Transient CDK4/6 inhibition protects hematopoietic stem cells from chemotherapy-induced exhaustion

Cyclin-Dependent Kinase 4/6 Inhibitors for the Treatment of Breast Cancer: A Review of Preclinical and Clinical Data

(2016) Neelima Vidula et al.   Clinical Breast Cancer

Preclinical Characterization of G1T28: A Novel CDK4/6 Inhibitor for Reduction of Chemotherapy-Induced Myelosuppression

(2016) J. E. Bisi et al.   MOLECULAR CANCER THERAPEUTICS

The history and future of targeting cyclin-dependent kinases in cancer therapy

(2015) Uzma Asghar et al.   NATURE REVIEWS DRUG DISCOVERY

The Role of CDK4/6 Inhibition in Breast Cancer

(2015) C. G. Murphy et al.   ONCOLOGIST

RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer

(2015) Matthew J. Niederst et al.   Nature Communications

Granulocyte colony-stimulating factor exacerbates hematopoietic stem cell injury after irradiation

(2015) Chengcheng Li et al.   Cell and Bioscience

Loss of SPARC protects hematopoietic stem cells from chemotherapy toxicity by accelerating their return to quiescence

(2014) A. Ehninger et al.   BLOOD

G-CSF: From granulopoietic stimulant to bone marrow stem cell mobilizing agent

(2014) Linda J. Bendall et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Comprehensive molecular characterization of urothelial bladder carcinoma

(2014)   NATURE

Proliferation-Dependent Alterations of the DNA Methylation Landscape Underlie Hematopoietic Stem Cell Aging

(2013) Isabel Beerman et al.   Cell Stem Cell

Aging of the hematopoietic system

(2013) Hans-Willem Snoeck   CURRENT OPINION IN HEMATOLOGY

Survival Efficacy of the PEGylated G-CSFs Maxy-G34 and Neulasta in a Mouse Model of Lethal H-ARS, and Residual Bone Marrow Damage in Treated Survivors

(2013) Hui Lin Chua et al.   HEALTH PHYSICS

Multiple Roles of Cyclin-Dependent Kinase 4/6 Inhibitors in Cancer Therapy

(2012) Patrick J. Roberts et al.   JNCI-Journal of the National Cancer Institute

Systematic identification of genomic markers of drug sensitivity in cancer cells

(2012) Mathew J. Garnett et al.   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

The meaning of p16ink4aexpression in tumors

(2011) Agnieszka K. Witkiewicz et al.   CELL CYCLE

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

Stem cells and the aging hematopoietic system

(2010) Isabel Beerman et al.   CURRENT OPINION IN IMMUNOLOGY

Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition

(2010) Søren M. Johnson et al.   JOURNAL OF CLINICAL INVESTIGATION

Acute Myeloid Leukemia or Myelodysplastic Syndrome in Randomized Controlled Clinical Trials of Cancer Chemotherapy With Granulocyte Colony-Stimulating Factor: A Systematic Review

(2010) Gary H. Lyman et al.   JOURNAL OF CLINICAL ONCOLOGY

Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure

(2010) J L Dean et al.   ONCOGENE

Lymphopenia as a Prognostic Factor for Overall Survival in Advanced Carcinomas, Sarcomas, and Lymphomas

(2009) Isabelle Ray-Coquard et al.   CANCER RESEARCH

Mechanisms of hematopoietic stem cell aging

(2009) Aysegul V. Ergen et al.   EXPERIMENTAL GERONTOLOGY

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells

(2008) Adlen Foudi et al.   NATURE BIOTECHNOLOGY

Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

(2008) Keith W. Orford et al.   NATURE REVIEWS GENETICS

A chemical method for fast and sensitive detection of DNA synthesis in vivo

(2008) A. Salic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA