Tissue compartmentalization of T cell responses during early life

Dendritic Cells Display Subset and Tissue-Specific Maturation Dynamics over Human Life

(2017) Tomer Granot et al.   IMMUNITY

Protecting the Newborn and Young Infant from Infectious Diseases: Lessons from Immune Ontogeny

(2017) Tobias R. Kollmann et al.   IMMUNITY

Reduced generation of lung tissue–resident memory T cells during infancy

(2017) Kyra D. Zens et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Airway CD8+T Cells Are Associated with Lung Injury during Infant Viral Respiratory Tract Infection

(2016) Thomas J. Connors et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Lin28b Regulates Fetal Regulatory T Cell Differentiation through Modulation of TGF-β Signaling

(2016) Yelena Bronevetsky et al.   JOURNAL OF IMMUNOLOGY

Viral Bronchiolitis in Children

(2016) H. Cody Meissner   NEW ENGLAND JOURNAL OF MEDICINE

Mucosal BCG Vaccination Induces Protective Lung-Resident Memory T Cell Populations against Tuberculosis

(2016) Carolina Perdomo et al.   mBio

Skin-resident memory CD4+T cells enhance protection againstLeishmania majorinfection

(2015) Nelson D. Glennie et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MF59 Mediates Its B Cell Adjuvanticity by Promoting T Follicular Helper Cells and Thus Germinal Center Responses in Adult and Early Life

(2015) Beatris Mastelic Gavillet et al.   JOURNAL OF IMMUNOLOGY

Early-life compartmentalization of human T cell differentiation and regulatory function in mucosal and lymphoid tissues

(2015) Joseph J C Thome et al.   NATURE MEDICINE

Community-Acquired Pneumonia among U.S. Children

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection

(2015) Agnieszka Jozwik et al.   Nature Communications

Active suppression of intestinal CD4+TCRαβ+ T-lymphocyte maturation during the postnatal period

(2015) Natalia Torow et al.   Nature Communications

Lower respiratory tract infection caused by respiratory syncytial virus: current management and new therapeutics

(2015) Natalie I Mazur et al.   Lancet Respiratory Medicine

Spatial Map of Human T Cell Compartmentalization and Maintenance over Decades of Life

(2014) Joseph J.C. Thome et al.   CELL

Common Dermatologic Manifestations of Primary Immune Deficiencies

(2014) Manisha Relan et al.   CURRENT ALLERGY AND ASTHMA REPORTS

CD4+ T Cell Help Guides Formation of CD103+ Lung-Resident Memory CD8+ T Cells during Influenza Viral Infection

(2014) Brian J. Laidlaw et al.   IMMUNITY

Inchoate CD8+ T Cell Responses in Neonatal Mice Permit Influenza-Induced Persistent Pulmonary Dysfunction

(2014) D. You et al.   JOURNAL OF IMMUNOLOGY

Rapid Proliferation and Differentiation Impairs the Development of Memory CD8+ T Cells in Early Life

(2014) N. L. Smith et al.   JOURNAL OF IMMUNOLOGY

Every Newborn: progress, priorities, and potential beyond survival

(2014) Joy E Lawn et al.   LANCET

Interleukin-8 (CXCL8) production is a signatory T cell effector function of human newborn infants

(2014) Deena Gibbons et al.   NATURE MEDICINE

Updated Guidance for Palivizumab Prophylaxis Among Infants and Young Children at Increased Risk of Hospitalization for Respiratory Syncytial Virus Infection

(2014)   PEDIATRICS

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

(2014) J. M. Schenkel et al.   SCIENCE

Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert

(2014) S. Ariotti et al.   SCIENCE

Quantitative and Qualitative Deficits in Neonatal Lung-Migratory Dendritic Cells Impact the Generation of the CD8+ T Cell Response

(2014) Tracy J. Ruckwardt et al.   PLoS Pathogens

Neonatal Follicular Th Cell Responses Are Impaired and Modulated by IL-4

(2013) I. Debock et al.   JOURNAL OF IMMUNOLOGY

Cytokine-Dependent Induction of CD4+ T cells with Cytotoxic Potential during Influenza Virus Infection

(2013) L. Hua et al.   JOURNAL OF VIROLOGY

Global burden of childhood pneumonia and diarrhoea

(2013) Christa L Fischer Walker et al.   LANCET

Lung niches for the generation and maintenance of tissue-resident memory T cells

(2013) D L Turner et al.   Mucosal Immunology

Immunosuppressive CD71+ erythroid cells compromise neonatal host defence against infection

(2013) Shokrollah Elahi et al.   NATURE

Pediatric sepsis

(2013) Adrienne G Randolph et al.   Virulence

Memory T Cell Subsets, Migration Patterns, and Tissue Residence

(2012) Scott N. Mueller et al.   Annual Review of Immunology

The Molecular Signature of Tissue Resident Memory CD8 T Cells Isolated from the Brain

(2012) L. M. Wakim et al.   JOURNAL OF IMMUNOLOGY

A vaccine strategy that protects against genital herpes by establishing local memory T cells

(2012) Haina Shin et al.   NATURE

Neonatal T-cell maturation and homing receptor responses to Toll-like receptor ligands differ from those of adult naive T cells: relationship to prematurity

(2012) Maricruz Crespo et al.   PEDIATRIC RESEARCH

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Differential Expression of Ly6C and T-bet Distinguish Effector and Memory Th1 CD4+ Cell Properties during Viral Infection

(2011) Heather D. Marshall et al.   IMMUNITY

Retinoic acid induces homing of protective T and B cells to the gut after subcutaneous immunization in mice

(2011) Swantje I. Hammerschmidt et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection

(2011) J. R. Teijaro et al.   JOURNAL OF IMMUNOLOGY

The development of inducible bronchus-associated lymphoid tissue depends on IL-17

(2011) Javier Rangel-Moreno et al.   NATURE IMMUNOLOGY

Respiratory Syncytial Virus-associated Hospitalizations Among Infants and Young Children in the United States, 1997–2006

(2011) Lauren J. Stockman et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Differentiation of Effector CD4 T Cell Populations

(2010) Jinfang Zhu et al.   Annual Review of Immunology

Dynamic T cell migration program provides resident memory within intestinal epithelium

(2010) David Masopust et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Migration of T Cells in Response to Influenza Virus Is Altered in Neonatal Mice

(2010) J. L. Lines et al.   JOURNAL OF IMMUNOLOGY

Fetal and Adult Hematopoietic Stem Cells Give Rise to Distinct T Cell Lineages in Humans

(2010) J. E. Mold et al.   SCIENCE

Neonates harbour highly active γδ T cells with selective impairments in preterm infants

(2009) Deena L. Gibbons et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virus

(2009) Thomas Gebhardt et al.   NATURE IMMUNOLOGY

The Burden of Respiratory Syncytial Virus Infection in Young Children

(2009) Caroline Breese Hall et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phenotypic Changes in Influenza‐Specific CD8+T Cells after Immunization of Children and Adults with Influenza Vaccines

(2008) Xiao‐Song He et al.   JOURNAL OF INFECTIOUS DISEASES

Malnutrition as an enteric infectious disease with long-term effects on child development

(2008) Richard L Guerrant et al.   NUTRITION REVIEWS

Maternal Alloantigens Promote the Development of Tolerogenic Fetal Regulatory T Cells in Utero

(2008) J. E. Mold et al.   SCIENCE