Delayed differentiation of potent effector CD8 + T cells reducing viremia and reservoir seeding in acute HIV infection

HIV-specific CD8+ T cells and HIV eradication

(2016) R. Brad Jones et al.   JOURNAL OF CLINICAL INVESTIGATION

Prospective Study of Acute HIV-1 Infection in Adults in East Africa and Thailand

(2016) Merlin L. Robb et al.   NEW ENGLAND JOURNAL OF MEDICINE

Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E

(2016) S. G. Hansen et al.   SCIENCE

Kill

(2016) Lydie Trautmann   Current Opinion in HIV and AIDS

HIV therapeutic vaccines: moving towards a functional cure

(2015) Geetha H Mylvaganam et al.   CURRENT OPINION IN IMMUNOLOGY

Toward a cure for HIV-Seeking effective therapeutic vaccine strategies

(2015) Brigitte Autran   EUROPEAN JOURNAL OF IMMUNOLOGY

Magnitude and Kinetics of CD8 + T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point

(2015) Zaza M. Ndhlovu et al.   IMMUNITY

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

(2015) Kai Deng et al.   NATURE

Cross-Clade Ultrasensitive PCR-Based Assays To Measure HIV Persistence in Large-Cohort Studies

(2014) C. Vandergeeten et al.   JOURNAL OF VIROLOGY

Immune clearance of highly pathogenic SIV infection

(2013) Scott G. Hansen et al.   NATURE

A novel acute HIV infection staging system based on 4th generation immunoassay

(2013) Jintanat Ananworanich et al.   Retrovirology

Cytomegalovirus Vectors Violate CD8+ T Cell Epitope Recognition Paradigms

(2013) S. G. Hansen et al.   SCIENCE

Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies

(2013) Susanne Eriksson et al.   PLoS Pathogens

Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection

(2012) L. Trautmann et al.   BLOOD

Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation

(2012) Liang Shan et al.   IMMUNITY

Initial HIV-1 Antigen-Specific CD8+ T Cells in Acute HIV-1 Infection Inhibit Transmitted/Founder Virus Replication

(2012) S. A. Freel et al.   JOURNAL OF VIROLOGY

Vaccine-induced CD8+ T cells control AIDS virus replication

(2012) Philip A. Mudd et al.   NATURE

Shock and kill

(2012) Steven G. Deeks   NATURE

Impact of Multi-Targeted Antiretroviral Treatment on Gut T Cell Depletion and HIV Reservoir Seeding during Acute HIV Infection

(2012) Jintanat Ananworanich et al.   PLoS One

Massive CD8 T Cell Response to Primary HIV Infection in the Setting of Severe Clinical Presentation

(2011) Gretchen S. Arnoczy et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Timely HAART initiation may pave the way for a better viral control

(2011) Paola Paci et al.   BMC INFECTIOUS DISEASES

Clonotype and Repertoire Changes Drive the Functional Improvement of HIV-Specific CD8 T Cell Populations under Conditions of Limited Antigenic Stimulation

(2011) L. Janbazian et al.   JOURNAL OF IMMUNOLOGY

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

(2011) Scott G. Hansen et al.   NATURE

Early and Prolonged Antiretroviral Therapy Is Associated with an HIV-1-Specific T-Cell Profile Comparable to That of Long-Term Non-Progressors

(2011) Cristina Cellerai et al.   PLoS One

CD8+ Lymphocytes Control Viral Replication in SIVmac239-Infected Rhesus Macaques without Decreasing the Lifespan of Productively Infected Cells

(2010) Nichole R. Klatt et al.   PLoS Pathogens

In Vivo CD8+ T-Cell Suppression of SIV Viremia Is Not Mediated by CTL Clearance of Productively Infected Cells

(2010) Joseph K. Wong et al.   PLoS Pathogens

The Yellow Fever Virus Vaccine Induces a Broad and Polyfunctional Human Memory CD8+ T Cell Response

(2009) R. S. Akondy et al.   JOURNAL OF IMMUNOLOGY

Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

(2009) A. R. Stacey et al.   JOURNAL OF VIROLOGY

Defective Human Immunodeficiency Virus-Specific CD8+ T-Cell Polyfunctionality, Proliferation, and Cytotoxicity Are Not Restored by Antiretroviral Therapy

(2009) S. A. Migueles et al.   JOURNAL OF VIROLOGY

Visualizing Antigen-Specific and Infected Cells in Situ Predicts Outcomes in Early Viral Infection

(2009) Q. Li et al.   SCIENCE

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

(2008) R. Brad Jones et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

(2008) Shawn D Blackburn et al.   NATURE IMMUNOLOGY

CD8+ T cell efficacy in vaccination and disease

(2008) Victor Appay et al.   NATURE MEDICINE

High Throughput Gene Expression Measurement with Real Time PCR in a Microfluidic Dynamic Array

(2008) Sandra L. Spurgeon et al.   PLoS One