Article
Computer Science, Information Systems
Christopher Conrad, Saba Al-Rubaye, Antonios Tsourdos
Summary: Intelligent vehicular cyber-physical systems (ICPSs) improve the reliability, efficiency, and adaptability of urban mobility systems, particularly enabling autonomous transportation in smart cities. However, their deployment raises concerns about safety assurance, cybersecurity threats, communication reliability, and data management. This paper presents a comprehensive CPS as a solution to address these challenges and advance the development of ICPSs and intelligent vehicular algorithms.
Article
Automation & Control Systems
Kemi Ding, Xiaoqiang Ren, Hongsheng Qi, Guodong Shi, Xiaofan Wang, Ling Shi
Summary: This paper investigates the channel sharing and power allocation among sensors in a cyber-physical system, proposing a solution in a non-cooperative game framework. The main contents include optimal power allocation for channel sharing between primary and potential sensors, platform-set price strategies, and algorithm design.
Article
Computer Science, Hardware & Architecture
Rose Bohrer, Bashima Islam
Summary: This article introduces a new general-purpose formal verification approach for cyber-physical properties of intermittent systems. By defining a high-level modeling and specification language and proving its reduction to hybrid games, our approach enables rigorous proofs for these systems.
IEEE TRANSACTIONS ON COMPUTER-AIDED DESIGN OF INTEGRATED CIRCUITS AND SYSTEMS
(2022)
Article
Automation & Control Systems
Xirong Ning, Jin Jiang
Summary: This article presents a modular experimental platform to support cyber security assessment and enhancement of cyber-physical systems. The platform is designed with a hardware-based prototype and provides effective methods to identify vulnerabilities and evaluate different security enhancement strategies.
IEEE TRANSACTIONS ON INDUSTRIAL INFORMATICS
(2022)
Article
Automation & Control Systems
Dina Mikhaylenko, Ping Zhang
Summary: This article introduces a new attack strategy called local covert attack, which can be made completely stealthy by applying decoupling technique or by combining basic idea of covert attack and zero-dynamics attack.
IEEE TRANSACTIONS ON AUTOMATIC CONTROL
(2022)
Article
Engineering, Multidisciplinary
Zhengcheng Dong, Meng Tian
Summary: This paper proposes a model of heterogeneous cyber-physical systems with weak dependency, studying system vulnerability under scenarios of physical edge-removal and edge-overload. The results suggest that attacking high-load edges is more effective in edge-removal scenarios, while adding extra load to low-load edges performs better in edge-overload scenarios.
IEEE TRANSACTIONS ON NETWORK SCIENCE AND ENGINEERING
(2021)
Article
Automation & Control Systems
Charalambos Konstantinou, Olugbenga Moses Anubi
Summary: This article investigates the problem of optimal estimation with sensing measurements subject to arbitrary corruption in cyber-physical energy systems. By using prior information and an optimization approach, it enhances the resilience of the systems.
IEEE TRANSACTIONS ON INDUSTRIAL INFORMATICS
(2022)
Article
Engineering, Industrial
Zhengcheng Dong, Meng Tian, Xin Li, Jingang Lai, Ruoli Tang
Summary: This paper proposes a spatial CPPS model and an information link addition strategy to improve the invulnerability of cyber-physical power systems against cascading failures. Statistical results show that adding additional information links can enhance the reliability of CPPS. The AL-BL mode performs the best under severe attacks, while the AL-CL mode performs the worst.
RELIABILITY ENGINEERING & SYSTEM SAFETY
(2022)
Article
Automation & Control Systems
Kian Gheitasi, Walter Lucia
Summary: The article proposes a networked control architecture to ensure plant safety in the presence of cyber-attacks. By introducing an emergency controller, attack detectors, and the concept of a robust N-step attack-safe region, the trajectory of the plant is proven to be uniformly ultimately bounded regardless of attacker actions.
INTERNATIONAL JOURNAL OF ROBUST AND NONLINEAR CONTROL
(2021)
Article
Computer Science, Information Systems
Publio M. Lima, Lilian K. Carvalho, Marcos V. Moreira
Summary: This paper addresses the security challenges of cyber-physical systems (CPS) in smart industries, focusing on protection against cyber attacks. The CPS is abstracted as a Discrete-Event System (DES), and the paper considers cyber attacks involving eavesdropping on communication channels to detect secret system behavior. To prevent the attacker from accessing secret information, a new cryptographic scheme called event-based cryptography is introduced. The paper defines the confidentiality property of DES, presents necessary and sufficient conditions for confidentiality, proposes a test to verify the property, and provides a method to create an encryption function for CPS to ensure confidentiality given a bounded secret language length.
INFORMATION SCIENCES
(2023)
Article
Automation & Control Systems
Woo-Hyun Ko, Jorge A. Ramos-Ruiz, Tong Huang, Jaewon Kim, Hasan Ibrahim, Prasad N. Enjeti, P. R. Kumar, Le Xie
Summary: This article proposes a dynamic watermarking technique to defend against cyberattacks on grid-connected inverter systems. By superimposing a secret signal onto the actuator signal and detecting this watermark in the measurement data returned from the sensors, malicious attacks can be effectively detected.
IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS
(2023)
Review
Engineering, Electrical & Electronic
Jyotirmoy Bhardwaj, Joshin P. Krishnan, Diego F. Larios Marin, Baltasar Beferull-Lozano, Linga Reddy Cenkeramaddi, Christopher Harman
Summary: With the increasing demand to equip Smart Water Networks (SWN) with advanced sensing and computation capabilities, Cyber-Physical Systems (CPSs) have emerged as an important research area for intelligently sensing the state of SWN and reacting autonomously in crisis scenarios. CPSs can integrate physical components of SWN and provide technological frameworks for data analytics, decision making, and control. Collaboration of diverse scientific disciplines is crucial for efficient deployment of CPS in SWN, requiring a common methodology in terms of design approaches.
IEEE SENSORS JOURNAL
(2021)
Article
Automation & Control Systems
Wei Xing, Xudong Zhao, Tamer Basar, Weiguo Xia
Summary: This article discusses remote state estimation in cyber-physical systems with multiple sensors. A dynamic nonzero-sum game with asymmetric information is proposed to model the interactions among sensors. By transforming the game with asymmetric information into a game with symmetric information, a subclass of Nash equilibria called common information-based Markov perfect equilibria can be obtained. The backward induction algorithm is used to find the equilibria. A numerical example is provided to illustrate the results obtained.
IEEE TRANSACTIONS ON AUTOMATIC CONTROL
(2022)
Article
Engineering, Marine
Iosif Progoulakis, Paul Rohmeyer, Nikitas Nikitakos
Summary: The integration of IT, OT, and human factors in maritime assets is critical for efficient and safe operation, involving various IT and OT components and functions with diverse communication paths and evolving cyber security threats.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2021)
Article
Computer Science, Artificial Intelligence
Prachi Pratyusha Sahoo, Aris Kanellopoulos, Kyriakos G. Vamvoudakis
Summary: This article presents a novel intermittent learning scheme based on Skinner's operant conditioning techniques, which approximates the optimal policy while decreasing information transfer. Traditional reinforcement learning schemes can lead to overutilization of limited resources and face the risk of malicious interference. Simulation results demonstrate the efficacy of the proposed approach.
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS
(2023)
Article
Chemistry, Physical
Owais Al-Aqtasha, Ferenc Farkas, Andras Sapi, Imre Szenti, Tamas Boldizsar, Kornelia B. Abrahamne, Akos Kukovecz, Zoltan Konya
Summary: This paper discusses the overlooked source of emissions from non-road mobile machinery and proposes a solution using an efficient catalyst. By analyzing the relevant properties of the catalyst and its performance, a significant reduction in CO and NOx emissions is achieved. This research will be the first part of a tailored solution to reduce emissions from non-road mobile machinery.
REACTION KINETICS MECHANISMS AND CATALYSIS
(2023)
Article
Nanoscience & Nanotechnology
Seyed Hossein Hosseini-Shokouh, Jin Zhou, Ethan Berger, Zhong-Peng Lv, Xiaodan Hong, Vesa Virtanen, Krisztian Kordas, Hannu -Pekka Komsa
Summary: Cost-effective and high-performance H2S sensors are in demand for human health and environmental monitoring. MXenes, specifically 2D transition-metal carbides and nitrides, have shown potential for gas sensing due to their good conductivity and abundant surface functional groups. This study reports a negative response of pristine Ti3C2Tx thin films for H2S sensing and further improvement of sensor performance using a composite of Ti3C2Tx flakes and conjugated polymers (PDS-Cl), achieving a thirtyfold sensing enhancement and a low limit of detection. The findings also contribute to a better understanding of the sensing mechanism and selectivity of MXene-based composites.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Physical
Aleksandar Markovic, Sladana Savic, Andrej Kukuruzar, Zoltan Konya, Dragan Manojlovic, Milos Ognjanovic, Dalibor M. Stankovic
Summary: In this study, different synthesis procedures for making PbO2-graphitic carbon nitride (g-C3N4) electrode were examined for the electrochemical degradation of Reactive Black 5 (RB5) textile azo dye. PbO2 with varying morphology was formed through the reaction of PbOH3- with ClO- in the presence of different surfactants (CTAB and TBAP) under conventional conditions. The obtained materials were combined with g-C3N4 and characterized morphologically and electrochemically. The composite of PbO2 synthesized using CTAB as template and g-C3N4 showed the best performance for RB5 dye removal, suggesting its potential for wastewater treatment and pollutant removal.
Article
Chemistry, Physical
Gabor Vari, Csaba Vass, Gyula Halasi, Laszlo Szabo, Krisztian Palotas, Peter Dombi, Andras Berko, Laszlo Ovari, Zoltan Konya
Summary: In this study, the thermal properties of Au and Rh deposits on hexagonal boron nitride (h-BN) nanomesh prepared on Rh(1 1 1) were compared using various techniques. Both metals showed Volmer-Weber growth at room temperature, and agglomeration, intercalation, and desorption were observed upon annealing. For Rh, an additional encapsulation mechanism was suggested. The agglomeration of gold nanoparticles was found to be faster than that of rhodium, and gold atoms diffused below h-BN at higher temperatures. Intercalation of individual adatoms was observed during deposition, and it required higher temperatures for rhodium due to its slower diffusion and higher probability of nucleation.
APPLIED SURFACE SCIENCE
(2023)
Article
Multidisciplinary Sciences
Hadid Sukmana, Gergo Ballai, Tamas Gyulavari, Erzsebet Illes, Gabor Kozma, Zoltan Konya, Cecilia Hodur
Summary: The study investigated the removal of methylene blue (MB) and basic red 9 (BR9) dyes using Hungarian rice husk (HRH) and Indonesian rice husk (IRH) as bioadsorbents. Various factors influencing the biosorption were evaluated using different techniques. The results showed that both HRH and IRH were effective in removing MB and BR9 through binary biosorption.
Article
Environmental Sciences
Zsuzsanna Kolbert, Arpad Molnar, Kamilla Kovacs, Sara Liptak-Lukacsik, Peter Benko, Reka Szollosi, Katalin Gemes, Laszlo Erdei, Andrea Ronavari, Zoltan Konya
Summary: This study compared the effects of different doses of multi-walled carbon nanotubes (MWCNTs) on Brassica napus and Solanum lycopersicum seedlings. It was found that higher concentrations of MWCNTs negatively affected root viability and cell proliferation, leading to oxidative stress and increased toxicity. The toxicity was more severe in Solanum lycopersicum compared to Brassica napus.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Green & Sustainable Science & Technology
Loghman Rezaei, Samrand Saeidi, Andras Sapi, M. R. Abdollahi Senoukesh, Gyula Grof, Wei-Hsin Chen, Zoltan Konya, Jiri Jaromir Klemes
Summary: The solar chimney power plant is a simple and clean technology to generate electricity from solar radiation. This study developed a novel collector design with hanging metallic tubes to improve efficiency. Experimental and computational fluid dynamics analysis validated the new design and found that the metallic tubes significantly affected temperature and velocity distribution. The efficiency of the collector increased with the hanging metallic tubes and was also influenced by the geometry variation.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Nanoscience & Nanotechnology
Gergo Ballai, Tomaz Kotnik, Matjaz Finsgar, Albin Pintar, Zoltan Konya, Andras Sapi, Sebastijan Kovacic
Summary: Highly porous metal oxide-polymer nanocomposites with unique structural and functional features were prepared by coating metal oxide nanolayers onto polyHIPE beads using the ALD technique. It was found that the number of ALD cycles affected the thickness and crystallinity of the nanolayers. Furthermore, the ALD-derived TiO2-polyHIPE beads exhibited superior activity in photocatalytic oxidation.
ACS APPLIED NANO MATERIALS
(2023)
Article
Green & Sustainable Science & Technology
Hadid Sukmana, Etelka Tombacz, Gergo Ballai, Gabor Kozma, Zoltan Konya, Cecilia Hodur
Summary: This study compares Indonesian and Hungarian rice husks as bio-adsorbents for removing dyes from aqueous solutions and finds that they are potential adsorbents.
Article
Chemistry, Physical
Jin Zhou, Seyed Hossein Hosseini Shokouh, Linfan Cui, Topias Jarvinen, Olli Pitkanen, Zhong-Peng Lv, Krisztian Kordas
Summary: A core-shell composite, Ti3C2Tx@croconaine (poly(1,5-diaminonaphthalene-croconaine), PDAC), for NH3 detection, was prepared by a facile in situ polymerization reaction, which exhibits significantly enhanced sensitivity and detection limit compared to pristine Ti3C2Tx. The improved sensing performance is attributed to the presence of PDAC facilitating the adsorption of NH3 and changing the tunneling conductivity between Ti3C2Tx domains.
NANOSCALE HORIZONS
(2023)
Article
Materials Science, Multidisciplinary
Petra S. Palvolgyi, Mikko Kokkonen, Rafal Sliz, Heli Jantunen, Krisztian Kordas, Sami Myllymaki
Summary: This study demonstrates a lightweight dielectric bullet-shaped lens operating in the frequency range of 110-170 GHz, which is used to guide the propagation of electromagnetic waves. The material of the lens is a composite of silica nanoshells and poly(methylmethacrylate), which is highly porous and has low dielectric permittivity and loss tangent. The size of the collimated beam and the increase of the corresponding field strength vary depending on the frequency of the waves.
ADVANCED PHOTONICS RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Krisztina Karadi, Thanh-Truc Nguyen, Adel Anna Adam, Kornelia Baan, Andras Sapi, Akos Kukovecz, Zoltan Konya, Pal Sipos, Istvan Palinko, Gabor Varga
Summary: Glucose-to-fructose isomerization is a key process in biomass conversion to fine chemicals. Catalyzing glucose isomerization in ethanol using hydrotalcite has shown promising results. The study reveals the relationship between the structural and textural parameters of hydrotalcites and their catalytic performance, indicating that hydrophilicity and LDH surface factors are the determining factors. A comparable catalytic performance with lower reaction temperature can be achieved using easily recyclable LDH with suitable surface features.
Article
Chemistry, Physical
Marianna Kocsis, Kornelia Baan, Sandor B. Otvos, Akos Kukovecz, Zoltan Konya, Pal Sipos, Istvan Palinko, Gabor Varga
Summary: Oxidative dehydrogenative coupling (ODC) is a versatile and sustainable tool for forming new C-C, C-O, and N=N bonds. However, it is less explored for N-heterocycle synthesis. In this study, we developed an environmentally friendly synthesis strategy to selectively produce azobenzenes, quinolines, and quinoxalines through the ODC of anilines and 2-aminoanilies with vicinal diols. The reactions were catalyzed by bifunctional catalysts based on transition metal oxides/Bi(iii), enabling solvent-, additive-, oxidant-, and base-free cyclizations/couplings. The catalysts showed high robustness and reusability.
CATALYSIS SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Physical
Peter B. Nagy, Lakshmi Shiva Shankar, Marton Szabados, Hala Roumia, Akos Kukovecz, Robert Kun, Tamas Szabo
Summary: In this study, the interactions between SNPs, polycations, and GO were quantitatively characterized, and it was found that mass ratios of polycation to SNP beyond the isoelectric point could promote the heteroaggregation between SNPs and GO and alleviate the migration of lithium polysulfides. The synthesized composite cathode exhibited excellent electrochemical performance.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2024)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
