Article
Biochemistry & Molecular Biology
Pai Liu, Sheng Wang, Zhimin Chang, Li Li, Hao Xing, Wen-Fei Dong
Summary: This study investigated the combined exposure of silica nanoparticles (SiNPs) and cadmium on zebrafish embryos, finding that the detrimental effects on heart morphology and vascular endothelial cells were more severe than individual exposures. Gene expression analysis suggested that apoptosis and inflammation may be major pathways underlying the toxicity caused by the combined exposure of SiNPs and CdCl2.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
(2021)
Article
Engineering, Environmental
Miantai Ye, Yunhui Xiang, Jiankang Gong, Xiaoyu Wang, Zhiqiang Mao, Zhihong Liu
Summary: Noninvasively imaging mercury poisoning in living organisms is critical to understanding its toxicity and treatments. Especially, simultaneous fluorescence imaging of Hg2+ and MeHg+ in vivo is helpful to disclose the mysteries of mercury poisoning. A new near-infrared II (NIR II) emissive probe, NIR-Rh-MS, has been designed to visualize mercury toxicity in mice. The probe produces a marked fluorescence signal and displays good sensitivity to Hg2+ and MeHg+. It can penetrate deep into simulated tissues and has successfully monitored the toxicity of Hg2+ in mouse livers and the accumulation of MeHg+ in mouse brains via intravital NIR-II imaging.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Review
Cardiac & Cardiovascular Systems
Lo Lai, Hongyu Qiu
Summary: The use of electronic cigarettes among youth in the USA is a growing public health crisis, with unknown biological impacts on various organ systems, particularly the cardiovascular system. The diverse chemical ingredients in e-cigs, including nicotine and other chemicals, raise concerns about health risks.
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH
(2021)
Article
Engineering, Environmental
Silvia Queipo-Abad, Zoyne Pedrero, Claudia Marchan-Moreno, Khouloud El Hanafi, Sylvain Berail, Warren T. Corns, Yves Cherel, Paco Bustamante, David Amouroux
Summary: The study found that the formation of HgSe nanoparticles did not induce isotopic fractionation, and the presence of MeHg in tissues such as muscle and brain led to variations in Hg isotopic signatures. Screening of Hg biomolecules emphasized the importance of isotopic characterization of these complexes.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Medicine, General & Internal
Yang Bai, Bin Wu, Liangwen Gou, Zhenwei Fang, Ting Xu, Tiejun Zhang, Yuwen Li
Summary: This study investigated the cardiovascular toxicity of febuxostat and allopurinol using the FDA Adverse Event Reporting System (FAERS) database. The results showed that compared to allopurinol, febuxostat may increase the risk of cardiovascular adverse events in patients with gout.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Engineering, Environmental
Haochun Shi, Meng Li, Haoyu Meng, Xuehan Zheng, Kun Zhang, Karl Fent, Jiayin Dai, Yanbin Zhao
Summary: Cardiovascular diseases are a major cause of premature death and a global public health challenge. Using a reduced transcriptome atlas approach, researchers have identified 11 priority compounds with significant effects on the cardiovascular system at the transcriptional level. These compounds, including metals and pesticides/biocides, were experimentally confirmed to dysregulate cardiovascular physiology and lipid profiles in zebrafish.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Environmental Sciences
Haifei Wang, Yajing Zhou, Chao Xu, Yue Cao, Yeyi Xiao, Demin Cai, Yoshinobu Uemoto, Shenglong Wu, Wenbin Bao
Summary: The study characterized the transcriptional profiling of porcine intestinal epithelial cells upon DON exposure, revealing that miR-330 is a key noncoding RNA with significantly increased expression upon DON exposure. High expression of miR-330 inhibits reactive oxygen species production, cell apoptosis, and autophagic flux in cells upon DON exposure.
Article
Environmental Sciences
Guixian Hu, Hao Wang, Jiahong Zhu, Liangliang Zhou, Xue Li, Qiang Wang, Yanhua Wang
Summary: The presence of neonicotinoid pesticide acetamiprid and heavy metal cadmium in water environment has harmful effects on the growth and development of zebrafish. The combined exposure of acetamiprid and cadmium significantly affects the metabolism and gene expression of zebrafish larvae. These findings emphasize the importance of studying the compound toxicity of chemical mixtures on aquatic organisms.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Environmental Sciences
Simone Tosi, Cynthia Sfeir, Edoardo Carnesecchi, Dennis vanEngelsdorp, Marie -Pierre Chauzat
Summary: Multiple stressors, including pesticides, pose threats to bee health. Existing research primarily focuses on lethal effects of pesticides, while sublethal and combined toxicities are less studied. This study provides a comprehensive review and meta-analysis of the lethal, sublethal, and combined toxicity of pesticides on various bee species. It identifies data gaps in sublethal and combined toxicities research and highlights the pesticides and modes of actions that are of greatest concern.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Guiqing Zhou, Jianhui Liu, Xiangyang Li, Yujian Sang, Yue Zhang, Leqiang Gao, Ji Wang, Yang Yu, Wei Ge, Zhiwei Sun, Xianqing Zhou
Summary: The study found that SiNPs can induce reproductive toxicity by inhibiting the expression of miR-450 b-3p, which activates the mitochondrial apoptosis signaling pathways.
ENVIRONMENTAL POLLUTION
(2021)
Article
Biotechnology & Applied Microbiology
Soonkyu Hwang, Namil Lee, Donghui Choe, Yongjae Lee, Woori Kim, Ji Hun Kim, Gahyeon Kim, Hyeseong Kim, Neung-Ho Ahn, Byoung-Hee Lee, Bernhard O. Palsson, Byung-Kwan Cho
Summary: In this study, the regulatory elements of transcription and translation in Streptomyces griseus were analyzed using multiple "omics" datasets. Several important regulators and elements were identified, providing a foundation for genetic engineering to improve secondary metabolite production in Streptomyces.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Engineering, Multidisciplinary
Ahmed El-Attar
Summary: The research aims at understanding the load distribution mechanism of high rise buildings constructed on the combined piled raft system (CPRS) under earthquake conditions. Further insights into the interaction between piles, soil, and raft are needed through parametric studies. The interaction mechanisms are mainly based on inertia and kinematic interaction under seismic and vertical loads.
AIN SHAMS ENGINEERING JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
YanFeng Wang, Chanjuan Cui, Xiayang Ren, Xinran Dong, Wei Cui
Summary: This study investigated the cardiovascular toxicities associated with angiogenesis inhibitors, specifically monoclonal antibodies (mAbs) and tyrosine kinase inhibitors (TKIs), targeting vascular endothelial growth factor (VEGF). The analysis revealed differences in the frequency, spectrum, timing, and outcomes of cardiovascular adverse events between mAbs and TKIs.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Oncology
A. Palazzo, C. Ciccarese, R. Iacovelli, M. C. Cannizzaro, A. Stefani, L. Salvatore, E. Bria, G. Tortora
Summary: The use of PARP inhibitors in cancer treatment is associated with an increased risk of cardiovascular events, hypertension, and thromboembolic events. However, routine cardiovascular monitoring may not be necessary in asymptomatic patients due to the low incidence of high-grade adverse events.
Article
Environmental Sciences
Xin Wang, Fan Chen, Jian Lu, Mengqi Wu, Jiagao Cheng, Wenping Xu, Zhong Li, Yang Zhang
Summary: This study evaluated the toxicity of the pesticide acetochlor (ACT) and its chiral isomers in a zebrafish model. The results showed that ACT and its chiral isomers disrupt zebrafish embryo development, induce oxidative stress, abnormal lipid metabolism, and apoptosis. Additionally, they also cause cardiovascular damage, including reduced heart rate, decreased red blood cell flow rate, and vascular damage. Furthermore, the study found that (+)-S-ACT has a significant impact on genes involved in cardiac and vascular development. These findings raise concerns about the potential risks and impact on human health posed by chiral isomeric pesticides.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Cell Biology
Ji Wang, Yang Li, Junchao Duan, Man Yang, Yang Yu, Lin Feng, Xiaozhe Yang, Xianqing Zhou, Zhendong Zhao, Zhiwei Sun
Article
Environmental Sciences
Yannan Zhang, Yanbo Li, Zhixiong Shi, Jing Wu, Xiaozhe Yang, Lin Feng, Lihua Ren, Junchao Duan, Zhiwei Sun
Article
Environmental Sciences
Xiaozhe Yang, Lin Feng, Yannan Zhang, Hejing Hu, Yanfeng Shi, Shuang Liang, Tong Zhao, Yang Fu, Junchao Duan, Zhiwei Sun
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2018)
Review
Environmental Sciences
Baiyang Sun, Yanfeng Shi, Xiaozhe Yang, Tong Zhao, Junchao Duan, Zhiwei Sun
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2018)
Article
Environmental Sciences
Xiaozhe Yang, Lin Feng, Yannan Zhang, Hejing Hu, Yanfeng Shi, Shuang Liang, Tong Zhao, Lige Cao, Junchao Duan, Zhiwei Sun
SCIENCE OF THE TOTAL ENVIRONMENT
(2018)
Article
Environmental Sciences
Xiaozhe Yang, Lin Feng, Yannan Zhang, Yanfeng Shi, Shuang Liang, Tong Zhao, Baiyang Sun, Junchao Duan, Zhiwei Sun
Article
Nanoscience & Nanotechnology
Lin Feng, Xiaozhe Yang, Yanfeng Shi, Shuang Liang, Tong Zhao, Junchao Duan, Zhiwei Sun
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2018)
Article
Environmental Sciences
Yanfeng Shi, Tong Zhao, Xiaozhe Yang, Baiyang Sun, Yang Li, Junchao Duan, Zhiwei Sun
SCIENCE OF THE TOTAL ENVIRONMENT
(2019)
Article
Toxicology
Lin Feng, Xiaozhe Yang, Shuang Liang, Qing Xu, Mark R. Miller, Junchao Duan, Zhiwei Sun
PARTICLE AND FIBRE TOXICOLOGY
(2019)
Article
Environmental Sciences
Xiaozhe Yang, Tong Zhao, Lin Feng, Yanfeng Shi, Jinjin Jiang, Shuang Liang, Baiyang Sun, Qing Xu, Junchao Duan, Zhiwei Sun
ENVIRONMENT INTERNATIONAL
(2019)
Article
Environmental Sciences
Jiangyan Liu, Shuang Liang, Zhou Du, Jingyi Zhang, Baiyang Sun, Tong Zhao, Xiaozhe Yang, Yanfeng Shi, Junchao Duan, Zhiwei Sun
ENVIRONMENTAL POLLUTION
(2019)
Article
Otorhinolaryngology
Yuzhoujia Deng, Chengshuo Wang, Shen Shen, Xiaozhe Yang, Hongfei Lou, Luo Zhang
Summary: The study found that acute alcohol consumption may impair nasal patency, regardless of the amount consumed. Individuals with allergic rhinitis may be more susceptible to nasal obstruction after alcohol intake compared to those without allergic rhinitis.
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY
(2022)
Article
Medicine, Research & Experimental
Xiaozhe Yang, Shen Shen, Yuzhoujia Deng, Chengshuo Wang, Luo Zhang
Summary: The study revealed that air pollution exacerbates the severity of CRSwNP, with PM2.5 potentially being a risk factor for the endotype of ECRSwNP.
Article
Toxicology
Jing Wu, Jie Zhang, Jihua Nie, Junchao Duan, Yanfeng Shi, Lin Feng, Xiaozhe Yang, Yan An, Zhiwei Sun
TOXICOLOGY RESEARCH
(2019)
Article
Environmental Sciences
Hejing Hu, Collins Otieno Asweto, Jing Wu, Yanfeng Shi, Lin Feng, Xiaozhe Yang, Shuang Liang, Lige Cao, Junchao Duan, Zhiwei Sun
Article
Environmental Sciences
Toshimi Nakajima, Mao Kuragano, Makoto Yamada, Ryo Sugimoto
Summary: This study compared the contribution of submarine groundwater discharge (SGD) to river nutrient budgets at nearshore and embayment scales, and found that SGD-derived nutrients become more important at larger spatial scales.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Fan Liu, Lei Zhang, Chongyang Zhang, Ziguang Chen, Jingguang Li
Summary: NO2 emissions from wall-mounted gas stoves used for household heating have become a significant source of indoor pollution in Chinese urban areas. The high indoor concentration of NO2 poses potential health risks to residents. It is urgently necessary to establish relevant regulations and implement emission reduction technologies to reduce NO2 emissions from wall-mounted gas stoves.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Letter
Environmental Sciences
Hans Peter H. Arp, Raoul Wolf, Sarah E. Hale, Sivani Baskaran, Juliane Gluege, Martin Scheringer, Xenia Trier, Ian T. Cousins, Harrie Timmer, Roberta Hofman-Caris, Anna Lennquist, Andre D. Bannink, Gerard J. Stroomberg, Rosa M. A. Sjerps, Rosa Montes, Rosario Rodil, Jose Benito Quintana, Daniel Zahn, Herve Gallard, Tobias Mohr, Ivo Schliebner, Michael Neumann
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Philomina Onyedikachi Peter, Binessi Edouard Ifon, Francois Nkinahamira, Kayode Hassan Lasisi, Jiangwei Li, Anyi Hu, Chang-Ping Yu
Summary: This study investigates the relationship between dissolved organic matter (DOM) and Rare Earth Elements (REEs) in sediments from Yundang Lagoon, China. The results show four distinct fluorescent components, with protein-like substances being the most prevalent. Additionally, the total fluorescence intensity and LREE concentrations exhibit a synchronized increase from Outer to Inner to Songbai Lake core sediments. The findings demonstrate a strong correlation between DOM content and pollution levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Surya Gupta, Pasquale Borrelli, Panos Panagos, Christine Alewell
Summary: The objective of this study is to incorporate soil hydraulic properties into the erodibility factor (K) of USLE-type models. By modifying and improving the existing equations for soil texture and permeability, the study successfully included information on saturated hydraulic conductivity (Ksat) into the calculation of K factor. Using the Random Forest machine learning algorithm, two independent K factor maps with different spatial resolutions were generated. The results show that the decrease in K factor values has a positive impact on the modeling of soil erosion rates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jesmin Akter, Wendy J. M. Smith, Yawen Liu, Ilho Kim, Stuart L. Simpson, Phong Thai, Asja Korajkic, Warish Ahmed
Summary: The choice of workflow in wastewater surveillance has a significant impact on SARS-CoV-2 concentrations, while having minimal effects on HF183 and no effect on HAdV 40/41 concentrations. Certain components in the workflow can be interchangeable, but factors such as buffer type, chloroform, and homogenization speed can affect the recovery of viruses and bacteria.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yu Luo, Xueting Yang, Diwei Wang, Hongmei Xu, Hongai Zhang, Shasha Huang, Qiyuan Wang, Ningning Zhang, Junji Cao, Zhenxing Shen
Summary: Atmospheric PM2.5, which can generate reactive oxygen species (ROS), is associated with cardiorespiratory morbidity and mortality. The study found that both the mass concentration of PM2.5 and the DTT activity were higher during the heating season than during the nonheating season. Combustion sources were the primary contributors to DTT activity during the heating season, while secondary formation dominated during the nonheating season. The study also revealed that biomass burning had the highest inherent oxidation potential among all sources investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Erin L. Murphy, Leah R. Gerber, Chelsea M. Rochman, Beth Polidoro
Summary: Plastic pollution has devastating consequences for marine organisms. This study uses a trait-based framework to develop a vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i. The index ranks 63 study species based on their vulnerability to macroplastic pollution, providing valuable information for species monitoring and management priorities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Kenji Maurice, Amelia Bourceret, Sami Youssef, Stephane Boivin, Liam Laurent-Webb, Coraline Damasio, Hassan Boukcim, Marc-Andre Selosse, Marc Ducousso
Summary: Growing pressure from climate change and agricultural land use is destabilizing soil microbial community interactions. Little is known about microbial community resistance and adaptation to disturbances, hindering our understanding of recovery latency and implications for ecosystem functioning. This study found that anthropic disturbance and natural disturbance have different effects on the topology and stability of soil microbial networks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yunhao Li, Yali Feng, Haoran Li, Yisong Yao, Chenglong Xu, Jinrong Ju, Ruiyu Ma, Haoyu Wang, Shiwei Jiang
Summary: Deep-sea mining poses a serious threat to marine ecosystems and human health by disturbing sediment and transmitting metal ions through the food chain. This study developed a new regenerative adsorption material, OMN@SA, which effectively removes metal ions. The adsorption mechanism and performance of the material for metal ion fixation were investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Antonio Medici, Margherita Lavorgna, Marina Isidori, Chiara Russo, Elena Orlo, Giovanni Luongo, Giovanni Di Fabio, Armando Zarrelli
Summary: Valsartan, a widely used antihypertensive drug, has been detected in high concentrations in surface waters due to its unchanged excretion and incomplete degradation in wastewater treatment plants. This study investigated the degradation of valsartan and identified 14 degradation byproducts. The acute and chronic toxicity of these byproducts were evaluated in key organisms in the freshwater trophic chain.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jiang Lin, Lianbao Chi, Qing Yuan, Busu Li, Mingbao Feng
Summary: This study investigated the photodegradation behavior and product formation of two representative pharmaceuticals in simulated estuary water. The study found that the formed transformation products of these pharmaceuticals have potential toxicity on marine organisms, including oxidative stress and damage to cellular components.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Hua Fang, Dongdong Jiang, Ye He, Siyi Wu, Yuehong Li, Ziqi Zhang, Haoting Chen, Zixin Zheng, Yan Sun, Wenxiang Wang
Summary: This study revealed that exposure to lower levels of air pollutants led to decreased pregnancy rates, with PM10, NO2, SO2, and CO emerging as the four most prominent pollutants. Individuals aged 35 and above exhibited heightened susceptibility to pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Ali Shaan Manzoor Ghumman, Rashid Shamsuddin, Amin Abbasi, Mohaira Ahmad, Yoshiaki Yoshida, Abdul Sami, Hamad Almohamadi
Summary: In this study, inverse vulcanized polysulfides (IVP) were synthesized by reacting molten sulfur with 4-vinyl benzyl chloride, and then functionalized using N-methyl D-glucamine (NMDG). The functionalized IVP showed a high mercury adsorption capacity and a machine learning model was developed to predict the amount of mercury removed. Furthermore, the functionalized IVP can be regenerated and reused, providing a sustainable and cost-effective adsorbent.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Valeria Palumbo, Maria Paola Scioli, Erica Giacobbi, Francesca Servadei, Gerry Melino, Alessandro Mauriello, Manuel Scimeca
Summary: This study investigated the presence of aluminum in human colon cancer samples and its potential association with biological processes involved in cancer progression. Aluminum was found in tumor areas of 24% of patients and was associated with epithelial to mesenchymal transition (EMT) and cell death. Additional analyses revealed higher tumor mutational burden and mutations in genes related to EMT and apoptosis in aluminum-positive colon cancers. Understanding the molecular mechanisms of aluminum toxicity may improve strategies for the management of colon cancer patients.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)