probes. This review is focused on the detection mechanisms of probes for HOCl. According to the various recognition groups, we divided the HOCl fluorescence probes into five parts and discussed detection mechanisms, respectively. (C) 2016 Elsevier B.V. All rights reserved.