Overcome tumor heterogeneity-imposed therapeutic barriers through convergent genomic biomarker discovery: A braided cancer river model of kidney cancer

Title
Overcome tumor heterogeneity-imposed therapeutic barriers through convergent genomic biomarker discovery: A braided cancer river model of kidney cancer
Authors
Keywords
Intratumor heterogeneity (ITH), Intermetastases heterogeneity (IMH), Branched/divergent evolution, Parallel/convergent gene/pathway/function/phenotype evolution, Braided kidney cancer river model, Targeted therapy, Genomic predictive biomarker, Precision medicine
Journal
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
Volume 64, Issue -, Pages 98-106
Publisher
Elsevier BV
Online
2016-09-13
DOI
10.1016/j.semcdb.2016.09.002

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