Journal
SENSORS
Volume 17, Issue 6, Pages -Publisher
MDPI
DOI: 10.3390/s17061293
Keywords
cell-based biosensor; cell microarray; microfabrication; toxicology; drug discovery; biosensing; positional array; suspension array
Funding
- National Research Foundation (NRF) - Ministry of Science, ICT and Future Planning (MSIP) [2015R1D1A1A01060444, NRF-2015R1D1A1A01060710, 2009-0093823]
- Korean Health Technology R&D Project through the Korean Health Industry Development Institute (KHIDI) [HI15C1744, HI15C2807]
- Korea Health Promotion Institute [HI15C1744020017, HI15C2807030016] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
- National Research Foundation of Korea [2015R1D1A1A01060710, 2009-0093823, 2015R1D1A1A01060444] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Ask authors/readers for more resources
Due to the recent demand for high-throughput cellular assays, a lot of efforts have beenmade on miniaturization of cell-based biosensors by preparing cell microarrays. Various microfabrication technologies have been used to generate cell microarrays, where cells of different phenotypes are immobilized either on a flat substrate (positional array) or on particles (solution or suspension array) to achieve multiplexed and high-throughput cell-based biosensing. After introducing the fabrication methods for preparation of the positional and suspension cell microarrays, this review discusses the applications of the cell microarray including toxicology, drug discovery and detection of toxic agents.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available