Recent advances in DNAzyme-based gene silencing

A Silver DNAzyme

(2016) Runjhun Saran et al.   ANALYTICAL CHEMISTRY

Knockdown of TNF-α by DNAzyme gold nanoparticles as an anti-inflammatory therapy for myocardial infarction

(2016) Inthirai Somasuntharam et al.   BIOMATERIALS

Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy

(2016) Hong-Min Meng et al.   CHEMICAL SOCIETY REVIEWS

A Targeted DNAzyme-Nanocomposite Probe Equipped with Built-in Zn2+ Arsenal for Combined Treatment of Gene Regulation and Drug Delivery

(2016) Zhi-Mei He et al.   Scientific Reports

Tandem DNAzymes for mRNA cleavage: Choice of enzyme, metal ions and the antisense effect

(2015) Feng Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A New Na+-Dependent RNA-Cleaving DNAzyme with over 1000-fold Rate Acceleration by Ethanol

(2015) Wenhu Zhou et al.   CHEMBIOCHEM

A review: microRNA detection methods

(2015) Tian Tian et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

In vitro selection of a sodium-specific DNAzyme and its application in intracellular sensing

(2015) Seyed-Fakhreddin Torabi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional DNA-Containing Nanomaterials: Cellular Applications in Biosensing, Imaging, and Targeted Therapy

(2014) Hao Liang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Design and Biosensing of Mg2+-Dependent DNAzyme-Triggered Ratiometric Electrochemiluminescence

(2014) Yan Cheng et al.   ANALYTICAL CHEMISTRY

Turn-On Fluorescence Sensor for Intracellular Imaging of Glutathione Using g-C3N4 Nanosheet–MnO2 Sandwich Nanocomposite

(2014) Xiao-Long Zhang et al.   ANALYTICAL CHEMISTRY

In Vitro Selection of a New Lanthanide-Dependent DNAzyme for Ratiometric Sensing Lanthanides

(2014) Po-Jung Jimmy Huang et al.   ANALYTICAL CHEMISTRY

Photocaged DNAzymes as a General Method for Sensing Metal Ions in Living Cells

(2014) Kevin Hwang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Activatable Fluorescence/MRI Bimodal Platform for Tumor Cell Imaging via MnO2 Nanosheet–Aptamer Nanoprobe

(2014) Zilong Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A new colorimetric strategy for monitoring caspase 3 activity by HRP-mimicking DNAzyme–peptide conjugates

(2013) Zhaojuan Zhou et al.   ANALYST

A highly sensitive and selective homogenous assay for profiling microRNA expression

(2013) Huimin Deng et al.   BIOSENSORS & BIOELECTRONICS

DNAzyme Delivery Approaches in Biological Settings

(2013) Cecilia Chan et al.   CURRENT MEDICINAL CHEMISTRY

Inhibition of vein graft stenosis with a c-jun targeting DNAzyme in a cationic liposomal formulation containing 1,2-dioleoyl-3-trimethylammonium propane (DOTAP)/1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE)

(2013) Yue Li et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

A DNAzyme-Gold Nanoparticle Probe for Uranyl Ion in Living Cells

(2013) Peiwen Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Deoxyribozyme-Modified Nanoparticles for RNAi-Independent Gene Regulation

(2012) Kevin Yehl et al.   ACS Nano

Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC)

(2012) J. Siepmann et al.   ADVANCED DRUG DELIVERY REVIEWS

Antagonism of microRNA Function in Zebrafish Embryos by Using Locked Nucleic Acid Enzymes (LNAzymes)

(2012) Hemant Suryawanshi et al.   CHEMBIOCHEM

Use of DNAzymes for cancer research and therapy

(2012) ZhiJie Xu et al.   CHINESE SCIENCE BULLETIN

Development of drug delivery systems for the dermal application of therapeutic DNAzymes

(2012) Thomas Schmidts et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Functional delivery of DNAzyme with iron oxide nanoparticles for hepatitis C virus gene knockdown

(2011) Soo-Ryoon Ryoo et al.   BIOMATERIALS

Aptamer-DNAzyme hairpins for biosensing of Ochratoxin A

(2011) Cheng Yang et al.   BIOSENSORS & BIOELECTRONICS

Discovery of Cationic Polymers for Non-Viral Gene Delivery Using Combinatorial Approaches

(2011) Sutapa Barua et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Mismatch discrimination and efficient photomodulation with split 10–23 DNAzymes

(2011) Brittani K. Ruble et al.   INORGANICA CHIMICA ACTA

A Ligation-Triggered DNAzyme Cascade for Amplified Fluorescence Detection of Biological Small Molecules with Zero-Background Signal

(2011) Li-Min Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intracellular Glutathione Detection Using MnO2-Nanosheet-Modified Upconversion Nanoparticles

(2011) Renren Deng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

pH-Triggered Controlled Drug Release from Mesoporous Silica Nanoparticles via Intracelluar Dissolution of ZnO Nanolids

(2011) Faheem Muhammad et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Locked and Unlocked Nucleosides in Functional Nucleic Acids

(2011) Holger Doessing et al.   MOLECULES

Catalytic and Molecular Beacons for Amplified Detection of Metal Ions and Organic Molecules with High Sensitivity

(2010) Xiao-Bing Zhang et al.   ANALYTICAL CHEMISTRY

“Locked onto the Target”: Increasing the Efficiency of Antagomirzymes Using Locked Nucleic Acid Modifications

(2010) Harleen Kaur et al.   BIOCHEMISTRY

10-23 DNAzyme modified with (2′R)- and (2′S)-2′-deoxy-2′-C-methyluridine in the catalytic core

(2010) Laura Robaldo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Easy-to-use dipstick tests for detection of lead in paints using non-cross-linked gold nanoparticle–DNAzyme conjugates

(2010) Debapriya Mazumdar et al.   CHEMICAL COMMUNICATIONS

A highly selective lead sensor based on a classic lead DNAzyme

(2010) Tian Lan et al.   CHEMICAL COMMUNICATIONS

Locked Nucleic Acids: Promising Nucleic Acid Analogs for Therapeutic Applications

(2010) Rakesh N. Veedu et al.   CHEMISTRY & BIODIVERSITY

Endosomal escape pathways for delivery of biologicals

(2010) Amir K. Varkouhi et al.   JOURNAL OF CONTROLLED RELEASE

Activation and Deactivation of DNAzyme and Antisense Function with Light for the Photochemical Regulation of Gene Expression in Mammalian Cells

(2010) Douglas D. Young et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

EBV-LMP1-targeted DNAzyme restrains nasopharyngeal carcinoma growth in a mouse C666-1 xenograft model

(2010) Xia Ke et al.   MEDICAL ONCOLOGY

The 10–23 DNA Enzyme Generated by a Novel Expression Vector Mediate Inhibition of Taco Expression in Macrophage

(2010) Junming Li et al.   OLIGONUCLEOTIDES

Sequence-Related Off-Target Effect of Dz13 Against Human Tumor Cells and Safety in Adult and Fetal Mice Following Systemic Administration

(2010) Crispin R. Dass et al.   OLIGONUCLEOTIDES

Deoxyribozymes: Selection Design and Serendipity in the Development of DNA Catalysts†

(2009) Scott K. Silverman   ACCOUNTS OF CHEMICAL RESEARCH

Antagomirzymes: Oligonucleotide Enzymes That Specifically Silence MicroRNA Function

(2009) Vaibhav M. Jadhav et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Functional Nucleic Acid Sensors

(2009) Juewen Liu et al.   CHEMICAL REVIEWS

DNAzyme Delivery Systems: Getting Past First Base

(2009) Mei Lin Tan et al.   Expert Opinion on Drug Delivery

DNAzymes and their therapeutic possibilities

(2009) C. W. S. Chan et al.   INTERNAL MEDICINE JOURNAL

An Allosteric Dual-DNAzyme Unimolecular Probe for Colorimetric Detection of Copper(II)

(2009) Bin-Cheng Yin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy

(2009) N. Cartier et al.   SCIENCE

Highly Sensitive and Selective Colorimetric Sensors for Uranyl (UO22+): Development and Comparison of Labeled and Label-Free DNAzyme-Gold Nanoparticle Systems

(2008) Jung Heon Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNAzyme technology and cancer therapy: cleave and let die

(2008) C. R. Dass et al.   MOLECULAR CANCER THERAPEUTICS